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This Presolicitation opportunity from Department Of Health And Human Services was posted on July 14, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Custom MHC Class II HLA-DP Xynapse and Dextramer R

Closed
75N98026Q00782Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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Solicitation # HT942727RE006
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DEADLINE

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The contract solicits the development of custom MHC Class II HLA-DP Xynapse and Dextramer reagents specifically for validating liver cancer neoantigens, targeting advanced immunological tools to enhance precision in cancer research. These reagents are critical for detecting and characterizing T-cell responses against neoantigens presented by HLA-DP molecules, which are essential in understanding immune recognition in hepatocellular carcinoma and other liver malignancies. The work requires precise molecular design, synthesis, and validation of reagents capable of high-affinity binding and specificity, ensuring reliable detection of rare antigen-specific T cells in patient samples. The project demands expertise in immunogenetics, protein engineering, and functional immune assays to meet rigorous performance thresholds. The solicitation, issued by the National Institutes of Health under the Department of Health and Human Services, is managed from Bethesda, Maryland, with a submission deadline of July 22, 2026. The NAICS code 813920 indicates the scope aligns with scientific research and development services, and the contract is open to all eligible vendors without specific set-asides. Patricia Haun serves as the primary point of contact for inquiries, and responses must be submitted through the SAM.gov portal. Successful applicants will deliver validated, ready-to-use reagents with full characterization data to support ongoing liver cancer immunotherapy research initiatives funded by the NIH.

General Info

Develop custom HLA-DP reagents to validate liver cancer neoantigens for immune response detection.

NAICS

813920 - Professional Organizations

Place of Performance

MD

Set-Aside

NONE

Documents

1
DOCX, Low priorityjustification-and-authorization
Low

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Timeline

PhaseClosed
Posted

Solicitation

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
Contacts1 person available
OfficeBETHESDA, MD, 20892, USA
Office AddressBETHESDA, MD, 20892, USA

Full Description

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Custom MHC Class II HLA-DP Xynapse and Dextramer Reagents for Liver Cancer Neoantigen Validation

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