This Government Contract opportunity from Department Of Health And Human Services was posted on May 29, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Metabolic Stability and ADME Profiling

Closed

Federal

Submission Closed06/08/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541380

New

SLED

Intelligent Compaction (IC) ServicesThis contract requires the provision and operation of an Intelligent Compaction (IC) system during asphalt placement projects in Sequatchie. The IC system must monitor compaction in real time, producing color-coded maps that visually represent the compaction progress and quality. Additionally, the collected data is required to be uploaded daily to cloud storage to ensure compliance with Tennessee Department of Transportation (TDOT) standards and facilitate ongoing project oversight. The solicitation, identified under the NAICS code 541380, is a subcontract opportunity issued by TDOT with a response deadline of June 26, 2026. Although specific organizational qualifications or set-aside provisions are not mentioned, the contractor must have the capability to deliver both the technology and operational expertise to support advanced asphalt compaction monitoring. The place of performance is Sequatchie, Tennessee, emphasizing the local application of this technology in TDOT infrastructure projects.

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Geotechnical Laboratory Soil TestingThe contract involves conducting comprehensive geotechnical laboratory testing on soil samples, including analyses such as grain size distribution, Atterberg limits, moisture content, density, swell potential, and soil classification following USCS and AASHTO standards. These tests are critical for assessing soil properties and behavior, supporting infrastructure projects managed by the Tennessee Department of Transportation (TDOT). The work is designated as a subcontract under NAICS code 541380, which pertains to testing laboratories. The contract is posted with a deadline for responses on June 26, 2026, and the laboratory testing will be performed primarily in the Maury area. No specific set-aside designation or organization type is specified. The solicitation is managed by TDOT, and the project documentation and proposal submission details are accessible through the TDOT bidding platform.

POSTED

DEADLINE

Construction Materials Testing and InspectionThis contract involves subcontracting third-party testing and inspection services for construction materials, specifically concrete and structural steel, to ensure compliance with the standards set by the Tennessee Department of Transportation (TDOT) and CSX. The primary focus is on verifying the quality and safety of these materials used in construction projects located in Sullivan, Tennessee. The contract falls under the NAICS code 541380, which covers testing laboratories, and it was posted and set with a response deadline on June 26, 2026. The Tennessee Department of Transportation is overseeing the contract, although specific details about the office address and point of contact are not provided. Interested parties are directed to submit proposals by the deadline through the TDOT bidding portal. This subcontract aims to support the integrity and regulatory compliance of infrastructure projects in the region.

Tennessee Department of Transportation

POSTED

DEADLINE

Third-Party Testing and Quality AssuranceThis contract involves performing independent testing and quality assurance services for materials and construction processes related to a project overseen by the Tennessee Department of Transportation (TDOT). The contractor is responsible for conducting thorough tests and delivering detailed reports within specified timelines to CSX for evaluation and approval. This ensures compliance with required standards and supports the overall integrity and safety of the construction work. The solicitation, titled "Third-Party Testing and Quality Assurance," is a subcontract opportunity identified by the NAICS code 541380, which pertains to testing laboratories. The work is to be performed in Davidson, Tennessee. Proposals were due on June 26, 2026, aligning with the posted date, indicating a tight response window. The contract emphasizes the importance of independent verification to maintain quality control throughout the construction process.

POSTED

DEADLINE

Intelligent Compaction (IC) Monitoring and ReportingThe contract involves providing real-time monitoring and reporting of compaction data during Hot Mix Asphalt (HMA) paving operations using Intelligent Compaction (IC) certified equipment. The key requirement is the integration of this data with the Tennessee Department of Transportation’s (TDOT) Electronic Technical Automation System (ETAS) to ensure seamless data exchange and enhanced project oversight. The subcontract focuses on the use of advanced technology to improve paving quality and operational efficiency. This opportunity is issued by the Tennessee Department of Transportation, with the place of performance specified as Grundy. The contract is categorized under NAICS code 541380, which relates to testing laboratories, indicating a technical and specialized service scope. The solicitation and response deadlines both fall on June 26, 2026, emphasizing prompt submission from interested subcontractors. Overall, this contract is targeted at firms equipped with IC technology and capable of integrating their systems with TDOT’s platforms to support infrastructure projects.

Tennessee Department of Transportation

POSTED

in 10 days

DEADLINE

in 10 days

AI Contract Overview

This contract involves conducting in vitro ADME studies focused on evaluating drug candidates' metabolic stability and pharmacokinetic properties. Specifically, it requires performing assays such as microsomal stability, hepatocyte clearance, and CYP450 enzyme inhibition to determine how the drug candidate is metabolized and cleared in the body, essential factors for assessing its potential viability as a therapeutic agent. The work is to be carried out as a subcontract by the National Institutes of Health under the Department of Health and Human Services, with the place of performance located in Bethesda, zip code 20892. The contract, titled "Metabolic Stability and ADME Profiling," was posted on May 29, 2026, and has a response deadline of June 8, 2026. It falls under the NAICS code 541380, indicating research and development services in biotechnology. The work's primary goal is to provide critical ADME data that will guide drug development decisions based on metabolic behavior and interaction with key enzymes involved in drug metabolism, contributing to the overall assessment of drug safety and effectiveness.

General Info

Conduct in vitro ADME studies assessing metabolic stability, clearance, and CYP450 inhibition for drug candidates.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541380 - Testing Laboratories and ServicesView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PhaseClosed

PostedMay 29

subcontract

Response DeadlineJun 8

Deadline has passed

Submission Closed

06/08/2026, 09:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

Office AddressN/A

ContactsNo contact information available

Full Description

Conduct in vitro ADME studies including microsomal stability, hepatocyte clearance, and CYP450 inhibition to assess drug candidate viability.