This Government Contract opportunity from Department Of Defense was posted on August 25, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to Sole Source - Custom Commercial Aptamer Procurement

Closed

PANAPG-26-P-0000-051608Federal

Submission Closed09/01/2026, 04:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

New

Federal

U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) Organic Industrial Base (OIB) Modernization Commercial Solutions Opening (CSO)

Solicitation # W911PT26SC001

The U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) has issued solicitation W911PT26SC001, a Commercial Solutions Opening (CSO) authorized under the National Defense Authorization Act for Fiscal Year 2026 and DFARS Subpart 212.70. This competitive solicitation is open until September 30, 2027, and is designed to acquire innovative commercial products, technologies, and services to modernize the Army's Organic Industrial Base. The scope focuses on integrating manufacturing resources, linking legacy analogue systems with digital systems, and expanding modeling and simulation to enhance the delivery of materiel solutions. The CSO targets both traditional and non-traditional business entities, including small businesses and foreign-owned firms, provided they maintain an active System for Award Management (SAM) profile and a Unique Entity ID. The acquisition process follows a multi-phased approach consisting of a written solution brief, an optional presentation or pitch, and a final Request for Commercial Solution Proposal (CSP). Evaluation is based on responsiveness, technical merit, uniqueness, and price reasonableness. Successful responses may result in fixed-price contracts awarded under FAR Part 12 Commercial Item Procedures. Current Areas of Interest (AoIs) include advanced cannon technology, electrical infrastructure improvements at Building 120, chromium facility conversion, automated manufacturing for minor components, automated cooling tower treatments, advanced CNC vertical turning lathes, and advanced tooling for radial forging. Performance is primarily located at Watervliet Arsenal and Benet Laboratories, with a general period of performance not to exceed 12 months unless otherwise specified.

POSTED

DEADLINE

"Provide specialized piping expertise overseeing the Craft Labor/Corrosion Control subcontractor for field modifications at KSC including but not limited to fabrication and installation of piping spool pieces, piping & tubing supports, flared & welded tub

Solicitation # 80NSSC26945986Q

NASA Shared Services Center

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Scientific Data Management and Publication SupportThe Scientific Data Management and Publication Support subcontract, issued by the National Institutes of Health under the Department of Health and Human Services, focuses on the dissemination of data, tools, and technologies for prime contractors involved in NIDCD medical research projects. The selected provider will manage resource sharing between laboratories and the NIDCD, assist in the preparation of scientific publications, and implement NIH Data Management and Sharing plans. These tasks must be executed using statistical software and secure data repositories while maintaining strict adherence to NIH cybersecurity guidelines. The primary deliverables for this engagement include the provision of disseminated data sets and the completion of published research papers. This opportunity falls under NAICS code 541715 and has a response deadline of March 5, 2027.

National Institutes Of Health

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Human Temporal Bone and Fresh Ear Tissue Processing LaboratoryThis subcontract for the National Institutes of Health involves the receiving and processing of human temporal bones and fresh ear tissue to support research network projects for the NIDCD. The selected provider will be responsible for obtaining specimens from the National Hearing and Balance Organ Donor Program, processing inner and middle ear tissues, scanning slides, and summarizing donor medical records. Final deliverables include the processed specimens, high-resolution scanned images, and comprehensive annotated data. To execute these tasks, the contractor must possess specialized high-resolution slide scanning equipment and maintain strict biohazard containment protocols. Additionally, the provider is required to maintain an active IRB certification throughout the duration of the project. This effort falls under NAICS code 541715 and is managed under the Department of Health and Human Services.

National Institutes Of Health

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Coordinating Center for National Resource Network for the Study of Human Auditory and Vestibular Disorders (U24 Clinical Trial Not Allowed)

Solicitation # RFA-DC-28-002

Solicitation RFA-DC-28-002 is a Notice of Funding Opportunity from the National Institutes of Health, specifically the National Institute on Deafness and Other Communication Disorders, to establish a Coordinating Center for the NIDCD National Human Ear Resource Network. This collaborative network provides human inner and middle ear tissues to researchers for basic and clinical studies aimed at advancing the treatment of auditory and vestibular disorders. The Coordinating Center is responsible for maintaining network cohesiveness through the planning of workshops, symposia, and regular meetings, providing updates to laboratories, and managing communication with the public and scientific community regarding tissue donation. The maximum project period is five years, with a budget limit of 200,000 dollars in direct costs per year. Applicants, including for-profit organizations and small businesses, must maintain active registrations in SAM, eRA Commons, and Grants.gov. Proposals are evaluated based on the significance of the proposed center and the qualifications of the investigators, with additional reviews for human subject protections, inclusion policies, and the use of vertebrate animals. Key requirements include a structured Data Management and Sharing Plan and adherence to cybersecurity guidelines, including a 48-hour incident reporting window. The application process is entirely electronic and requires several standard PHS and SF424 forms, with a response deadline of March 5, 2027.

