This Pre-Solicitation opportunity was posted on August 8, 2014. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Digital PCR System for Toxiocological and Toxicokinetic Studies of Xenobiotics

Awarded

N02RC43802-91Federal

Submission Closed08/22/2014, 04:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541711

New

Federal

MANAGE AND OPERATE THE NATIONAL RENEWABLE ENERGY LABORATORYThe Department of Energy, through the Golden Field Office, is forecasting a contract to manage and operate the National Renewable Energy Laboratory located in Colorado. This initiative falls under NAICS code 541711 and is currently associated with the incumbent contractor, Alliance for Energy Innovation, LLC. The opportunity is listed as a forecast with a posted date of October 25, 2026. Yolanda Dixon serves as the Small Business Program Manager and primary point of contact for this requirement.

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DEADLINE

Research Subaward / Collaborative Research PartnerThis subcontract establishes a collaborative research partnership to support prime contractors on research projects funded by the National Science Foundation and UK Research and Innovation, specifically under the Arts and Humanities Research Council. The selected partner is responsible for executing specialized research tasks, including data collection and analysis, following project-defined methodologies to solve specific research challenges and support planned outputs. Key deliverables include the provision of research data, detailed analysis reports, and contributions to final publications. To ensure compliance, all work must adhere to the NSF Grant Policy Manual and established UKRI funding norms. The engagement is categorized under NAICS code 541711, focusing on research and experimental development in the natural sciences and engineering.

Arts and Humanities Research Council (AHRC)

POSTED

DEADLINE

Research Collaboration and Laboratory AnalysisThe Research Collaboration and Laboratory Analysis subcontract is issued by the National Institute of Food and Agriculture under the Department of Agriculture. This agreement focuses on supporting grant recipients of the USDA-NIFA 1890 Capacity Building Grant Program through the execution of research tasks, data collection, and laboratory analysis. The scope of work includes conducting field trials and laboratory testing to meet specific scientific objectives, with required deliverables consisting of research data sets, technical reports, and peer-reviewed publications. Classified under NAICS code 541711, the opportunity was posted on September 3, 2026, with a response deadline of November 4, 2026. This subcontract is designed to provide essential technical and analytical support to ensure the successful completion of research goals within the specified grant program.

National Institute Of Food And Agriculture

POSTED

DEADLINE

Novel In-Situ Binder Chemistry DevelopmentThe NASA SBIR/STTR Program is seeking a subcontractor for the development of a novel in-situ binder chemistry designed for use on the Moon or Mars. The primary objective of this project is to create a binder sourced entirely from lunar or Martian regolith that can cure without the need for external energy input. The scope of work encompasses the initial formulation, lab-scale testing, and subsequent optimization of the chemistry to ensure viability for extraterrestrial construction. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate, specifically for firms with fewer than 500 employees. The work will be performed at the Kennedy Space Center, falling under NAICS code 541711 for research and development in biotechnology. The solicitation was posted on August 20, 2026, as part of NASA's efforts to advance sustainable infrastructure capabilities for deep space exploration.

NASA SBIR/STTR Program

POSTED

DEADLINE

High-Throughput Serology Assay DevelopmentThe contract requires the design, validation, and delivery of a high-throughput serology platform intended to match or surpass the performance of the current hemagglutination inhibition (HAI) assay used for influenza surveillance. The platform must be scalable and robust enough to support large-scale, rapid serological testing, ensuring accurate and consistent data collection for public health monitoring. Development must adhere to stringent performance benchmarks, with a focus on improving throughput, precision, and reproducibility across diverse influenza strains and sample types. This is a subcontract under the Department of Defense’s FA9000 AFGPO program, with performance centered at DWG. The North American Industry Classification System code 541711 indicates it falls under research and development in the physical, engineering, and life sciences. The solicitation was posted on June 15, 2026, and the work is expected to advance the DoD’s capability in infectious disease surveillance by replacing aging laboratory methods with a next-generation automated system. While no set-aside or point of contact details are provided, the project’s success is critical to maintaining national-level preparedness for seasonal and pandemic influenza threats.

