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Notice of Intent to Sole Source - Custom Commercial Aptamer Procurement

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PANAPG-26-P-0000-051608Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The U.S. Army Contracting Command Aberdeen Proving Ground Edgewood Division intends to award a sole source, firm fixed price contract to Aptagen LLC for the custom synthesis, purification, quality control, and delivery of DNA, RNA, and peptide aptamers. These materials are critical for diagnostic assay development, biosensor research, and chemical and biological defense platforms supporting the DEVCOM Chemical Biological Center. To meet strict technical requirements, the aptamers must undergo denaturing Polyacrylamide Gel Electrophoresis purification, as standard commercial HPLC or cartridge methods are deemed unacceptable. The vendor is required to provide double tier empirical quality control for every delivery using ElectroSpray Ionization Mass Spectrometry and 10 percent Urea Gel dPAGE analysis. This notice of intent is not a request for competitive quotations, but the government will review responses submitted to the designated contracting officials by September 1, 2026. The procurement falls under NAICS code 541715 and will be performed in Maryland.

General Info

Army sole source contract to Aptagen LLC for custom DNA, RNA, and peptides.

Agency

Department Of Defense → Department Of The ArmyView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

MD, 21010, USA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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special-notice

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Organization & Contact Information

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AgencyDepartment Of Defense → Department Of The Army
Contacts2 people available
OfficeN/A
Organization / Agency
Department Of Defense → Department Of The Army
View Agency Profile
Office AddressN/A
Contacts
Nicholas Granata Jr
contact@example.gov
Sammy Solo
contact@example.gov

Full Description

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The U.S. Army Contracting Command – Aberdeen Proving Ground (ACC-APG), Edgewood Division intends to issue a Firm Fixed Price award on a sole source basis in accordance with Revolutionary Federal Acquisition Regulation Overhaul (RFO) FAR 6.103-1 to support the U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) and their requirement for a mission-critical, continuing requirement for the custom synthesis, purification, quality control, and delivery of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and peptide aptamers, with or without chemical modifications  delivered in lyophilized form. These aptamers serve as foundational biological recognition elements in diagnostic assay development, biosensor research, and chemical/biological defense mission-support platforms.


The synthesized aptamers will undergo denaturing Polyacrylamide Gel Electrophoresis (dPAGE) purification. Standard commercial HPLC or cartridge purification is technically unacceptable.


The vendor will provide empirical sequence-verification data using both ElectroSpray Ionization (ESI) Mass Spectrometry and 10% Urea Gel dPAGE analysis with every delivery order (Double-Tier Empirical Quality Control).


The intent is to award this contract to Aptagen, LLC., CAGE Code 436H7.  Aptagen LLC. is located at 250 North Main Street, Jacobus, PA 17407.  At this time, it is the Government’s understanding that no other contractor is capable of supplying the required aptamers.


This notice of intent is not a request for competitive quotations; however, all responses received within seven (7) days of the issuance of this notice will be reviewed accordingly by the Government. Any response should be emailed to Contract Specialist, Sammy Solo at sammy.b.solo.civ@army.mil and Contracting Officer, Nicholas Granata Jr. at nicholas.granata.civ@army.mil by 12:00 pm EST on 01 September 2026.


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