NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01 Clinical Trial Not Allowed)

The National Institutes of Health (NIH) issued solicitation PAR-27-051 to provide the scientific community with access to biospecimens from the Adolescent Brain Cognitive Development (ABCD), HEALthy Brain and Child Development (HBCD), and Population Assessment of Tobacco and Health (PATH) studies. This initiative utilizes the X01 Resource Access Award mechanism to support research into genetic and environmental factors affecting health and disease, with a high priority placed on substance use, prevention, treatment, and tobacco regulatory science. Specifically, NBDC priorities include genomics, epigenetics, inflammation, stress, proteomics, neurotoxicants, the microbiome, and nutriture. This opportunity provides no federal funding; applicants are responsible for all research and distribution costs and must enter zero dollars for all funding requests. Applications are evaluated by an internal NIDA group based on scientific and technical merit, significance, and relevance to program priorities. Required documentation includes confirmation of biospecimen availability, active SAM and eRA Commons registrations, and IRB determination documentation if the research involves human subjects. Awardees must adhere to strict data use certifications and cybersecurity guidelines, including a requirement to report security incidents to the HHS within 48 hours of discovery.