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Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

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Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute on Aging is issuing a forecast for the Alzheimer's Drug-Development Program to support the pre-clinical and early-stage clinical Phase I development of novel biologic and small-molecule drug candidates. The program aims to identify treatments that prevent Alzheimer's disease, slow its progression, or address cognitive and behavioral symptoms. Funding is available for academic and biotech researchers to conduct development activities internally or through specialized contract research organizations. The initiative focuses on expanding the portfolio of investigational drug candidates for emerging therapeutic targets and diversifying the therapeutic pipeline to support mono-therapy, combination therapy, and precision medicine approaches. This opportunity will utilize the U01 activity code. While applications are not currently being accepted, this notice serves to allow potential applicants time to establish collaborations and design responsive projects.

General Info

NIA forecast for Alzheimer's drug development funding for pre-clinical and Phase I research.

Agency

Department Of Health And Human Services → National Institutes Of HealthView Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
View Agency Profile
Office AddressUSA
Contacts
NIA Scientific Program Contact
contact@example.gov

Full Description

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The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose pre-clinical and early-stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that aim to prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms.

Through the NOFO, NIA is continuing the Alzheimer's Drug-Development Program (ADDP) with the aim of catalyzing drug development for AD. The ADDP is designed to provide funding support to academic and biotech researchers for preclinical drug development activities that can be conducted in their own laboratories or conducted in collaboration with contract research organizations that specialize in preclinical drug development activities. By supporting the most challenging and costly steps of drug development and seamlessly connecting preclinical drug development and first-in-human testing for drug candidates, the ADDP program seeks to: 

  • Continue to expand the number of investigational new drug candidates for a portfolio of emerging therapeutic targets; 
  • Continue to expand the therapeutic pipeline for AD with drug candidates targeting multiple underlying disease mechanisms that can be used as mono-therapy or as part of combination therapy; and
  •  Enable a precision medicine approach to AD drug development. 

The NOFO will utilize the U01 activity code. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

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