This Solicitation opportunity from Department Of Energy was posted on April 23, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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High-performance Optimized Recycled Nuclear Isotopes for Gen IV reactors (HORNIG)

Closed

DE-FOA-0003623Grant

Submission Closed08/06/2026, 01:30:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

New

Federal

Statistical ExpertiseThis small business set-aside subcontract, titled Statistical Expertise, supports prime contractors on NIH/NHGRI projects within the Department of Health and Human Services. The scope of work involves providing advanced statistical analysis and design for clinical research protocols, specifically requiring expertise in SAS or R for statistical programming, sample size calculations, and the interpretation of trial results. Key deliverables include validated statistical outputs, final analysis reports, and Statistical Analysis Plans. The performance of this contract takes place in Bethesda and is subject to strict HIPAA compliance, necessitating a mandatory Business Associate Agreement. Interested parties should note the response deadline of November 13, 2026, and the classification under NAICS code 541715.

National Institutes Of Health Olao

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Protocol Monitoring and Data Management SupportThis subcontract opportunity, titled Protocol Monitoring and Data Management Support, involves providing clinical trial protocol monitoring and research data management for prime contractors on NIH/NHGRI clinical research projects. The scope of work includes monitoring clinical research protocols, managing data services, and developing transition and startup documentation to deliver validated research datasets and monitored protocol reports. Performance will take place in Bethesda, and the project is categorized under NAICS code 541715. The contract is designated as a Total Small Business Set Aside for the National Institutes of Health under the Department of Health and Human Services. To ensure regulatory compliance, the selected provider must adhere to NIH ICO Information Security and Privacy certifications and execute a Business Associate Agreement for HIPAA compliance. Responses are due by November 13, 2026.

National Institutes Of Health Olao

POSTED

DEADLINE

Commercial Solutions Opening (CSO) for Space Domain Awareness (SDA) Solutions.

Solicitation # FA2518-25-S-C001

The United States Space Force, through the Space Acquisition and Integration Office, is executing a Commercial Solutions Opening (CSO) under solicitation FA2518-25-S-C001 to acquire innovative commercial technologies, products, and services that enhance Space Domain Awareness (SDA). The program focuses on improving the ability to detect, characterize, attribute, predict, and target activities in the space domain. This long-term mechanism remains open for five years and utilizes a multi-phase submission process consisting of an initial white paper and PowerPoint briefing, an optional pitch session, and a final full proposal package. Awards are made as FAR-based fixed-price contracts, and the government reserves the right to award some, all, or none of the proposed solutions. A primary focus of the current effort is Area of Interest (AOI) 2025_01, titled Advanced SDA Tools for Research and Analytics (ASTRA), which is a 100 percent small business set-aside. This specific AOI emphasizes research, development, and prototyping for scalable data management, modeling, and agile software prototyping, with an estimated combined funding pool of 1.5 million dollars across related AOIs and a period of performance not exceeding 12 months. Phase I submissions must be unclassified, though subsequent phases may require higher classification levels. Offerors must comply with NIST SP 800-171 and CMMC 2.0 requirements, particularly if handling Controlled Unclassified Information. Participation is restricted to U.S. entities due to national security and export control considerations.

FA2518 Ussf Spoc/saio

POSTED

DEADLINE

HYDROSPHERE, BIOSPHERE, & GEOPHYSICS (HBG) SUPPORT SERVICES II - FINAL REQUEST FOR PROPOSAL (FRFP)

Solicitation # 80GSFC27R0015

The National Aeronautics and Space Administration Goddard Space Flight Center is soliciting proposals for the Hydrosphere, Biosphere, and Geophysics (HBG) Support Services II contract, under solicitation number 80GSFC27R0015. This small business set-aside is a hybrid Indefinite Delivery Indefinite Quantity (IDIQ) contract with a five-year effective ordering period. The contract allows for the issuance of both Cost Plus Fixed Fee (CPFF) and Firm-Fixed Price (FFP) task orders to support science research and computing activities across various laboratories, including the Cryospheric Sciences, Ocean Ecology, Hydrological Sciences, Biospheric Sciences, Geodesy and Geophysics, and the Terrestrial Information Systems Laboratory. The primary objective is to develop and apply space, field-deployed, and laboratory-based technologies to address societal issues related to water resources, ecosystems, sea level change, and the Earth's magnetic and gravity fields. The scope of work encompasses scientific modeling, simulation, data assimilation, satellite instrument performance analysis, and the planning and execution of field campaigns. Performance will occur at the Goddard Space Flight Center and the contractor's facilities, with acceptance managed by the Contracting Officer or a designated representative. Award selection will be based on a tradeoff approach, prioritizing Mission Suitability as the most important factor, followed by Cost and Past Performance. Proposals must be submitted in four volumes, including a numerically scored Mission Suitability volume and a detailed Cost volume. Additionally, the contractor must adhere to strict security requirements, including the provision of a Cyber Supply Chain Risk Management plan and compliance with NDAA Section 889 regarding telecommunications and surveillance equipment.

