Custom Peptide Synthesis and Conjugation Services

The contract involves the synthesis of custom peptides and their conjugation to dextramer platforms labeled with fluorescent tags such as phycoerythrin (PE), specifically for use in immune monitoring applications. The work requires precise chemical synthesis of peptides tailored to specific immunological targets, followed by their stable attachment to dextramer scaffolds to enable high-sensitivity detection of antigen-specific T cells. Barcode labeling is a critical component, allowing multiplexed tracking and identification of multiple peptide-MHC complexes within a single sample, which enhances the efficiency and throughput of immune response analysis. The project is intended to support advanced research tools used in immunology and vaccine development, particularly in the context of infectious disease and cancer immunotherapy studies. This subcontract is issued under the National Institutes of Health NIDA, part of the Department of Health and Human Services, and falls under NAICS code 325414 for pharmaceutical preparation manufacturing. The opportunity was posted on August 6, 2026, with a response deadline of August 13, 2026. There is no set-aside designation specified, and no physical place of performance or point of contact details are provided. The work is expected to be performed by a qualified vendor capable of meeting high-purity standards and regulatory compliance for research-grade reagents, with deliverables including fully characterized peptide-dextramer-fluorophore conjugates ready for downstream immune cell assays.