National Institutes Of Health

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National Resource Network for the Study of Human Auditory and Vestibular Disorders (U24 Clinical Trial Not Allowed)

Solicitation # RFA-DC-28-001

Solicitation RFA-DC-28-001 is a Notice of Funding Opportunity issued by the National Institutes of Health under the Department of Health and Human Services to support the NIDCD National Human Ear Resource Network. The objective is to maintain a collaborative network of laboratories that serve as a national technological resource, providing human inner and middle ear tissues to researchers for basic and clinical studies to advance the treatment of auditory and vestibular disorders. The scope of work includes processing human temporal bones from the National Hearing and Balance Organ Donor Program, uploading images and medical data to EarBase, sharing gene-expression data via the gEAR repository, and providing technical instruction to increase the number of skilled researchers in the field. The NIDCD intends to commit 3.6 million dollars in FY 2028 to fund up to six awards, with a maximum project period of five years. Individual awards are limited to 450,000 dollars in direct costs per year, with an additional 150,000 dollars available for specific subawards. Applications are due on March 05, 2027, and November 01, 2027, with staggered start dates ranging from July 2027 to July 2028. Evaluation is based on the experience of the investigators, the adequacy of the institutional environment, and the protection of human subjects. Applicants must maintain active SAM registration and a Unique Entity Identifier, and they must provide a Data Management and Sharing Plan and a Material Transfer Agreement. Compliance with the Cybersecurity Act of 2015 is required, including the development of an incident response plan and notification of cybersecurity incidents within 48 hours of discovery.

National Institutes Of Health

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Silviculture Growth & Yield Modelling SpecialistThe Silviculture Growth and Yield Modelling Specialist subcontract supports prime contractors on projects for the Province of British Columbia's Ministry of Forests. The selected specialist will perform advanced statistical analysis and growth and yield modelling, specifically utilizing the Mixedwood Growth Model to establish stocking standards for conifer, broadleaf, mixedwood, and successional forests. A primary objective of the role is the creation of algorithms designed to project stand attributes based on data gathered from free growing surveys. Candidates must possess advanced proficiency in statistical analysis software and extensive expertise with the Mixedwood Growth Model to successfully deliver the required projection algorithms and modelled results. This opportunity was posted on October 19, 2026, with a response deadline of October 29, 2026.

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Mental Health Screening Tool Array DesignThis subcontract, titled Mental Health Screening Tool Array Design, involves providing clinical content and validated screening tools to prime contractors working on Illinois State Board of Education projects. The primary objective is to develop specialized tool arrays capable of identifying childhood mental health challenges related to internalizing, externalizing, and trauma. To ensure clinical efficacy and legal compliance with Public Act 104-0032, the tools must be optimized for administration in under ten minutes. The final deliverable consists of a validated set of screening tools fully integrated into the designated platform. This project is managed under the Community Residential Services Authority for the state of Illinois.

COMRESSERVAUTH586 - Community Residential Services Authority

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Notice of Correction to Award Information and Application and Submission Information for PA-27-037 "Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)"

Solicitation # NOT-OD-26-091

This notice provides corrections to the award and application information for the Predoctoral to Postdoctoral Transition Award (Parent F99/K00), specifically for solicitation NOT-OD-26-091 issued by the National Institutes of Health. The primary updates involve the removal of Kirschstein-NRSA support period limitations. Eligible individuals may now receive up to five years of aggregate support, consisting of up to two years at the F99 predoctoral level and up to three years at the K00 postdoctoral level. Additionally, the notice clarifies that a Certification Letter is no longer required for these applications, and corresponding instructions have been removed from the SF424(R&R) Other Project Information section. These changes are effective for the application due date of August 8, 2026. For further inquiries, the Division of Biomedical Research Workforce serves as the primary point of contact.

National Institutes Of Health Office Of The Director

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Notice of NIBIB Participation in PA-27-037: Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)

Solicitation # NOT-EB-26-005

The National Institute of Biomedical Imaging and Bioengineering is joining the Predoctoral to Postdoctoral Transition Award (Parent F99/K00), effective for applications received on or after December 08, 2026. This funding opportunity is designed for researchers transitioning from predoctoral to postdoctoral training, provided that clinical trials are not involved. All submitted applications must align with the specific missions of the participating Institutes and Centers. This update expands the list of participating organizations and agency contacts to include the National Institute of Biomedical Imaging and Bioengineering and its Chief Grants Management Officer. The award is supported by a wide array of National Institutes of Health offices and centers, including the National Cancer Institute and the National Institute on Aging, among others. All other terms and conditions of the original notice of funding opportunity remain unchanged.