NASA Goddard Space Flight Center

POSTED

DEADLINE

AN41--Pre-clinical Research: Behavioral Assessment

Solicitation # 36C24127Q0035

The Department of Veterans Affairs intends to award a single-source Blanket Purchase Agreement for pre-clinical research services focused on Traumatic Brain Injury and Posttraumatic Stress Disorder under the authority of FAR 13.106-1(b). The project, led by Dr. Wilder Doucette, aims to identify neural signatures and behavioral deficits associated with neurotrauma and psychological trauma to develop personalized interventions using brain stimulation and pharmacotherapy. The period of performance is five years, spanning from November 13, 2026, to November 12, 2031. Work will be split between the White River Junction VA Healthcare System and Mary Hitchcock Memorial Hospital, with approximately 75 percent of the activity occurring at the latter. Key deliverables include data sets and reports on behavioral deficits and neural activity biomarkers within six months, treatment utility reports within nine months, and a comprehensive summary of study findings within twelve months and annually thereafter. All personnel must maintain specific certifications, including CITI, Bioraft training, IACUC approval, and VA-Without Compensation research affiliate designations. The government retains unlimited rights to all deliverables and data produced under the contract. Prospective vendors must be registered in SAM and VetCert, and those claiming small business status must be verified by the Small Business Administration.

241-NETWORK Contract Office 01 (36C241)

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DEADLINE

Sources Sought: Domestically Produced Hand and Measuring Tools (ACC-DTA CSO Amend 40)

Solicitation # W912CH26S0001

The Army Contracting Command – Detroit Arsenal (ACC-DTA) Commercial Solutions Opening (CSO), solicitation W912CH-26-S-0001, serves as a rapid-acquisition gateway to transition cutting-edge commercial technologies into active defense programs. This vehicle supports a diverse customer base, including the Intelligence and Security Command (INSCOM) and six Portfolio Acquisition Executives, focusing on the development, integration, and sustainment of ground vehicle systems to enhance Army modernization and readiness. The CSO utilizes a streamlined, merit-based, multi-phased evaluation process consisting of solution briefs, presentations, and commercial solution proposals. Awards may be issued through 2028 via FAR Part 12 commercial procedures or non-FAR agreements, such as transaction agreements under 10 U.S.C. 4022 and Cooperative Agreements under 31 U.S.C. 6305. The solicitation encompasses various Areas of Interest (AoI) targeting critical capabilities, including the FALCONS prototype for long-range reconnaissance, TIGER Readiness for the Abrams Main Battle Tank engine supply chain, Counter-Unmanned Aircraft Systems (C-UAS) detection, and the Light Tactical Trailer Heavy Chassis (LTT-HC). Funding ceilings for specific prototypes, such as FALCONS, range from 24 million to 30 million dollars depending on the use of government-provided kits. Key requirements include strict adherence to the Buy American Act and Specialty Metals clauses, with a prohibition on reliance on adversarial foreign nations for critical minerals. Technical evaluations focus on mission viability, affordability, and schedule realism, while administrative requirements include SAM registration, a Unique Entity ID, and compliance with NIST SP 800-171 for handling controlled unclassified information.

POSTED

DEADLINE

Evaluations, Assessments, and Support Services (EASS)

Solicitation # 80LARC27R0003

Solicitation 80LARC27R0003 is a competitive small business set-aside for an Indefinite Delivery Indefinite Quantity (IDIQ) contract to provide Evaluations, Assessments, and Support Services (EASS) for the Science Office for Mission Assessments (SOMA) at NASA Langley Research Center. The contract supports the NASA Headquarters Science Mission Directorate by providing proposal and Phase A report evaluations, independent reviews of programs and investigations, and related technical analyses. The period of performance is scheduled from June 1, 2027, through May 31, 2032, with a minimum government obligation of 100,000 USD and a maximum contract value of 99,750,000 USD. Task orders under this IDIQ will be awarded on a firm-fixed-price basis. Award will be determined using a tradeoff approach where mission suitability and past performance are significantly more important than price. Mission suitability is evaluated on a 1,000-point scale focusing on the organizational conflict of interest plan, staffing approach, and management approach. Technical requirements include providing subject matter experts, task managers, editors, and data integrators who meet specific education and experience minimums. Due to the nature of the work, the contractor must maintain a TS/SCI facility clearance, ensure strict adherence to non-disclosure agreements, and comply with NASA cybersecurity and counterintelligence briefing requirements for foreign travel. Proposals must be submitted in four separate volumes via NASA's Enterprise File Sharing and Sync Box.

