This Government Contract opportunity from Department Of Defense was posted on September 24, 2021. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to Sole Source - Three (3) Joint Warfighter Medical Research Program Projects

Awarded

W81XWH21C0075Federal

Submission Closed09/21/2021, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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1 day ago

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AI Contract Overview

The Improving Neurotrauma by Depolarization Inhibition with Combination Therapy (INDICT) project is a Phase 2 randomized trial funded through the Congressionally Directed Medical Research Programs and the FY20 Joint Warfighter Medical Research Program. Managed by the Department of Defense and the USA Medical Research Acquisition Activity, the project is conducted as a sole-source award to the University of Cincinnati. The research is designed to determine the feasibility of implementing a neurocritical care treatment protocol guided by electrocorticographic monitoring of spreading depolarizations to treat patients with severe Traumatic Brain Injury. The primary objective of the study is to assess whether this specialized monitoring and guided management can reduce secondary brain insults more effectively than standard care. This goal will be pursued through a single clinical trial utilizing a uniform protocol across three study sites. The project is categorized under NAICS code 541715 and is intended to augment high-priority medical requirements for existing research projects that are nearing the achievement of their objectives.

General Info

Agency

Department Of Defense → W4PZ USA Medical Rsch Acquis Act

Contract Value

$4,427,503.02

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Cincinnati, OH, 45220, USA

Set-Aside

NONE

Awardee

CINCINNATI UNIV OF

Award Issued Date

09/21/2021, 12:00:00 AM UTC

Documents

FY20 Joint Warfighter Medical Research Program J&A (JA-21-01-00246)

justification-and-authorization

Low

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Timeline

PhaseAwarded

PostedSep 24

Award Notice

AwardedSep 21

Contract was awarded

Submission Closed

09/21/2021, 12:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Defense → W4PZ USA Medical Rsch Acquis Act

Contacts1 person available

OfficeFORT DETRICK, MD, 21702-5014, USA

Organization / AgencyDepartment Of Defense → W4PZ USA Medical Rsch Acquis Act

Office AddressFORT DETRICK, MD, 21702-5014, USA

Contacts

Matthew Teel

contact@example.gov

Full Description

REQUIRING ACTIVITY: Congressionally Directed Medical Research Programs (CDMRP) PROJECT TITLE: - Improving Neurotrauma by Depolarization Inhibition with Combination Therapy (INDICT): a Phase 2 Randomized Trial, in Support of the Congressionally Directed Medical Research Program (CDMRP) DESCRIPTION OF WORK: The primary goals of this study are: (1) to determine the feasibility of implementing an neurocritical care treatment protocol guided by electrocorticographic (ECoG) monitoring of spreading depolarizations (SDs) to treat Traumatic Brain Injury (TBI) patients, and (2) to assess the effects of such protocol vs. standard care to reduce secondary brain insults. The specific aims are: (1) determine the feasibility of real-time SD monitoring to guide intensive care management of severe TBI, and (2) determine the effect of SD-guided vs. standard care management to reduce secondary brain insults in severe TBI. The aims will be accomplished in a single clinical trial with uniform protocol conducted at three study sites.