POSTED

DEADLINE

Engineering & Scientific Research SupportThe contract entails providing engineering analysis, research and development, and technical support specifically focused on F-15 aircraft systems, encompassing avionics, propulsion, and weapons integration. The work involves activities such as modeling, simulation, and the formulation of test plans to support enhancements and maintenance of these complex systems. Issued by the Department of Defense under the NAICS code 541711, this subcontract titled "Engineering & Scientific Research Support" is designed to advance the technical capabilities and reliability of the F-15 platform. While certain logistical details like the exact place of performance and point of contact are not specified, the contract underscores a commitment to rigorous scientific and engineering efforts to ensure mission readiness and technological superiority for this key military asset.

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POSTED

DEADLINE

Technical Research and Analysis (Science & Technology Focus)This contract involves conducting advanced technical research across physical, engineering, and life sciences disciplines to support innovation and technology development within the defense sector. It is a subcontract opportunity issued by the Department of Defense through Washington Headquarters Services, aimed at advancing scientific and technological capabilities that bolster defense-related projects and initiatives. Designated as a Total Small Business Set-Aside under SBA regulations, the contract falls under NAICS code 541711, which pertains to research and development in the physical, engineering, and life sciences. The work is to be performed in Washington, reflecting a focus on high-impact, cutting-edge research that addresses critical defense challenges. This opportunity emphasizes the Department of Defense's commitment to engaging small businesses in strategic research efforts that drive forward defense technology and innovation.

Washington Headquarters Services

POSTED

DEADLINE

Vehicle Recompete: IGF::OT::IGF ID/IQ PARENT AWARD FOR PHARMACOLOGY AND TOXICOLOGY FOR… — INDEFINITE DELIVERY / INDEFINITE QUANTITY NIHNINDS1601This Indefinite Delivery/Indefinite Quantity parent award supports the Pharmacology and Toxicology for Therapeutics Program under the National Institutes of Health. The vehicle, identified by solicitation NIHNINDS1601, has an ordering period that extends through September 12, 2027. It is currently classified as a full recompete and is associated with two primary awards, HHSN271201600006I and HHSN271201600007I. There are currently 18 active task orders with a total combined value of over 18.7 million dollars. SRI International is the dominant incumbent, holding 15 orders totaling approximately 17.1 million dollars, with significant funding dedicated to continuous rodent and non-rodent pharmacokinetic assessments and GLP toxicology studies. Southern Research Institute holds the remaining three orders, valued at approximately 1.66 million dollars.

National Institutes of Health

POSTED

DEADLINE

Biotechnology and Life Sciences R&DThis subcontract, issued by the Department of Defense's AFRL Headquarters, focuses on biotechnology and life sciences research and development with an emphasis on defense-related applications. The scope involves advancing technologies such as bio-sensing, enhancing human performance, and developing medical countermeasures to support military readiness and resilience. The contract falls under the NAICS code 541711, which pertains to research and development in the physical, engineering, and life sciences. Although certain logistical details like specific location and points of contact are not provided, the work aims to contribute cutting-edge biotechnological innovations for national defense purposes. The solicitation was posted in January 2026, indicating a current opportunity for entities capable of delivering advanced R&D services in these specialized fields, collaborating closely with the Department of Defense to address evolving defense challenges through scientific and technological efforts.

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POSTED

DEADLINE

Green Chemistry R&D SupportThe Green Chemistry R&D Support subcontract, issued by the California Department of Toxic Substances Control, focuses on advancing the safety of nail product formulations. The primary objective is to assist manufacturers in researching and developing safer alternatives through the application of green chemistry initiatives, scientific collaboration, and rigorous pilot testing. This initiative falls under NAICS code 541711, indicating a focus on research and development in the physical, engineering, and life sciences. The project was posted on December 23, 2025, and aims to reduce hazardous substances in consumer products through targeted technical support and innovation.