NASA Langley Research Center

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DEADLINE

Innovation & Technical Implementation PartnerThe Innovation and Technical Implementation Partner subcontract supports prime contractors on U.S. Department of State Jordan Private Sector Innovation Fund projects under the Bureau of Near Eastern Affairs. The selected partner is responsible for performing core technical activities, which include designing and executing proposed solutions and managing implementation plans. This work involves the use of specialized hardware, software, or agricultural and energy systems to deliver completed innovations, installed systems, or implemented services. All activities must be conducted in strict compliance with 2 CFR 200 administrative requirements. The opportunity is categorized under NAICS code 541715, with a response deadline set for September 30, 2027.

Bureau Of Near Eastern Affairs

POSTED

DEADLINE

Pre-clinical Treatment Evaluation ServicesThe Pre-clinical Treatment Evaluation Services subcontract involves providing administration and evaluation of novel interventions for prime contractors on Department of Veterans Affairs pre-clinical research projects. The scope of work focuses on implementing targeted treatment protocols for Traumatic Brain Injury and Post-Traumatic Stress Disorder to evaluate changes in neural and behavioral deficits, culminating in the delivery of treatment efficacy reports. To qualify for this role, personnel must hold a VA-Without Compensation research affiliate designation and obtain necessary approvals and certifications, including CITI training, Bioraft training, and IACUC approval. This opportunity is managed through the Department of Veterans Affairs Network Contract Office 01 under NAICS code 541715.

241-NETWORK Contract Office 01 (36C241)

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Neural Signature Assessment ServicesThis subcontract for Neural Signature Assessment Services supports prime contractors on Department of Veterans Affairs pre-clinical research projects. The primary objective is to analyze biological data and neural signatures from pre-clinical models to identify specific biological markers linked to Traumatic Brain Injury and Post-Traumatic Stress Disorder. The successful provider is responsible for delivering comprehensive data sets and neural signature analysis reports. To qualify for this engagement, personnel must hold a VA-Without Compensation research affiliate designation. Mandatory certifications and approvals include CITI training, Bioraft training, and IACUC approval. The project is managed under the Department of Veterans Affairs Network Contract Office 01 and falls under NAICS code 541715.

241-NETWORK Contract Office 01 (36C241)

POSTED

DEADLINE

Pre-clinical Behavioral Assessment ServicesThis subcontract for Pre-clinical Behavioral Assessment Services supports prime contractors on Department of Veterans Affairs research projects. The scope of work involves conducting behavioral testing and assessments on pre-clinical models to evaluate the efficacy of interventions specifically targeting Traumatic Brain Injury and Post-Traumatic Stress Disorder. The selected provider is responsible for delivering comprehensive behavioral assessment data and detailed reports. To qualify for this engagement, personnel must hold a VA-Without Compensation research affiliate designation. Mandatory certifications and approvals include CITI training, Bioraft training, and IACUC approval. The project falls under NAICS code 541715 and is managed through the Department of Veterans Affairs Network Contract Office 01.

241-NETWORK Contract Office 01 (36C241)

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.6 — Rural and Community Development

Solicitation # USDA-NIFA-TOPIC-8.6

The USDA SBIR/STTR Topic 8.6 solicitation, managed by the National Institute of Food and Agriculture, seeks to improve the quality of life in rural America through the creation and commercialization of science-based technologies. The program focuses on addressing critical economic and social challenges, requiring applicants to explicitly define the rural problem they intend to solve and how their technology will provide a solution. While not limited to agriculture, projects must include objectives to evaluate their impact on the environment, climate mitigation, or the socio-economic development of rural communities. This opportunity is a total small business set-aside for entities with fewer than 500 employees. The USDA is looking for a diverse portfolio of projects that balance high-risk, high-reward innovations with the practical application of existing technologies. Interested parties can find further details through the National Program Leader, Carlos Ortiz, or via the official NIFA website.

