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Purification Process Scale-Up Engineering

Active

Federal

Response Deadline11/09/2026, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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This subcontract for the Defense Advanced Research Projects Agency involves providing scale-up engineering services to transition small-scale biochemical processes into high-throughput platforms. The primary objective is to deliver a scaled-up purification platform by optimizing yield and flow rates through the use of fluid dynamics modeling software and industrial-scale chromatography columns. All protein production activities must strictly adhere to Good Manufacturing Practice standards. This effort supports prime contractors on DARPA projects to ensure the successful transition of biochemical processes to an industrial scale.

General Info

DARPA subcontract for scale-up engineering services to create high-throughput biochemical purification platforms.

Agency

Department Of Defense → Defense Advanced Research Projects Agcy

NAICS

541330 - Engineering Services

Place of Performance

VA

Set-Aside

NONE

Documents

This scope was carved out of DARPA-SN-27-01.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Protein Palace Proposers Day

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Timeline

PostedOct 22

subcontract

Response DeadlineNov 9

Submission deadline

Response Deadline

11/09/2026, 12:00:00 PM UTCin 17 days

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy

Office AddressN/A

ContactsNo contact information available

Full Description

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Performs scale-up engineering for prime contractors on DARPA biochemical projects to transition small-scale processes to high-throughput platforms. Optimizes flow rates and yield using industrial-scale chromatography columns and fluid dynamics modeling software. Adheres to GMP standards for protein production. Delivers a scaled-up purification platform capable of high-throughput production.

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