DoW Reconstructive Transplant, Investigator-Initiated Research Award
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The fiscal year 2026 Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award, administered by the Defense Health Agency, supports studies aimed at advancing the science and clinical practice of vascularized composite allotransplantation (VCA). The program targets improvements in access, safety, and quality of life for catastrophically injured Service Members, Veterans, and the general public. Eligible research spans from basic and translational phases to preclinical animal models and clinical research in human subjects, though clinical trials are explicitly excluded. Awards are capped at 1.0 million dollars with a maximum period of performance of three years. Applicants must demonstrate military relevance and align their projects with at least one FY26 RTRP Focus Area. Proposals require a rigorous study design, a strong statistical plan, and the inclusion of relevant preliminary or published data. The selection process involves a two-tier review consisting of a technical peer review and a programmatic review. Key submission requirements include active registration in SAM.gov, eBRAP, and Grants.gov, with a pre-application deadline of October 21, 2026, and a full application deadline of November 4, 2026. Required documentation includes a Statement of Work, Impact Statement, Military Relevance document, and disclosure of foreign affiliations for all key personnel.
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Full Description
Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award supports studies that have the potential to make an important contribution to reconstructive transplant research, patient care, and/or quality of life. All projects must demonstrate solid scientific rationale with military-relevant utility. The Investigator-Initiated Research Award does not support clinical trials.
Distinctive Features:
· Scope: Applications may focus on any phase of research from basic through translational, including preclinical studies in animal models, and clinical research in human subjects or human anatomical substances.
· Study Design and Feasibility: The study design should be rigorous and support maximal reproducibility and translational feasibility. A strong statistical plan with appropriate power analysis is important.
· Impact: Project results should have the potential for long- and short-term impact on the reconstructive transplant research field and/or patient community. Projects should address at least one of the FY26 RTRP Focus Areas.
· Preliminary Data: Preliminary and/or published data that are relevant to reconstructive transplantation and support the rationale for the proposed research must be included.
· Military Relevance: All projects must be responsive to the health care needs of military Service Members and/or Veterans recovering from traumatic injury, and/or their Family members, caregivers, or clinicians, as well as the general public. Collaboration with military researchers and clinicians is encouraged but not required.
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