DoW Breast Cancer, Breakthrough Award Levels 1 and 2
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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The Department of Defense, through the Defense Health Agency Contracting Activity, is soliciting applications for the Fiscal Year 2026 Breast Cancer Research Program Breakthrough Award Levels 1 and 2. This initiative supports high-impact research aimed at achieving breakthroughs in breast cancer, requiring all applications to address specific overarching challenges or provide a strong justification for an exception. The program offers two funding levels, with Level 2 including a Population Science Studies option that may qualify for increased funding and an extended performance period. Eligible applicants may apply as a single Principal Investigator or as a partnership between an Initiating PI and a Partnering PI. For those utilizing the partnering option, the Initiating PI must submit the pre-application, while both must submit full applications to avoid administrative withdrawal. The response deadline for this solicitation is November 18, 2026.
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Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Breakthrough Award mechanism supports promising research with high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the FY26 BCRP overarching challenges or provide adequate justification for exception. Applications must address the challenge in a way that can lead to a breakthrough and have major impact. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support major (but not all) stages of research that will lead to clinical application. Each level specifies a distinct research scope. This program announcement discusses the Breakthrough Award Levels 1 and 2.
Distinctive Features:
* This funding mechanism allows for applications submitted under Funding Level 1 or Funding Level 2. Funding Level 2 also includes a Population Science Studies option. With compelling justification, population science studies may request higher levels of funding and an additional year in the period of performance.
* This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. For the Partnering PI Option (PPIO), only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. Be advised, failure to submit all associated (Initiating and Partnering PI) applications by the deadline may result in administrative withdrawal.
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