High-Specificity Capture Ligand Development

This contract focuses on the development and testing of synthetic or engineered ligands, including aptamers, peptides, or molecularly imprinted polymers, for the selective binding of a variety of large biomolecules found in complex feedstocks. The goal is to create high-specificity capture ligands capable of targeting diverse biomolecular structures with precision. This work involves both the design and experimental validation phases to ensure the effectiveness of the ligand candidates. Issued by the Defense Advanced Research Projects Agency under the Department of Defense, the contract is classified as a subcontract under the NAICS code 541711, which pertains to research and development in biotechnology. Although specific location details for performance and points of contact are not provided, the solicitation was posted on May 15, 2026, with responses due by June 8, 2026. The contract represents an opportunity to contribute to advanced molecular capture technologies with potential applications in defense-related biomolecular processing.