This Government Contract opportunity from Department Of Health And Human Services was posted on July 6, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Advanced Fluorescence Labeling R&D

Closed

Federal

Submission Closed07/11/2026, 03:00:00 AM UTC

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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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Technical Research Subcontractor / ConsultantThis subcontract opportunity, issued by the U.S. Air Force under the Department of Defense, seeks a Technical Research Subcontractor or Consultant to support prime contractors on Department of War SBIR projects. The selected entity will be responsible for conducting specialized research and technical analysis to determine feasibility, developing methods to meet technical objectives, and delivering comprehensive data and research findings for final reports. The contract is a total small business set-aside under NAICS code 541715, requiring the subcontractor to have fewer than 500 employees. Key compliance requirements include adherence to CMMC standards for handling Controlled Unclassified Information and Federal Contract Information, the implementation of OCI mitigation plans, and strict following of protocols regarding Recombinant DNA or Human and Animal Subjects. Responses are due by November 25, 2026.

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Research Institution Collaborative PartnerThe Research Institution Collaborative Partner subcontract, issued by the U.S. Air Force under the Department of Defense, focuses on primary research and development for STTR projects. The selected partner will be responsible for conducting laboratory research, theoretical modeling, data analysis, and technical validation to assess the feasibility of proposed concepts. Key deliverables include technical reports, research findings, and comprehensive feasibility data. This opportunity is specifically set aside for small businesses under the SBIR/STTR mandate with fewer than 500 employees, and it requires the partner to be a non-profit research institution, such as a university or a Federally Funded Research and Development Center. Interested parties must submit their responses by November 25, 2026.

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RF and Signal Processing Engineering ServicesThis subcontract for RF and Signal Processing Engineering Services supports U.S. Air Force telemetry projects by providing research and design for signal synchronization architectures. The scope of work includes developing synchronization algorithms, analyzing signal drift, and designing clock distribution networks utilizing tools such as MATLAB/Simulink or ADS. The primary deliverables consist of synchronization architecture designs and technical feasibility reports. This opportunity is a total small business set-aside under NAICS code 541715. Due to the nature of the work, contractors must be U.S. citizens to comply with ITAR/EAR export controls and must maintain CMMC compliance for handling Controlled Unclassified Information. Responses are due by November 25, 2026.

U.S. Air Force

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about 4 hours ago

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in 28 days

AI Contract Overview

The contract titled Advanced Fluorescence Labeling R&D is a small business set-aside subcontract issued by the National Institutes of Health under the Department of Health and Human Services, aimed at advancing fluorescence labeling techniques specifically optimized for use with AIM microscopes at the NIH facility in Bethesda, Maryland. The work requires independent research and development to enhance the precision, brightness, and stability of fluorescent labels for improved imaging performance on these specialized microscopes, with the goal of enabling higher-resolution biological imaging for scientific applications critical to public health research. This opportunity is open exclusively to small businesses as defined by the SBA and is classified under NAICS code 541715 for research and development in the physical, engineering, and life sciences. The solicitation was posted on July 6, 2026, with a strict response deadline of July 11, 2026, at 3:00 AM Eastern Time. All performance must be conducted at the Bethesda location, and the contractor is expected to deliver innovative solutions that directly support the NIH’s mission in advancing biomedical imaging capabilities without reliance on existing proprietary methods already in widespread use.

General Info

Small business R&D contract to enhance fluorescence labeling for AIM microscopes at NIH Bethesda, Maryland.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

SBA

Documents

This scope was carved out of 75N98026Q00739.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Specialized on-site fluorescent microscopy services

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Timeline

PhaseClosed

PostedJul 6

subcontract

Response DeadlineJul 11

Deadline has passed

Submission Closed

07/11/2026, 03:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Office AddressN/A

ContactsNo contact information available

Full Description

Conduct independent research and development to improve fluorescence labeling techniques specifically for use with AIM microscopes at the NIH facility.

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Advanced Fluorescence Labeling R&D

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