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Tunable Protein Purification System R&D

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Tunable Protein Purification System R&D is a subcontract under the Defense Advanced Research Projects Agency within the Department of Defense. The project focuses on core research and engineering to design and build a tunable purification platform intended for prime contractors on DARPA biochemical projects. The primary objective is to develop mechanisms that target proteins based on physicochemical heterogeneities, shifting away from traditional affinity methods through the use of novel membranes, microfluidics, or advanced chromatography. The successful contractor must adhere to DARPA IV&V protocols to ensure rigorous validation and verification. Final deliverables include a fully functional, tunable purification platform along with comprehensive process documentation. This effort is categorized under NAICS code 541715, with a response deadline set for November 9, 2026.

General Info

DARPA subcontract to develop a tunable protein purification platform by November 9, 2026.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

VA

Set-Aside

NONE

Documents

This scope was carved out of DARPA-SN-27-01.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Protein Palace Proposers Day

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
ContactsNo contacts available
OfficeN/A
Office AddressN/A
ContactsNo contact information available

Full Description

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Performs core research and engineering to design and build a tunable purification platform for prime contractors on DARPA biochemical projects. Develops mechanisms to target proteins based on physicochemical heterogeneities, moving beyond affinity methods. Utilizes advanced chromatography, microfluidics, or novel membranes. Adheres to DARPA IV&V protocols. Delivers a functional, tunable purification platform and process documentation.

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