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R -- The Induction and Isolation of microsomal enzymes.

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3ATSDR2852Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The CDC plans to award a sole source purchase order to the University of Georgia to conduct a project focused on inducing and isolating microsomal enzymes in adult female and immature rodents after exposure to volatile organic compounds (VOCs). The objective is to use the resulting in vivo data to validate computer-based physiologically based pharmacokinetic (PBPK) modeling parameters such as Km and Vmax for different substrates across age groups ranging from birth through sexual maturation. This procurement is justified under FAR part 6.302-1 as the University of Georgia is identified as the only entity with the necessary expertise to carry out this specialized work. No competitive solicitation is being issued, but the CDC invites other firms that believe they can perform the required services to notify the Contracting Officer in writing within 15 days of the synopsis publication. The government will use any responses received solely to decide whether to proceed with a competitive process, and the final decision rests entirely with the government. Questions or inquiries about the project can be directed to Christine Dorsey via email or fax as provided.

General Info

CDC awards sole source contract to University of Georgia for rodent enzyme research validating PBPK models.

Agency

N/A

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

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Timeline

Posted

special-notice

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Organization & Contact Information

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AgencyN/A
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ContactsNo contact information available

Full Description

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The Centers for Disease Control and Prevention (CDC) intends to award, on a sole source basis, a purchase order to University of Georgia located in Athens, GA. The purchase order is for the purpose of performing a project to induce and isolate microsomal enzymes in adult female and immature rodents following exposure to VOCs. This project is to use this in vivo data to validate data generated ( e.g. Km and Vmax) in a computer based physiologically based pharmacokinetic modeling system for each substrate for closely-spaced age groups, from birth until sexual maturation. The authority for this sole source procurement is FAR part 6.302-1 in that University of Georgia is the only known source with the knowledge required to provide this project. This is not a request for competitive proposals and no solicitation is available. Firms that believe they can provide the required services are encouraged to identify themselves and give written notification to the Contracting Officer within 15 days from the publication date of this synopsis. A determination by the Government not to compete this proposed action based on responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Inquiries may be sent to Christine Dorsey by e-mail at contact@example.gov or by fax at +1 (555) 000-0000.

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