This Solicitation opportunity from Department Of Defense was posted on July 2, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) - TA3

Closed

DARPA-PA-26-09Federal

Submission Closed07/29/2026, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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Federal

Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response

Solicitation # 75A50126R00001_RFP_NPIVS_27

The Biomedical Advanced Research and Development Authority (BARDA) is soliciting proposals for the Vaccine Medical Countermeasures (MCMs) for Pandemic Influenza Preparedness and Response Program. The primary objective is to maintain a permanent readiness posture and a commercially sustainable warm-base production capacity for the rapid manufacture of vaccines, antigens, and adjuvants during public health emergencies. Contractors are required to produce these countermeasures against influenza and other viruses with pandemic potential, generate and submit all necessary analytical, nonclinical, clinical, and chemistry, manufacturing, and controls data to the FDA, and support rapid regulatory decisions. To be eligible, offerors must hold a U.S. influenza vaccine license or have developed an influenza vaccine as evidenced by a Biologics License Application submission. The contract is structured as an IDIQ with a five-year base period and a potential five-year option period, totaling a possible 120-month ordering period. Award decisions will be based on the Highest Technically Rated Offerors with a Fair and Reasonable Price methodology, with a significant emphasis on capabilities. Key requirements include strict adherence to CGMP guidelines, the implementation of comprehensive business and supply continuity plans, and the submission of surge manufacturing and supply chain readiness assessments. Deliverables include the preparation of candidate vaccine viruses and the management of complex logistics, including temperature-controlled shipping and specific packaging standards. Payment is processed quarterly via the Department of Treasury Invoice Processing Platform.

Barda - Aspr / Daappo / Barda Dcma

POSTED

DEADLINE

Industry Day: DARPA Documentation & Decision Support Sprint (D2)

Solicitation # DARPA-SN-26-118

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Defense Advanced Research Projects Agcy

POSTED

DEADLINE

DARPA Surgical Competition (DSC) Industry Day

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Defense Advanced Research Projects Agcy

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FDA Office Of Acq Grant Svcs

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Solicitation # 80JSC026Q0008

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NASA Johnson Space Center

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DEADLINE

Hypobaric Chamber Pilot Studies

Solicitation # 80JSC026Q0006

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NASA Johnson Space Center

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Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation CenterThe National Institutes of Health, through the NINDS, is forecasting the establishment of a Diagnostic Research Innovation Center to support the next phase of the Undiagnosed Diseases Network. This center will operate as part of a broader ecosystem including the Clinical and Data Coordinating Center, Networks of Diagnostic Excellence, and the NIH Undiagnosed Diseases Program. The primary objective of the center is to advance innovative diagnostic tools and strategies for both genomic and non-genomic conditions, which includes the systematic re-evaluation of unsolved cases from previous network phases. The center will focus on generating and testing diagnostic hypotheses by utilizing advanced sequencing, multi-omics, and gene function studies in animal and human in vitro models. By collaborating with various network stakeholders, the center aims to identify novel disease-associated genes, genomic variants, and new syndromes. This initiative seeks an integrated center featuring investigators with a history of scientific synergy and collaboration. While this is currently a forecast to allow potential applicants time to plan and establish partnerships, formal applications are not yet being solicited.

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study entitled “Malaria and vector borne disease surveillance in the Colombia/Venezuela border”

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National Institutes Of Health Olao

POSTED

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TIDAL: Target-Induced Droplet Assembly of Ligands

Solicitation # S-197478

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Triad - DOE Contractor

POSTED

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Master Protocol Development & Adaptive Design

