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This Solicitation opportunity from Department Of Defense was posted on December 21, 2023. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

AIM G-NOMES

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714
New
Grant
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-012
The National Institute of Allergy and Infectious Diseases (NIAID) has issued solicitation RFA-AI-28-012 to establish a consortium of Translational Centers Using Microphysiological Systems for Infectious Diseases (TCMID). The primary objective is to refine and validate human tissue models using Microphysiological Systems (MPS) to a level consistent with regulatory qualifications, thereby promoting their adoption by product developers and reducing reliance on laboratory animals. This initiative aligns with NIH and FDA guidance on New Approach Methodologies (NAMs) to accelerate the development of safer medical interventions by capturing human variability and patient-specific characteristics. The program is structured around an Administrative Core, a Qualification Core, and Scientific Cores, with a heavy emphasis on technical readiness, reproducibility, and regulatory acceptance. Key deliverables include the validation of assays for specific endpoints and the submission of regulatory packages. Applicants must be domestic entities, as foreign organizations and foreign subawards are strictly prohibited. Required personnel must possess deep expertise in infectious diseases, MPS platforms, bioinformatics, and FDA submission processes. Applications are due by January 29, 2027, and must be submitted via the NIH ASSIST system or approved institutional system-to-system solutions. Evaluation is based on an overall impact score considering the project's significance, the suitability of the investigators, and the quality of the institutional environment. Mandatory application components include a Data Management and Sharing Plan and a Benchmarks and Timeline PDF not exceeding six pages. Awardees must also adhere to strict cybersecurity incident reporting guidelines, notifying HHS within 48 hours of any discovery.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 3 months
NAICS: 541714
New
Grant
Immune Tolerance Network (UM1 Clinical Trial Required)
Solicitation # RFA-AI-28-005
The National Institutes of Health, under the Department of Health and Human Services, is seeking applications through solicitation RFA-AI-28-005 to continue the Immune Tolerance Network (ITN). This cooperative agreement aims to develop tolerogenic therapies for immune-mediated disorders, specifically focusing on autoimmune diseases, allergic diseases and asthma, and the immune-mediated consequences of transplantation. The network operates through four integrated functional areas: Leadership, Clinical Operations, Core Laboratory, and Bioinformatics. Its primary objectives include designing and conducting clinical trials, performing integrated mechanistic studies, and sharing research results. Eligible applicants include small businesses and other for-profit organizations, though non-domestic entities are ineligible. Applications are evaluated based on scientific and technical merit, with a primary focus on significance and the likelihood of exerting a sustained influence on the research field. Key requirements include maintaining active registrations in SAM.gov, eRA Commons, and Grants.gov, as well as adhering to strict cybersecurity incident reporting and human subject protection protocols. The project requires a minimum effort of 3.6 person months per year for the PD/PI and mandates participation in a kick-off meeting in Bethesda, Maryland, and bi-annual steering meetings. Applications must follow specific page limits for the research strategy subsections and include detailed plans for clinical trial implementation, data management, and biorepository services.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 3 months
NAICS: 541714
New
Federal
Pre-Award Synopsis Texas Shield
Solicitation # DARPA-SN-27-07
The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), intends to enter into an agreement with The University of Texas System consortium of universities for the Texas Shield Program. This integrated research initiative, identified by solicitation number DARPA-SN-27-07 and NAICS code 541714, focuses on developing autonomous and semi-autonomous medical technologies and scalable solutions for critical medical consumables. The primary goal is to support lifesaving medical care in contested, austere, and resource-limited environments. Key technical areas of focus include autonomous medical and robotic surgical systems, casualty evacuation, artificial-blood and supply innovation, AI-enabled clinical decision support, and mass-casualty science and simulation. This notice is a pre-award synopsis and is not a request for proposals or a competitive solicitation. Interested entities are invited to submit information by November 15, 2026, to TexasShieldxBTO@darpa.mil detailing their technical expertise, integrated research infrastructure, clinical-validation capabilities, and multi-institutional coordination capacity. Additionally, respondents must describe their consortium organizational structure, commercialization capabilities, facility clearance levels, and their ability to handle Controlled Unclassified Information. The government will not reimburse any costs associated with the preparation or submission of information in response to this notice.
Defense Advanced Research Projects Agcy

