Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, August 19 at 2:00 PM EDT

Register Free →
logo
Get CLEATUS

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Institutes of Health, through the National Institute of Neurological Disorders and Stroke and the National Heart, Lung and Blood Institute, is seeking to support the infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). This initiative focuses on establishing clinical enrollment hubs to conduct trials aimed at improving outcomes for individuals experiencing non-stroke neurological and cardiovascular emergencies within pre-hospital or emergency department settings. This notice serves as a forecast to allow potential applicants time to establish collaborations and develop responsive applications. While the program aims to identify effective early-stage treatments, applications are not currently being solicited. Interested parties can contact the NINDS Department of Emergency Medicine for further information.

General Info

NIH forecast for SIREN network hubs conducting non-stroke neurological and cardiovascular emergency trials.

Agency

Department Of Health And Human Services → National Institutes Of HealthView Agency

NAICS

621910 - Ambulance ServicesView NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

forecast

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
View Agency Profile
Office AddressUSA
Contacts
NINDS Department of Emergency Medicine
contact@example.gov

Full Description

Show more

The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care. 

Applications are not being solicited at this time.  This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers. 

Similar Contracts

Same NAICS industry code

NAICS: 621910
New
SLED
Two(2) Type 1 Ambulances
Solicitation # PE-77523-NONST-2026-000000081
The Bryan County Board of Commissioners is seeking qualified firms to provide two custom-built Type 1 ambulances for the Bryan County Fire and Rescue Department. Interested vendors must submit sealed bid proposals by 2:30 PM EST on September 10, 2026. All inquiries regarding the request for proposals must be emailed to Finance Director Charlene Bunch by 5:00 PM EST on August 20, 2026. The selection process will be based on the Board of Commissioners' judgment of the most qualified firm that meets the specific requirements of the commission. Bryan County maintains the right to reject any or all proposals, waive minor irregularities, or advertise for new bids. This solicitation does not constitute a commitment to execute a contract or reimburse costs associated with proposal preparation.
Bryan County Board of Commissioners

POSTED

about 4 hours ago

DEADLINE

in 28 days
View Details
NAICS: 621910
New
Federal
V225--Ground Ambulance Service
Solicitation # 36C24526Q0727
Solicitation 36C24526Q0727 is a firm-fixed-price, five-year single award Indefinite Delivery Indefinite Quantity (IDIQ) contract issued by the Department of Veterans Affairs Network Contracting Office 5. The contract provides ground ambulance services for the Washington DC VA Medical Center and its associated Community-Based Outpatient Clinics, including the Charlotte Hall VA Clinic in Maryland. Services are provided on an as-needed basis and encompass Basic Life Support, Advanced Life Support, Critical Care Transport Tiers 1, 2, and 3, and urgent non-emergent stretcher transports. The contract ceiling is set at 8,900,000 dollars, with a minimum guaranteed amount of 1,000 dollars. The ordering period extends from the date of award through September 30, 2031, with final deliveries not required after September 30, 2032. The contractor is responsible for transporting patient luggage, medical records, and medication at no additional cost, and must return VA staff and equipment to the original pickup location. Personnel must meet all federal, state, and local qualifications, and the contractor must provide a policy on tuberculosis exposure and decontamination. Performance is monitored through a Quality Control Plan and a Government-prepared Quality Assurance Surveillance Plan, with specific metrics requiring scheduled pickups to be within 30 minutes of the scheduled time and incident reports to be submitted within one hour by telephone. Invoicing is conducted monthly in arrears via the FSC e-Invoice Payment portal, with claims submitted through the VetRide Vendor Portal or approved transportation software. This unrestricted acquisition incorporates various FAR and VAAR clauses, including specific requirements for service contract labor standards and the provision of uniforms and paid leave for employees.
245-NETWORK Contract Office 5 (36C245)

POSTED

1 day ago

DEADLINE

in 5 days
View Details
NAICS: 621910
New
SLED
Ambulance Unit/Medical Services - Term Contract
Solicitation # 50001-2893
LSU Baton Rouge is seeking a term contract for ambulance units and medical services under solicitation number 50001-2893. This opportunity is issued by the state of Louisiana and is open for responses until August 25, 2026, at 5:00 PM. The contract will be performed within the state of Louisiana. Interested parties should direct all inquiries to the Office of Procurement Services via email at purchase@lsu.edu or by phone at 225-578-2176.
LSU - Baton Rouge

POSTED

2 days ago

DEADLINE

in 12 days
View Details
NAICS: 621910
New
Federal
Bariatric Patient Transport Services
255-NETWORK Contract Office 15 (36C255)

POSTED

2 days ago

DEADLINE

N/A
View Details
NAICS: 621910
New
Federal
Critical Care Transport (CCT) Services
255-NETWORK Contract Office 15 (36C255)

POSTED

2 days ago

DEADLINE

N/A
View Details
NAICS: 621910
New
Federal
Basic Life Support (BLS) Non-Emergency Medical Transport
255-NETWORK Contract Office 15 (36C255)

