Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)

The National Institutes of Health, under the Department of Health and Human Services, is soliciting applications through PAR-28-090 for the Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) programs. These programs are designed to provide administrative and shared research support, infrastructure, and expertise to enhance interdisciplinary HIV/AIDS research, specifically focusing on translational and implementation science and the Ending the HIV Epidemic Initiative. While CFARs provide comprehensive resources, D-CFARs are specifically intended to help recipients identify gaps and improve their competitiveness for future standard CFAR awards. The program is structured around various cores, including Administrative, Developmental, Advanced Technology, Clinical Science, and Implementation Science cores, as well as Scientific Working Groups. Applications are subject to a multi-stage review process involving scientific peer review for technical merit and a second-level review by a national Advisory Council or Board based on program priorities and fund availability. Applicants must be registered in SAM.gov and eRA Commons, with a limit of one application per institution. The submission requires detailed documentation, including SF424 forms and specific page-limited components for each core. Awardees must adhere to strict cybersecurity incident reporting requirements, notifying the agency within 48 hours of discovery, and must provide comprehensive biosafety and security plans if using Select Agents. The solicitation remains open for responses until May 25, 2029.