Advanced Multichannel Multispectral Photodetection System

The National Institute of Standards and Technology (NIST), through its Biophysical and Biomedical Measurement Group within the Physical Measurement Laboratory, is seeking market input for an advanced multichannel multispectral photodetection system to integrate into its unique Serial Flow Cytometer. This system is critical for enabling high-temporal and high-spectral resolution optical measurements of biological micro and nanoparticles, including cells, gene therapy nanoparticles, and calibration particles, to support the development of microscale measurement science and advance Critical and Emerging Technologies in biotechnology. The photodetector must perform hyperspectral fluorescence detection with at least 16 non-overlapping spectral channels, each with a width of 20 nm or less, covering a spectral range from no higher than 450 nm to at least 750 nm, and must be capable of detecting light from four or more laser sources either through multiplexed or separated detection paths. The system must accept fiber optic inputs via SMA905 connectors with a minimum numerical aperture of 0.1 and core diameter of 105 micrometers, and employ a detector technology such as photomultiplier tube, avalanche photodiode, silicon photomultiplier, or hybrid design. Integration requires seamless connection to NIST’s optical routing and voltage signal recording systems. All responses must be submitted by email no later than June 12, 2026, and are limited to four pages, including attachments, in Word 365, Excel 365, or PDF format. Respondents are required to provide their company name, address, point of contact, Unique Entity ID if registered in SAM.gov, and business size classification under NAICS code 334516. They must specify the manufacturer and model of their proposed equipment, its country of origin, and whether it is U.S. manufactured, along with technical specifications meeting or exceeding NIST’s draft requirements. Additional details must include standard commercial terms such as delivery timelines after order acceptance, FOB shipping terms, warranty coverage, setup and test procedures, and cleanup protocols. Respondents are also requested to outline available installation, training, and maintenance services, and to identify any aspects of the minimum specifications they cannot meet, along with suggestions for improvement. Proprietary information should not be included. This notice serves solely as market research and is not a solicitation or commitment to award a contract.