Miscellaneous / Gene Synthesis

This is a combined Synopsis/Solicitation/Notice of Intent for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are not being requested and a written solicitation will not be issued for the solicitation number NIAID-NOI-12023 a Notice of Intent. The incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2005-54 dated November 2, 2011. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is a small business set-aside. The associated North American Industry Classification System (NAICS) Code is 541380, which has a size standard 12.0 in millions of dollars. The National Institute of Allergy and Infectious Disease (NIAID) intends to procure Subcloning, Mutagenesis, Gene Synthesis and Plasmid Production services from GeneImmune Biotechnology. The services are to include the following items: (1) GI-TZ01, Mutagenesis including insert up to 60bps, qty-14, (2) GI-TZ02, 1mg DNA Prep (MaxiPrep), qty-10, (3) GI-TZ03, 5mg DNA Prep (MegaPrep), qty-25, (4) GI-TZ04, 10mg DNA Prep, qty-5, (5) GI-TZ05, Regular Gene Synthesis, base, qty-2000, (6) GI-TZ06, Mutagenesis, 1mg, DNA (MaxiPrep), qty-71, (7) GI-TZ07, Subcloning, 1mg, DNA (Maxiprep), qty-45, (8) GI-TZ08, Subcloning/Overlapping PCR, qty-10, (9) GI-XW02, Subcloning, qty-10, and (10) GI-XW00, Gene Synthesis, qty-1. The GeneImmune Biotechnology is to perform site directed mutagenesis and subcloning to produce megaprep (at least 5mg) or maxiprep (1-2 mgs) of column purified plasmid DNA. The plasmid DNA will be evaluated for purity, quantified, and verified by single-pass sequencing prior to shipping. In addition, bacterial glycerol stocks will be stored on-site for 1 year for additional troubleshooting services if needed. GeneImmune Biotechnology has been providing this service to NIAID and changing vendors at this time could be detrimental to the results of the experiments facilitating the development of vaccines. This is a standing order for one year from date of award. Delivery is to Bethesda, Maryland, 20892. The following factors shall be used to evaluate offers: 1) capability to meet salient characteristics, 2) price, and 3) delivery. The government will award a fixed price purchase order to the responsible contractor. The FOB terms are "Destination" and Net 30. FAR provisions and clauses that apply to this acquisition: FAR 52.212-1, Instructions to Offerors, Commercial Items; FAR 52.212-2, Evaluation - Commercial Items; FAR 52.212-3, Offeror Representations and Certifications - Commercial Items; FAR 52.212-4, Contract Terms and Conditions - Commercial Items; FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes of Executive Orders - Commercial Items; and FAR 52.232-33 Payment by Electronic Funds Transfer-Central Contractor Registration (Oct 2003). In order to be considered for an award, an Offeror must have completed the online electronic Representations and Certifications located at http://orca.bpn.gov/ in accordance with FAR 4.1201 (a). By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the CCR at www.ccr.gov prior to award during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation. [Note: Lack of registration in the Central Contractor Registration will make an offeror ineligible for award.] All responsible sources may submit an offer that will be considered by the Agency. Offers must be submitted no later than 5:00 P.M. Eastern Standard Time on Friday, December 23, 2011. For delivery of responses through the Postal Service, the address is NIH/NIAID/AMOB, 10401 Fernwood Drive, Room 2NE52E, MSC 4811, Bethesda, Maryland 20892-4811. E-mail and Fax submissions are not authorized. Request for information concerning this requirement are to be submitted in writing, and can be faxed to +1 (555) 000-0000, or e-mail to contact@example.gov. It is the vendor's responsibility to confirm receipts of all quotations and/or questions by the closing date of this announcement by contacting Mr. Terry Knight at +1 (555) 000-0000. Collect calls will not be accepted.