POSTED

5 days ago

DEADLINE

in 25 days
NAICS: 541714
New
Federal
Q--AMPLICON SEQUENCING SERVICES
Solicitation # 140G0226Q0047
Solicitation 140G0226Q0047 is a firm-fixed-price request for a Blanket Purchase Agreement (BPA) to provide next generation amplicon sequencing services for the USGS Upper Midwest Water Science Center’s Michigan Bacteriological Research Laboratory. The scope of work includes providing all equipment, labor, travel, and materials necessary to support research on bacterial pathogens, harmful algal blooms, microbial ecology, antibiotic resistance, and microbial source tracking. Key technical requirements include the use of Illumina MiSeq or AVITI sequencing technologies and the potential for library preparation for 16S V4 amplicon sequencing. The BPA has a total not-to-exceed value of 250,000 dollars with an estimated period of performance from September 17, 2026, to September 16, 2031. The award process prioritizes non-priced factors significantly over cost, focusing on the offeror's qualifications and technical performance. Evaluation criteria include a detailed listing of on-site equipment and calibration dates, personnel experience, internal quality assurance procedures, and a technical narrative not exceeding two pages. Performance will be executed in Lansing, Michigan, with delivery terms set as FOB Destination. Administrative requirements include electronic invoicing via the Internet Payment Platform and compliance with various federal regulations, including the Buy American Act and specific security prohibitions regarding telecommunications equipment. Proposals must be submitted to the USGS OAG Denver Acquisition Branch by September 11, 2026.
Ofc Of Acquisition Grants-Denver

POSTED

5 days ago

DEADLINE

in 2 days

AI Contract Overview

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SOFWERX, in collaboration with USSOCOM, DEVCOM CBC, DTRA, and the AIM GNOMES Team, is implementing a hybrid accelerator model to identify and develop technologies that provide awareness of biological agents and compounds in far forward, resource-limited environments. The initiative seeks to overcome current limiting factors in biological detection and identification to enhance warfighter capabilities in contested environments. This effort engages industry, academia, and national laboratories to accelerate the transition of disruptive technologies into the field through a structured multi-phase process involving collaboration events, technical submissions, and a competitive assessment event. The program follows a comprehensive timeline that included government-only and industry-wide collaboration events to define problem statements and refine operational requirements. Following a downselect process based on technical merit, selected participants pitch their solutions to a USSOCOM evaluation panel. Successful outcomes may lead to various agreement types, including Other Transaction Authority for research or prototypes, Cooperative Research and Development Agreements, prizes for technology achievements, or traditional FAR-based procurement contracts. Awardees may be required to comply with NIST SP 800-171 standards for protecting controlled unclassified information.

General Info

SOFWERX and USSOCOM are accelerating disruptive biological detection technologies for warfighter use.

Documents

2

AIM G-NOMES Collaboration Event (23 April 2024)

PDF, Low priorityindustry-day
Low

NIST SP 800-171

OCTET-STREAM

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Timeline

PhaseClosed
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Solicitation

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Organization & Contact Information

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AgencyDepartment Of Defense → US Special Operations Command (ussocom)
Contacts1 person available
OfficeN/A
Office AddressN/A
Contacts
Claire Hawley

