PowerFuge Pilot: A stainless-steel system for high-speed bioseparation

The PowerFuge Pilot project outlines the development and deployment of a stainless-steel, high-speed decanting centrifuge system designed for pilot-scale microbial biomanufacturing applications, specifically for the primary separation of microbial cells from culture fluid. This liquid-solid separation technology is critical in biopharmaceutical processing to ensure efficient purification of biological products at an early development stage, supporting scalability and regulatory compliance in manufacturing workflows. The system is intended to meet the precision and hygiene standards required by the Food and Drug Administration for biological product production environments. The initiative is forecasted by the FDA under NAICS code 333249, indicating classification within other commercial and service industry machinery manufacturing. The point of contact for program inquiries is the Cder Acquisition Liaison, with an email provided for correspondence, while the contracting officer role remains unnamed as of the posting date of May 25, 2026. The opportunity is posted on the HHS OSDBU platform and does not specify a place of performance or set-aside status, suggesting it is open to qualified vendors nationwide with no geographic or socioeconomic restrictions indicated. The project signifies the FDA’s investment in advanced bioseparation capabilities to enhance the efficiency and reliability of next-generation biomanufacturing processes.