Breaking Ground: The First Curative, Durable, Non-Surgical Therapy for Endometriosis

This contract seeks the development of innovative, non-surgical treatments for endometriosis, focusing on therapies that can reduce the size or deactivate endometrial implants, decrease inflammation caused by those implants, or prevent the growth and regrowth of lesions. The goal is to create the first curative and durable treatment that avoids invasive surgical procedures, representing a significant advancement in managing this chronic condition. The solicitation, issued by the Department of Health and Human Services through the Arpa-H agency, is designated as a Total Small Business Set-Aside, targeting small businesses with fewer than 500 employees. Responses to the contract solicitation are due by July 10, 2026, with the opportunity aiming to support projects that deliver breakthrough, non-surgical solutions to improve patient outcomes in endometriosis care.