POSTED

DEADLINE

Phase I/II Clinical Trial Management & Execution

W6QK Acc-Apg

POSTED

8 days ago

DEADLINE

in 5 days

AI Contract Overview

The RAPIID program, specifically Task Area 3, aims to bridge the gap between lab-scale breakthroughs in shelf-stable blood analogs and real-world deployment by advancing the regulatory approval, manufacturing scalability, and field usability of components originally developed under the FSHARP program. These components, designed to replicate the critical functions of whole blood—oxygen delivery, hemostasis, and volume expansion—now require rigorous clinical validation to demonstrate safety and efficacy when used in combination, as well as scalable production processes to ensure consistent, high-volume output. Efforts under this solicitation will focus on pushing these technologies through the regulatory pathway to secure necessary approvals for military and civilian use in austere, pre-hospital environments. The initiative seeks to develop and scale enabling fielding technologies that support the deployment, storage, and administration of these blood analogs outside controlled laboratory settings. This includes not only the components themselves but also the logistical and operational frameworks needed to integrate them into frontline medical workflows. Proposals must address the full spectrum of challenges—from manufacturing robustness and regulatory compliance to usability in extreme conditions—while aligning with the program’s goal of delivering a complete, authorized system capable of saving lives where traditional blood supplies are unavailable. The solicitation, issued by DARPA’s Biological Technologies Office, has a response deadline of July 29, 2026, and is open to all qualified entities, targeting the NAICS code 541714 for research and development in physical, engineering, and life sciences.

General Info

Advance shelf-stable blood analogs for military use through regulatory approval, scalable manufacturing, and field deployment.

Agency

Department Of Defense → Defense Advanced Research Projects AgcyView Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Set-Aside

NONE

Documents

(8)

RAPIID Controlled Unclassified Information Guide v1

PDF•other

DARPA-PA-26-09 Resuscitation and Prevention of Ischemia-Induced Dysfunction (RAPIID) Task Area-3 Program Announcement

PDF•program-announcement

DARPA-PA-26-09 RAPIID TA-3 Task Description Document

DOCX•task-description-document

RAPIID TA-3 Schedule of Milestones and Payments

XLSX•schedule-of-milestones-and-payments

DARPA-PA-26-09 RAPIID TA-3 Technical and Management Proposal Template

DOCX•rfp

DARPA Model Other Transaction Agreement for Research

DOCX•contract-document

DARPA-PA-26-09 RAPIID TA-3 Cost Proposal Attachment B

DOCX•cost-proposal

DARPA Standard Cost Proposal Spreadsheet November 2021

XLSX•cost-proposal-spreadsheet

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedJul 2

Solicitation

Response DeadlineJul 29

Deadline has passed

Submission Closed

07/29/2026, 12:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy

Contacts1 person available

OfficeARLINGTON, VA, 222032114, USA

Organization / Agency

Department Of Defense → Defense Advanced Research Projects Agcy

View Agency Profile

Office AddressARLINGTON, VA, 222032114, USA

Contacts

LCDR Robert Murray Program Manager DARPA/BTO

contact@example.gov

Full Description

Please note that this announcement specifically solicits proposals only for Task Area 3 (TA-3) of the RAPIID program.

Primary challenges with translating technological advancements from the laboratory to real-world usage include a lack of investment to ensure manufacturing scalability, and usability, as well as clinical, regulatory, and commercialization preparedness. Previous investments by DARPA to address potential blood shortages in austere, pre-hospital settings (i.e., the Fieldable Solutions for Hemorrhage with bio-Artificial Resuscitation Products (FSHARP) program) have derisked scalable, shelf-stable components that would provide the resuscitative functions of whole blood (i.e., oxygen delivery, hemostasis, and volume expansion) when used together. However, bringing those components through clinical studies and regulatory approval as well as the development of enabling technologies and guidance to facilitate their use outside of the laboratory were out-of-scope in previous DARPA efforts. RAPIID is designed to bridge the gap between the proof-of-concept achievements of the FSHARP program and actual clinical use by the military and civilians. With FSHARP demonstrating that shelf-stable blood products can be created, DARPA is now taking on the next challenge: delivering a complete, deployable, and authorized system that can save lives in the field. To achieve this goal, RAPIID will focus on pushing high technology readiness level (TRL)/medical readiness level (MRL) capabilities through the regulatory process by funding studies to demonstrate safety and efficacy of blood analog components and their ability to work in combination; manufacturing scalability of individual blood analog components; and developing and scaling associated fielding technologies.