Bio-Rad CFX Opus 96 Real-Time PCR System

The National Institutes of Health, through the Office of Laboratory Animal Welfare within the Department of Health and Human Services, has issued a Notice of Intent to award a Firm-Fixed-Price Purchase Order to Bio-Rad Laboratories, Inc. for the acquisition of one new, commercially available Bio-Rad CFX Opus 96 Real-Time PCR System. The equipment is required for the laboratory of Dr. Thomas Misteli located in the Center for Cancer Research, Laboratory of Receptor Biology and Gene Expression Branch, in Bethesda, Maryland. This system must function as a 96-well, five-color plus FRET, network-connected real-time PCR platform capable of supporting gene expression analysis, assay optimization, plate setup, data collection, statistical analysis, and graphing of results, with the necessary sensitivity, thermal performance, temperature gradient capability, compact design, and optical precision to support advanced chromatin and cancer research workflows. The solicitation number is 75N98026Q00493, posted on June 1, 2026, with a response deadline of June 10, 2026, at 11:00 p.m. EDT. Small businesses, including 8(a), service-disabled veteran-owned, HUBZone, small disadvantaged, veteran-owned, and women-owned entities, may submit written capability statements demonstrating their ability to meet the requirement by emailing david.shen@nih.gov, though the government retains sole discretion to determine whether to open the award to competition. No contract value, delivery timeline, or period of performance is specified, and while the procurement is structured as a sole-source purchase order, responses from small businesses may be considered. The contract will be delivered to the specified Bethesda location and no alternative suppliers have been indicated unless a competitive response is submitted and accepted.