This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on May 28, 2020. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to Sole Source to Marshfield Clinic Research Institute

Awarded

75D301-20-Q-71871Federal

Submission Closed06/02/2020, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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FA8750 Afrl Rik

POSTED

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DEADLINE

in almost 2 years

AI Contract Overview

The Centers for Disease Control and Prevention intends to award a sole source firm fixed price purchase order to the Marshfield Clinic Research Institute for a long-term follow-up study regarding the third dose of the Measles-Mumps-Rubella (MMR) vaccine. The primary objective is to examine HLA associations with immune response and safety among young adults to better understand why some individuals generate low antibody responses and remain susceptible to disease. This study utilizes a well-characterized cohort of participants who received their third MMR dose between 2009 and 2010, with blood samples for serology testing collected between June 1, 2019, and May 31, 2021. Under this agreement, the contractor will perform targeted sequencing of DNA samples from blood specimens to determine HLA alleles across classic genes in the class I and II genomic regions. The scope of work includes the genetic testing of existing samples, the processing of additional samples as ordered by the Contracting Officer, and the preparation of a final report of findings. The period of performance is from July 1, 2020, to May 31, 2022, with all work conducted at the contractor's facility in Marshfield, Wisconsin. This sole source procurement is justified because the contractor already possesses the necessary samples and long-term serologic data, and the CDC lacks the internal capability to perform the required genetic testing.

General Info

Agency

Department Of Health And Human Services → CDC National Center For Immunization And Respiratory Diseases

Contract Value

$190,980

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Marshfield, WI, 54449, USA

Set-Aside

NONE

Awardee

MARSHFIELD CLINIC, INC.

Award Issued Date

06/15/2020, 12:00:00 AM UTC

Documents

Justification for Sole Source Procurement under $250,000

3 pages · justification-and-authorization

Low

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

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Timeline

PhaseAwarded

PostedMay 28

Combined Synopsis

AwardedJun 15

Contract was awarded

Submission Closed

06/02/2020, 09:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → CDC National Center For Immunization And Respiratory Diseases

Contacts1 person available

OfficeAtlanta, GA, 30333, USA

Organization / AgencyDepartment Of Health And Human Services → CDC National Center For Immunization And Respiratory Diseases

Office AddressAtlanta, GA, 30333, USA

Contacts

Puli Hoxhaj

contact@example.gov

+1 (555) 000-0000

Full Description

The Centers for Disease Control and Prevention intends to award a sole source firm fixed price purchase order to Marshfield Clinic Research Institute for a MMR3 long-term follow up study to study the role of genetics in vaccine-response to measles, mumps, and rubella following the third dose of Measles-Mumps-Rubella (MMR) The objective of this study is to examine HLA associations with immune response (neutralizing antibody titer) to measles, mumps, and rubella and safety following receipt of a third dose of MMR vaccine among young adults. Depending on the enrollment, we may be able to assess these outcomes after the second dose. Information from this study can provide better understanding regarding those who do not respond or generate low antibody response to (repeat) vaccination and thus remain potentially susceptible to disease. The participants had originally received their third MMR dose in 2009-2010 between 18-24 years of age. This cohort is well characterized; subjects sera results are available from immediately prior to the third dose, as well as one month, one year, and 5 years following the administration of the third dose. Blood samples for serology testing at 9 years since the third dose are collected during June 1, 2019-May 31, 2021. CDC does not have the capability to do genetic testing on the samples. Tasks to be Performed: Task 1: The contractor shall perform targeted sequencing of DNA samples from blood specimens of participants who agreed to participate in the genetic evaluation study when they were enrolled in the MMR3 Long-Term Follow-Up Study at the 9 year follow up visit. Testing shall be performed at the contractor's facility. The panel shall cover classic genes in the class I (HLA-A, HLA-B, and HLA-C) and II (HLA-DRB1/3/4/5, HLA-DQA1, HLA-DQB1, HLA-DPA1, and HLA-DPB1) HLA genomic regions. The sequenced regions should be adequate to allow determination of the HLA alleles for that gene. Task 2: When ordered by the Contracting Officer, the contractor will process additional samples in accordance with the requirements set forth in Task 1. Task 3: The Contractor shall prepare a final report of findings on the results of the testing. Place of Performance: Contractor's Facility; No travel is anticipated. Period of Performance: July 1, 2020 - May 31, 2022 This contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 13.106-1(b) (SAP) and 10 U.S.C. 2304(c)(1). Interested persons may identify their interest and capability to respond to the requirement or submit proposals. This notice of intent is not a request for competitive quotations; however, all quotations/responses received within five (5) days of the issuance of this notice will be considered by the government. A determination by the government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to Contract Specialist at contact@example.gov by COB 06-02-2020.