PCR-Free Library Preparation

The contract titled PCR-Free Library Preparation is a small business set-aside subcontract issued by the USDA Agricultural Research Service, specifically under the Arkansas Food and Agriculture Mission Area, with a NAICS code of 541611 for scientific research and development services. The work requires the preparation of high-quality sequencing libraries from extracted DNA using PCR-free methodologies to ensure minimal amplification bias, with strict adherence to appropriate control protocols throughout the process. This effort is critical for generating accurate genomic data without the artifacts introduced by PCR amplification, making it suitable for sensitive downstream applications in research and analysis. The opportunity is open to small businesses only under the Total Small Business Set-Aside classification, and responses must be submitted by June 5, 2026, at 10:00 PM Eastern Time. The place of performance is designated as Mississippi State, Mississippi, with a ZIP code of 39762. Although no specific point of contact is listed, the solicitation is publicly accessible via the SAM.gov platform, and interested parties must comply with all federal contracting requirements for small business participation. The absence of a solicitation number suggests this may be an internally managed opportunity, but all standard procurement obligations and performance terms apply.