This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on June 30, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
PFAS Analysis in HOPE 1000 Study
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The National Institutes of Health, on behalf of the National Institute of Environmental Health Sciences, is seeking qualified vendors to perform targeted and untargeted analysis of per- and polyfluoroalkyl substances (PFAS) and related environmental exposures in 903 plasma samples as part of the HOPE 1000 Study. This procurement is issued as a Request for Quotation under FAR Part 12 as a commercial item acquisition, with no set-aside and full and open competition, and is not expected to exceed the simplified acquisition threshold. The work requires advanced liquid chromatography with high-resolution mass spectrometry (LC-HRMS) to quantify specific PFAS compounds such as PFBS and TFA through targeted analysis, and to estimate relative quantities of novel PFAS, exposomics, and metabolomics through untargeted analysis across at least four analytical configurations. The contractor must meet stringent detection limits of 0.01 to 0.05 ng/mL in human plasma, participate in a nationally recognized proficiency testing program, perform rigorous quality control and assurance checks, and transfer all raw and processed data, including scripts and tools, to NIEHS using open and fair data frameworks. The contractor will also be responsible for receiving, storing at -80°C, and returning the 903 plasma samples, and providing technical consulting support for scientific manuscripts and presentations. Proposals must include detailed labor categories with estimated hours, fully loaded fixed hourly rates, breakdowns and justifications for other direct costs, and a total price. All offerors must maintain an active SAM registration, provide their Unique Entity Identifier and Taxpayer Identification Number, and certify their business size. Mandatory representations and certifications, including FAR 52.204-24 and FAR 52.204-26 regarding covered telecommunications equipment, must be submitted with the offer. Technical proposals must demonstrate clear and convincing evidence of capability, while all invoices must be submitted electronically through the Department of Treasury’s Invoice Processing Platform, adhering to NIH-specific instructions and meeting strict formatting requirements including proper remittance information and matching vendor details to the contract. The period of performance is approximately nine months, with delivery to be performed at the NIEHS facility in Durham, NC, and responses are due by June 18, 2026, at 3:00 pm Eastern Daylight Time. Award is anticipated for June 29, 2026, and will be made to the offeror whose proposal is most advantageous
General Info
Place of Performance
MD, USASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
COMBINED SYNOPSIS / SOLICITATION
Title: PFAS Analysis in HOPE 1000 Study
***THIS IS AN UPDATED COMBINED SYNOPSIS / SOLICITATION. THE ORIGINAL SYNOPSIS / SOLICITATION PROVIDED UNDER NOTICE 75N94026Q00055 PUBLISHED ON MARCH 18, 2026, WAS ISSUED AS A NON-COMPETITIVE ACQUISITION. NO AWARD WAS MADE AS A RESULT OF THIS ORIGINAL NOTICE.
THIS UPDATED COMBINED SNYOPSIS / SOLICITATION IS BEING RE-ISSUED UNDER A NEW NOTICE ID AS A FULL AND OPEN OPPORTUNITY. ALL CAPABLE VENDORS ARE ENCOURAGED TO PROVIDE A QUOTE FOR THE SERVICES DESCRIBED IN THE STATEMENT OF WORK MADE AS AN ATTACHMENT TO THIS UPDATED POSTING UNDER NOTICE ID: 75N94026Q00056 ***
(i) This is an updated combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals/quotes are being requested and a written solicitation will not be issued.
(ii) The solicitation number is 75N94026Q00056 and the solicitation is issued as a request for quotation (RFQ).
This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 12—Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold.
THIS IS A NOTICE OF INTENT, COMBINED SYNOPSIS / SOLICITATION TO AWARD A CONTRACT OR PURCHASE ORDER FOR THE ATTACHED STATEMEND OF WORK.
The National Institutes of Health Office of Acquisition and Logistics Management (OALM), on behalf of the National Institute of Environmental Health Sciences (NIEHS) intends to negotiate and award a purchase order via full and open competition procedures. The anticipated award will be made on or around 6/29/2026.
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, dated 03/13/2026.
(iv) The associated NAICS code 541380 and the small business size standard is $19M. This requirement has no set-aside restrictions.
(v) Project requirements:
The Contractor shall provide NIEHS with the services provided in the updated Statement of Work attached as part of this announcement.
Period of Performance:
The period of performance will be determined at time of award and will be approximately nine (9) months.
(vi) Delivery Location:
National Institute of Environmental Health Sciences (NIEHS)
111 TW Alexander Drive
Durham, NC 27709
(vii) The provision at FAR clause 52.212-1, Instructions to Offerors – Commercial Products and Commercial Services, applies to this acquisition.
(viii) The provision at FAR clause 52.212-2, Evaluation – Commercial Products and Commercial Services, applies to this acquisition.
- The award resulting from this solicitation will be made to the responsible offeror whose proposal is most advantageous to the Government, Technical Capability, Past Performance and other factors considered.
(b) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.
(ix) Offerors are to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services, with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer.
(x) The FAR clause at 52.212-4, Contract Terms and Conditions – Commercial Products and Commercial Services, applies to this acquisition.
The following FAR provisions or clauses are incorporated by reference:
52.204-7, System for Award Management (Nov 2024)
52.204-13, System for Award Management Maintenance (Oct 2018)
52.204-16, Commercial and Entity Code Reporting (Aug 2020)
52.204-18, Commercial and Entity Code Maintenance (Aug 2020)
HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015).
52.212-4(g), Invoice, is supplemented by the NIH Invoice and Payment Instructions (3/2023).
(xi) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders–Commercial Products and Commercial Services (Oct 2025), applies to this acquisition
(xii) The offeror must complete and return FAR 52.204-24 and FAR 52.204-26 with its offer.
(xiii) Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.
In addition the Unique Entity Identifier (UEI), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.
All responses must be received by June 18, 2026, 3:00 pm, Eastern Daylight Time and reference number 75N94026Q00056. Responses shall be submitted electronically to Gannon White, Contracting Officer, contact@example.gov, and Alice Pagán Pereira, Contracting Officer, contact@example.gov.
(xiv) The name of the individual to contact for information regarding the solicitation:
Gannon White, Contracting Officer, contact@example.gov.
Attachments:
- FAR 52.204-24
- FAR 52.204-26
- Invoice and payment provisions
- Statement of Work (UPDATED): SOW for HOPE 1000 PFAS Analysis 6.11.26
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