California Toxic Substances Control, Department of

POSTED

10 months ago

DEADLINE

N/A

AI Contract Overview

The National Cancer Institute and the National Institute of Environmental Health Sciences intend to procure a digital polymerase chain reaction system from Bio-Rad Laboratories on a sole source basis. This firm fixed price contract is designed to support the Laboratory of Toxicology and Toxicokinetics in measuring low-expression genes to determine the mechanisms of effect of studied chemicals. The required system must be capable of detecting a single copy of a target sequence, differentiating between four and five copies, processing at least 150 samples per day, and including specific analysis software for data processing and baseline determination. The acquisition follows simplified acquisition procedures under FAR Part 13.106-1(b)(1) and is categorized under NAICS code 541712. Delivery of the equipment is required within 30 days of the award. While the government has identified the Bio-Rad QX 200 as the only instrument meeting these technical specifications, interested parties may submit capability statements for consideration until August 22, 2014. All potential contractors must maintain valid registration and certification in the System for Award Management to be eligible for the award.

General Info

NCI and NIEHS sole source procurement of Bio-Rad digital PCR system for toxicology.

Agency

N/A

Contract Value

$70,000

NAICS

541711 - Research and Development in Biotechnology

Place of Performance

Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Cancer Institute , NC, USA

Set-Aside

NONE

Awardee

BIO-RAD LABORATORIES, INC.

Award Issued Date

09/11/2014, 12:00:00 AM UTC

Documents

No documents available

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Timeline

PhaseAwarded

PostedAug 8

Presolicitation

AwardedSep 11

Contract was awarded

Submission Closed

08/22/2014, 04:00:00 PM UTC

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Organization & Contact Information

AgencyN/A

Contacts1 person available

OfficeN/A

Organization / Agency

N/A

Office AddressN/A

Contacts

Kelly L DempseyContracting Officer

contact@example.gov

+1 (555) 000-0000

Full Description

The National Cancer Institute (NCI), Center for Cancer Research (CCR), Basic Research Laboratory (BRL), in conjunction with National Institute of Environmental Health Sciences (NIEHS), plans to procure on a sole source basis a digital polymerase chain reaction (PCR) system from Bio-Rad Laboratories, 2000 Alfred Nobel Drive, Hercules, CA 94547. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b) (1) and is exempt from the requirements of FAR Part 6. The North American Industry Classification System code is 541712 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. Delivery shall be made within thirty (30) days after receipt of award. It has been determined there are no opportunities to acquire green products or services for this procurement. This acquisition is for the digital PCR system that is necessary for accurate measurement of low-expression genes to determine differences between experimental groups, and thus allow elucidation of the mechanisms of effect of the chemicals studied in the Laboratory of Toxicology and Toxicokinetics (LTT), a joint research endeavor of the National Cancer Institute/Center for Cancer Research and the National Institute of Environmental Health Sciences/Division of Intramural Research. The digital PCR system must have sufficient precision to differentiate between four (4) and five (5) copies of input target sequence, and be sensitive enough to detect a single copy. In addition, the PCR system must have sufficient throughput capability to measure at least 150 samples per day, and be compatible with commercially-available probe-based assays. Analysis software must be included which can be run in the user's desktop environment for run set-up and post-run processing of data, as well as provide for manual as well as automatic baseline determination. The QX 200 digital PCR system from Bio-Rad Laboratories is the only instrument on the market which can meet the above criteria. This notice is not a request for competitive quotation. However, if any interested party, especially small businesses, believes it can meet the above requirement, it may submit a capability statement, proposal, or quotation, which shall be considered by the agency. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 11:00 AM EDST, on August 22, 2014. All responses and questions must be in writing and emailed to Kelly Dempsey, Contracting Officer via electronic mail at contact@example.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the System for Award Management (www.sam.gov). Reference: N02RC43802-91 on all correspondence.