National Institute of Food and Agriculture

POSTED

2 days ago

DEADLINE

N/A

AI Contract Overview

The HORNIG program, under the ARPA-E Funding Opportunity Announcement DE-FOA-0003623, aims to advance the development of transuranic fuels from domestic fissile resources to strengthen U.S. nuclear energy security, reduce radioactive waste volumes, and diminish reliance on foreign fuel sources. This initiative supports coordinated research and development across fuel design, fabrication, testing, modeling, and qualification, with a focus on techno-economic analysis and deployment pathways to enable economic viability of advanced fuels for Generation IV reactors. Proposals must demonstrate transformative technology with high technical merit, clear performance targets, and robust risk mitigation strategies, evaluated primarily on impact (35%), scientific and technical merit (35%), management plan soundness (20%), and team qualifications (10%). Award decisions are based on a trade-off process favoring overall value over cost, with no use of lowest price technically acceptable evaluation. All work must occur within the United States, subject to Buy America provisions, and applicants must fully disclose foreign connections, affiliations with malign talent programs, and any use of generative AI in application preparation. Required documentation includes a detailed technical volume, SF-424 and SF-424A forms, biosketches, business assurances, and transparency disclosures, all submitted electronically via the ARPA-E eXCHANGE portal by the May 28, 2026 deadline. Successful recipients must maintain data archives for long-term usability, comply with research security training, enforce confidentiality agreements, and adhere to strict marking protocols for proprietary information, including labeling every confidential page with a specific disclaimer. Applicants must be registered in SAM.gov and possess a Unique Entity Identifier; small businesses may qualify under SBA size standards, though no other socioeconomic set-asides are specified. The anticipated project period runs from December 2026 to December 2029, with potential for renewal based on performance and funding availability.

General Info

ARPA-E funds research to develop cost-effective recycled transuranic fuels for Gen IV nuclear reactors.

Agency

Department Of Energy → Advanced Research Projects Agency-Energy

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

DE-FOA-0003623 HORNIG ARPA-E Funding Opportunity

nofo

High

HORNIG_CP_Template_Category_A Concept Paper Template

concept-paper-template

High

HORNIG_CP_Template_Category_B Concept Paper Template

concept-paper-template

High

ARPA-E Summary for Public Release Template

template

Low

ARPA-E Transparency of Foreign Connections Disclosure and Certification Form

other

Low

Business Assurances & Disclosure Form - Download Error

other

Low

Category A Full Application Technical Volume Template

other

Low

Category A_ SF-424A _ Budget Justification Workbook

other

Low

Category B Full Application Technical Volume Template

other

Low

Category B_ SF-424A _ Budget Justification Workbook

other

Low

Full Application Summary Slide Template

other

Low

HORNIG Concept Paper Summary Slide

other

Low

HORNIG Concept Paper Template - Category A

other

Low

HORNIG Concept Paper Template - Category B

other

Low

HORNIG Full Application NOFO - Download Error Page

other

Low

HORNIG LCOF Tool - Download Error Page

other

Low

Replies to Reviewer Comments Template

other

Low

SF-424.html

other

Low

HORNIG_CP_LCOF_Tool.xlsx

HORNIG_CP_Summary_Slide_Template.pptx

SF-424: Application for Federal Assistance and SF-LLL: Disclosure of Lobbying Activities

AI Contract Breakdown

Uniform Contract Format

Timeline

1 update

PhaseClosed

PostedApr 23

Solicitation

Notice updatedApr 23

Response deadline changed from May 28, 2026 to Aug 6, 2026. The notice description changed.

Response DeadlineAug 6

Deadline has passed

Submission Closed

08/06/2026, 01:30:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Energy → Advanced Research Projects Agency-Energy

Contacts2 people available

OfficeUSA

Organization / AgencyDepartment Of Energy → Advanced Research Projects Agency-Energy

Office AddressUSA

Contacts

ARPA-E eXCHANGE Help

contact@example.gov

ARPA-E Contracting Officer

contact@example.gov

Full Description

NOFO Modification 01 posted and Encourage/Discourage letters sent July 7, 2026.

This funding opportunity supports the development of transuranic (TRU) fuels from a largely untapped, domestic fissile resource found across U.S. inventories. TRU fuels could expand the nation’s nuclear fuel supply while reducing the volume of radioactive waste. Establishing TRU fuels as an economic source of energy will bolster American industry, energy dominance, and national security by:

Strengthening fuel supply chains for nuclear reactors
Reducing reliance on foreign sources
Advancing American leadership in critical technologies
Supporting long-term deployment of new nuclear power plants

High-performance Optimized Recycled Nuclear Isotopes for Gen IV reactors (HORNIG) will fund coordinated research and development efforts spanning fuel design, fabrication, testing, modeling, and qualification, along with analysis of cost, impact, and deployment pathways.

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