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This Government Contract opportunity from Department Of Health And Human Services was posted on May 7, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Illumina Dragen Server

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75N98026Q00331Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

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The National Cancer Institute (NCI) Lab of Pathology under the National Institutes of Health (NIH) is seeking to procure an Illumina Dragen server, a specialized bioinformatics data processing system designed for clinical Next Generation Sequencing (NGS). This on-premises hardware solution, exclusively sourced from Illumina Inc., will support highly accurate and comprehensive gene and sequencing analysis using Illumina’s proprietary bioinformatics pipelines pre-installed on the server, including Dragen TruSight Oncology 500 (TSO500) and its related assay versions. The server will streamline secondary analysis of data generated from the Lab’s current and upcoming clinical assays, scheduled to begin in July 2026, and integrate with the NIH Biowulf cluster per a signed memorandum of understanding between NCI and NIH CIT. The Dragen server offers significant computational speed and efficiency improvements, leveraging Illumina-optimized software and hardware to accelerate input/output processing, ultimately enabling full whole gene sequencing capabilities within the institute. The server can be hosted locally or on the NCI cloud, interfacing with existing instruments and Helix drives, though certain data storage configurations require mapped drives for proper input. Illumina will provide around-the-clock support, including hardware replacement, labor, and software upgrades, reflecting the sole source nature of this procurement under FAR 6.302. The contract, designated under solicitation number 75N98026Q00331, is intended for negotiation with Illumina Inc. as the only qualified supplier, with a response deadline set for May 21, 2026. The overall aim is to enhance NCI’s clinical sequencing infrastructure with cutting-edge, manufacturer-supported technology.

General Info

NCI procures Illumina Dragen server for clinical NGS, exclusive sourcing, support, July 2026 start.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

334516 - Analytical Laboratory Instrument Manufacturing View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(1)

SOW for Illumina DRAGEN Server v4 Purchase and Maintenance

DOCXsow

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Timeline

PhaseClosed
Posted

special-notice

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeBethesda, MD, 20892, US
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressBethesda, MD, 20892, US

Full Description

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The National Institutes of Health – NCI Lab of Pathology intends to solicit the services of a contractor to provide Dragen (Dynamic Read Analysis for GENomics) Sever from Illumina for on-premises solution for highly accurate and comprehensive gene and sequencing analysis.  The server is user-friendly hardware to operate analysis on the server that does not require sample pooling and indexing and can only be sourced from the manufacturer, Illumina, Inc.



The main objective is to buy the bioinformatics data processing “DRAGEN” server (IT hardware) provided by the manufacturer (Illumina Inc.) for clinical Next Generation Sequencing. The DRAGEN server will have pre-installed Dragen TruSight Oncology 500 (TSO500) and Dragen TSO500 ctDNA analysis software support secondary analysis for the data generated by the Lab’s current clinical TSO500 assay, and new TSO500 v2, TSO500 HRD add-on assay, TSO500 ctDNA assay.  The lab plans to start new TSO500 assays in July 2026. All new TSO500 assays come with Illumina’s proprietary bioinformatics pipeline that is only available on DRAGEN server. The server will be mounted on NIH Biowulf cluster by the NIH CIT team (a MOU has been signed between NCI and CIT).



This server comes with bio-informatics pipeline from Illumina which is optimized and runs on DRAGEN hardware. Accelerates IO process and speeds up the compute time and will eventually be used for full whole gene sequencing within the institute.  It’s possible to host the server locally or on the (NCI) loud.


Existing LP pipelines are already connected to Helix drives and use BioWulf.  This needs storage drives mapped. The instrumentations are connected to Helix drives. The raw data drive cannot be mapped with a service account to Helix drive. The input to DRAGEN should be from a drive that’s already mapped to a sequencer.  The vendor will provide 24/7 support both remotely and locally and replace parts and provide labor and software upgrades using the exclusive hardware/software supplies/services which makes this procurement a true sole source requirement.



This proposed procurement is for supplies for which the government intends to solicit and negotiate on a sole source basis under the authority of FAR 6.302 to Illumina Inc., located at 5200 Illumina Way San Diego CA 92122-4616. In order to comply with the requirements in this Special Notice, the responses should be based on our interpretation of the general requirements provided above.



The proposed contract action is for a continuation of similar supplies which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested persons may identify their interest and capability to respond to the requirement or submit quotations. This notice of intent is not a request for competitive quotes. However, all quotes received within the time and date of publication of this notice will be considered by the Government. A determination by the Government not to compete with this proposed contract based upon responses to this notice is solely within the discretion of the Government.