NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional)
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The National Institutes of Health, through the National Institute of Diabetes and Digestive and Kidney Diseases, is inviting applications for Disease Research and Translational Core Centers under the P30 mechanism, which is clinical trial optional. These centers aim to strengthen existing research institutions with established programs in cystic fibrosis, diabetes, nutrition, obesity, liver, and digestive diseases by fostering multidisciplinary collaboration, improving research rigor and reproducibility, and enhancing cost efficiency. The centers are structured around shared core services that provide access to specialized equipment, technical resources, analytical support, and expert-led training, all tailored to the specific needs of the research community within the institution. They also include a Pilot and Feasibility Grant Program to support new projects and a Scientific Catalyst Program administered through the Administrative Core, which promotes team building, mentoring, workshops, seminars, and visits by expert scientists to stimulate innovation and attract new investigators to the field. The program places strong emphasis on creating a nurturing environment for trainees and early-stage investigators, ensuring that emerging researchers benefit from mentorship and integrated scientific networks. Core services must be operated or overseen by recognized experts and are designed to be shared across center members to maximize impact and efficiency. The Scientific Catalyst Program specifically supports activities that build research capacity, encourage cross-disciplinary partnerships, and align scientific efforts with the center’s focus on chronic diseases. Applications are expected to demonstrate how the proposed infrastructure will enhance existing strengths and expand the institute’s research trajectory. The funding opportunity was posted on July 2, 2026, and inquiries should be directed to the designated NIDDK contact for further details.
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This Notice of Funding Opportunity (NOFO) invites applications for NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional). These Core Centers are part of an integrated program of biomedical and translational research supporting our cystic fibrosis, diabetes, nutrition, obesity, liver and digestive diseases research. They enhance multidisciplinary collaboration, rigor, reproducibility, replication and research cost efficiencies at institutions that already have a large established research base in one of the above focused areas within NIDDK’s mission. They should also provide a rich mentoring environment for trainees and early-stage investigators. The P30 Centers accomplish their purpose by providing a Pilot and Feasibility Grant Program, a Scientific Catalyst Program, and importantly shared access to the services of Cores. Within a given P30 Center, the Scientific Catalyst Program, which works within the Administrative Core, supports activities that strengthen the Center’s scientific community and advance its research mission. Activities may include research team building, investigator mentoring, seminars, workshops, visiting scientists, and scientific research series. The program is intended to foster multidisciplinary collaboration, attract new investigators, and engage investigators with expertise relevant to the Center’s chronic disease research focus. The Core Services reflect the research needs of the Center and may include research consultation along with services involving cell or other models, planning, analysis, hands-on services, access to expensive specialized equipment, other technical resources or training shared by the Center members and operated or overseen by recognized experts.
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