National Institute Of Biomedical Imaging And Bioengineering

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Notice of FIC Participation in PA-26-002 "NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)"

Solicitation # NOT-TW-26-002

The Fogarty International Center is participating in the NIH Collaborative International Research Project, identified as PA-26-002. This funding opportunity is effective for applications submitted on or after January 25, 2027. The program is designed for collaborative international research projects and allows for optional clinical trials. A wide array of NIH Institutes and Centers are participating organizations, and applications must align with their specific missions. Additionally, the Office of Research on Women's Health, the INCLUDE Project, and the Office of Data Science Strategy may provide co-funding for assigned applications. All other terms and conditions of the original notice of funding opportunity remain unchanged.

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Thermal Performance & Dielectric Testing LaboratoryThis subcontract opportunity is for a Thermal Performance and Dielectric Testing Laboratory to provide independent testing and validation services for prime contractors supporting USAF AFLCMC/WAR F-22 cooling fluid projects. The selected provider will be responsible for evaluating low-temperature viscosity, high-temperature stability, and dielectric strength utilizing specialized equipment such as viscosity meters and stability chambers. The final deliverables for this engagement include comprehensive technical test reports and performance validation data. To be eligible, the contractor must be a domestic U.S. company and hold ISO/IEC 17025 accreditation. The work is associated with NAICS code 541715 and will be performed at Wright Patterson AFB. Interested parties must submit their responses by November 3, 2026.

FA8611 Aflcmc Wauk F22

POSTED

1 day ago

DEADLINE

in 14 days

AI Contract Overview

The U.S. Army Contracting Command Aberdeen Proving Ground Edgewood Division intends to award a sole source, firm fixed price contract to Aptagen LLC for the custom synthesis, purification, quality control, and delivery of DNA, RNA, and peptide aptamers. These materials are critical for diagnostic assay development, biosensor research, and chemical and biological defense platforms supporting the DEVCOM Chemical Biological Center. To meet strict technical requirements, the aptamers must undergo denaturing Polyacrylamide Gel Electrophoresis purification, as standard commercial HPLC or cartridge methods are deemed unacceptable. The vendor is required to provide double tier empirical quality control for every delivery using ElectroSpray Ionization Mass Spectrometry and 10 percent Urea Gel dPAGE analysis. This notice of intent is not a request for competitive quotations, but the government will review responses submitted to the designated contracting officials by September 1, 2026. The procurement falls under NAICS code 541715 and will be performed in Maryland.

General Info

Army sole source contract to Aptagen LLC for custom DNA, RNA, and peptides.

Agency

Department Of Defense → Department Of The Army

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

MD, 21010, USA

Set-Aside

NONE

Documents

No documents available

Documents will appear here when they are available.

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Timeline

PhaseClosed

PostedAug 25

special-notice

Response DeadlineSep 1

Deadline has passed

Submission Closed

09/01/2026, 04:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Defense → Department Of The Army

Contacts2 people available

OfficeN/A

Organization / AgencyDepartment Of Defense → Department Of The Army

Office AddressN/A

Contacts

Nicholas Granata Jr

contact@example.gov

Sammy Solo

contact@example.gov

Full Description

The U.S. Army Contracting Command – Aberdeen Proving Ground (ACC-APG), Edgewood Division intends to issue a Firm Fixed Price award on a sole source basis in accordance with Revolutionary Federal Acquisition Regulation Overhaul (RFO) FAR 6.103-1 to support the U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) and their requirement for a mission-critical, continuing requirement for the custom synthesis, purification, quality control, and delivery of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and peptide aptamers, with or without chemical modifications delivered in lyophilized form. These aptamers serve as foundational biological recognition elements in diagnostic assay development, biosensor research, and chemical/biological defense mission-support platforms.

The synthesized aptamers will undergo denaturing Polyacrylamide Gel Electrophoresis (dPAGE) purification. Standard commercial HPLC or cartridge purification is technically unacceptable.

The vendor will provide empirical sequence-verification data using both ElectroSpray Ionization (ESI) Mass Spectrometry and 10% Urea Gel dPAGE analysis with every delivery order (Double-Tier Empirical Quality Control).

The intent is to award this contract to Aptagen, LLC., CAGE Code 436H7. Aptagen LLC. is located at 250 North Main Street, Jacobus, PA 17407. At this time, it is the Government’s understanding that no other contractor is capable of supplying the required aptamers.

This notice of intent is not a request for competitive quotations; however, all responses received within seven (7) days of the issuance of this notice will be reviewed accordingly by the Government. Any response should be emailed to Contract Specialist, Sammy Solo at sammy.b.solo.civ@army.mil and Contracting Officer, Nicholas Granata Jr. at nicholas.granata.civ@army.mil by 12:00 pm EST on 01 September 2026.