Full Description

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Submissions Closed 09 June 2024 11:59 PM ET Purpose SOFWERX, in collaboration with the USSOCOM, U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC), the Defense Threat Reduction Agency (DTRA), and the Accelerator for Innovative Minds (AIM) Genomic Non-Specific Operational Matchmaking Enabled Systems (GNOMES) Team, will host a series of events leveraging their hybrid accelerator model to provide awareness of biological agents/compounds in a far forward, resource-limited environment. These events will provide opportunities for direct dialogue with Industry, Academia, Warfighters, and Government Subject Matter Experts (SMEs) to lower the barrier to working with the DoD and accelerate disruptive technologies and processing to the field. Background AIM is a collaborative initiative led by DoD in the CWMD and CBRNE space. The goal of AIM is to demonstrate an enduring Hybrid Accelerator model in coordination with Industry, non-traditional partners, and SMEs to develop technology, build networks/relationships, and develop processes targeting specific Warfighter problem spaces as identified by AIM government collaborators. AIM requests information from Industry, Academia, Laboratories, and non-traditional partners on approaches, products, and/or services to support CWMD technology requirements. Once these are reviewed, the collaborative DoD group intends to align transition pathways across the full technology maturation spectrum. Objective The Chemical and Biological Defense Program’s vision through AIM is to identify capabilities which provide insight of chemical and biological (CB) contested environments. The objective is to develop a system with maximum utility for the warfighter to overcome current limiting factors in providing awareness of biological agents/compounds in a far forward, resource-limited environment. Why You Should Participate USSOCOM seeks to enter into non-FAR or FAR-based agreements with Industry, Academic, and National Lab partners whose solutions are favorably evaluated by AIM GNOMES Subject Matter Experts (SMEs). As such, the follow-on Assessment Event (AE) is considered competitive and solutions will be evaluated independently of one another primarily for technical merit. This serves dually as notification of the intent to research the feasibility of an agreement under 10 U.S. Code, Section 4022 and/or Section 4022(f), and as notice of pre-solicitation activities IAW FAR 5.204. Event Timeline Completed Phase 1 - 23 January 2024 Government Only Collaboration Event (CE): SOFWERX will host a Government Only Collaboration Event (CE) with various stakeholders to focus on identification and prioritization of the limiting factors in providing awareness of biological agents/compounds in a far forward, resource-limited environment. During this event, Government stakeholders will identify and prioritize requirements and desirements for the biological detection and identification in austere and resource limited environments and will also identify current limitations with existing tools and ideate ways to fill capability gaps. Problem statement(s) will be developed to frame biological agent/compound detection and identification needs. Outcomes from the Government Only Collaboration Event will shape the Industry, Academia, and Laboratory Collaboration Event on/around 20 February. Request to attend Closed 09 January. Tentative Agenda All times listed are in ET 8:00 – 8:20: Participants arrive at SOFWERX 8:20 – 8:25: SOFWERX Welcome 8:25 – 8:45: Stakeholder Overview & Problem Set 8:45 – 9:45: Current Limitations Breakout 9:45 – 10:00: Break 10:00 – 11:00: Ways to Overcome Limitations Breakout 11:00 – 12:30: Lunch (on your own) 12:40 – 2:30: Problem Statement Development 2:30 – 2:45: Break 2:45 – 3:15: Problem Statement Briefs 3:15 – 3:30: Prioritization 3:30 – 3:45: Path Forward Note: Agenda is subject to change This event will be held in person at SOFWERX. Completed Phase 2 - 23 April 2024 Collaboration Event (CE): SOFWERX will host the Collaboration Event (CE) with Industry, Academic, and Laboratory partners focused on solutions for biological detection in austere and resource limited environments. During this event, Warfighters will interact with potential solution offerors and further communicate operational needs and desirements. Participation in this event is not mandatory, however, it is designed to provide insights to ensure potential offerors understand the problem set(s) fully and to increase the likelihood of matching their technologies with Warfighter needs. This CE is also an opportunity for attendees to meet and form partnerships that may provide a more comprehensive solution. If you do not wish to participate in the CE, you are free to submit your technology on/around 08 May for the AE. Request to attend the CE below, NLT 19 March. On or around 02 April 2024, SOFWERX will send confirmed registered persons event attendance information. Tentative Agenda All times listed are in ET 9:00-9:30: Attendees Check-In 9:45-9:50: SOFWERX Welcome Remarks 9:50-10:00: Stakeholder Remarks 10:00-10:15: Break 10:15-12:00: Problem Statement Round Robin 12:00-1:30: Lunch (On Your Own) 1:30-2:00: Large Group Q&A 2:00-2:30: Networking 2:30-2:45: Technologies, Techniques, and POCs Submissions 2:45-3:00: Wrap-Up and Follow-On Event Schedules/Q&A 3:00: Optional SOFWERX 101 & Tour Note: Agenda is subject to change This event will be held in person at SOFWERX. Completed Phase 3 - 16 May 2024 to 09 June 2024 Submissions to the Assessment Event (AE) Open: Interested respondents who could potentially provide solutions that meet the needs of USSOCOM are encouraged to submit their capability for USSOCOM review. To submit your technology for potential Phase 5 attendance, please review the assessment criteria and follow the submission instructions at the bottom of this webpage. Completed Phase 3a - 28 May 2024 Q&A Telecon: Interested offerors may participate in a virtual Q&A session to better understand the PM's specific technology objectives. The telecon will take place on 28 May from 2:00 - 3:00 PM ET. Completed Phase 4 - 10 June 2024 to 21 June 2024 Downselect: USSOCOM will downselect those respondents/submissions they feel have the highest potential to satisfy their technology needs. Favorably evaluated submissions will receive an invitation to attend the AE on/around 25 June. Completed Phase 5 - 09 July 2024 to 10 July 2024 Assessment Event (AE): During the AE, selected participants will be allotted a one-on-one session with the USSOCOM evaluation panel to pitch, demonstrate, and/or discuss their solutions. The forum will include a Q&A portion and discussions may continue outside of the event. Solution brief presentation guidelines will be outlined in the event invitation and solutions will be assessed according to the criteria in the link provided below. If the USSOCOM evaluation panel favorably evaluates a solution brief, negotiations for Phase 6 may immediately begin. Phase 6 - Path Forward: Successfully negotiated awards may fall under any combination of these categories: Business to business research and development agreement as a sub-award through the SOFWERX Partnership Intermediary Agreement (PIA) ( 15 U.S. Code Section 3715 ) OTA for research or prototype projects ( 10 U.S. Code Sections 4021 , 4022 ) An award under 10 U. S. Code, Section 4022 may result in the further award of a follow-on production agreement without additional competition based on successful prototype completion. The Government may make this follow-on production award based upon successful prototype criteria, which will be determined for each prototype project. Procurement for experimental purposes ( 10 U.S. Code Section 4023 ) Cooperative Research and Development Agreement ( 15 U.S. Code Section 3710a ) Prizes for advanced technology achievements ( 10 U. S. Code Section 4025 ) and/or prize competitions ( 15 U.S. Code 3719 ) FAR-based procurement contract NOTE: Awardees may need to be compliant with NIST SP 800-171 , Protecting Controlled Unclassified Information (CUI) in Non-Federal Systems and Organizations

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NAICS: 332999
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NAICS: 541715
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USSOCOM Open Call for Technical Experimentation 27-1: Special Operations Forces (SOF) Combat Diving (Diver Communications, Diver Propulsion, Underwater Interfaces) and Maritime Domain Situational Awareness Sensing Integration on USVs
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