POSTED

2 days ago

DEADLINE

N/A
View Details
NAICS: 621910
New
Federal
Advanced Life Support (ALS) Emergency Ambulance Transport
255-NETWORK Contract Office 15 (36C255)

POSTED

2 days ago

DEADLINE

N/A
View Details
NAICS: 621910
New
Federal
FMC Devens Ambulance ServicesThe contract pertains to providing ambulance services specifically for the adult in-custody population at FMC Devens, located in Worcester, Massachusetts. It is a forecasted opportunity issued by the Federal Prison System under the Department of Justice and is designated as a Small Business Total Set-aside, aiming to promote participation by small businesses. The associated NAICS code for this contract is 621910, indicating it falls under ambulance services. Key points of contact for this contract include Sarah Burke and the designated Small Business Specialist within the Bureau of Prisons’ administration. While specific solicitation details such as number and posted dates are available, the exact terms and scope will likely be detailed upon solicitation release. The opportunity emphasizes contracting within the small business community to support critical medical transport services for incarcerated adults at FMC Devens.
Federal Prison System / Bureau Of Prisons

POSTED

3 days ago

DEADLINE

N/A
View Details
NAICS: 621910
New
SLED
On-Site Emergency Medical Response Services
CITY OF SAN ANTONIO

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 621910
New
SLED
Emergency Medical Services at the Alamodome
Solicitation # RFP 26-095; RFx 6100019742
The City of San Antonio is soliciting proposals from licensed Emergency Medical Services providers to deliver comprehensive emergency medical care and related services at events held at the Alamodome. The selected contractor will be responsible for supplying all necessary personnel, supervision, medical supplies, equipment, and resources required to ensure timely and effective emergency response during events. Services must be rendered in strict compliance with the requirements outlined in the solicitation, ensuring the safety and well-being of attendees, staff, and participants at all times. The solicitation, identified by number 6100019742, was posted on August 10, 2026, with responses due by September 24, 2026, at 5:00 PM. This procurement is issued by the City of San Antonio under the State and Local Government category, with no specific set-aside designation. All services are to be performed at the Alamodome in San Antonio, Texas, and the primary point of contact for inquiries is Gregory Desir, with additional support available from Troy Elliott and Angelica Mata in the Finance Procurement office. Interested parties may access the full solicitation details through the Texas SmartBuy portal.
CITY OF SAN ANTONIO

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 621910
New
Federal
Aero-Medical Air Ambulance Operations (Levels I–III)
Commanding General

POSTED

3 days ago

DEADLINE

in 18 days
View Details
NAICS: 621910
New
Federal
MCAGCC/MAGTFTC Air Ambulance MEDEVAC Services
Solicitation # M0068127RAIRAMBULANCE
The U.S. Marine Corps is seeking market information for a contract to provide continuous 24/7/365 air ambulance and non-medical air transportation services to support the Marine Air Ground Task Force Training Command and Marine Corps Air Ground Combat Center in Twentynine Palms, California. The requirement calls for a rotary-wing aircraft equipped with a certified flight crew and dedicated medical personnel capable of conducting immediate medical evacuations and routine non-medical flights across all training areas, ranges, and Camp Wilson. All operations must comply with FAA and Air Mobility Command Commercial Airlift Review Board regulations and adhere to strict aircraft safety protocols. The service provider must maintain readiness to launch emergency missions within a 30-minute window, with mission frequency driven by training intensity and medical needs. The contract encompasses both Medical Evacuation services and Category IV non-medical air transportation, requiring consistent operational presence and rapid response capability throughout the year. The solicitation is classified as a sources sought notice under NAICS code 621910, with no set-aside currently planned. Interested parties must submit responses by August 31, 2026, and inquiries should be directed to Corey Slivnik or Maria Caceres at the designated email addresses. The contract will be managed from Camp Pendleton, California, with all performance centered at the Twentynine Palms installation.
Commanding General

POSTED

3 days ago

DEADLINE

in 18 days
View Details

More opportunities from Department Of Health And Human Services → National Institutes Of Health

Same awarding agency

NAICS: 541714
New
Grant
Established Clinician Investigator Award to Support Mentoring (KS1)The Established Clinician Investigator Award to Support Mentoring (KS1) is a forecast opportunity issued by the National Institutes of Health under the Department of Health and Human Services. This award is designed to provide established clinician investigators with a sustained period of protected time, enabling them to deliver high-quality mentoring and guidance to early-career clinician research scientists. The program is managed by the Division of Biomedical Research Workforce, which serves as the primary point of contact for interested parties. While specific performance locations and set-aside details are not listed, the award aims to strengthen the pipeline of clinician researchers through structured mentorship support.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 541715
New
Grant
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)The National Institutes of Health, through the National Institute of Neurological Disorders and Stroke and the National Heart, Lung and Blood Institute, is seeking to provide continued support for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). This initiative focuses on conducting clinical trials to improve outcomes for patients experiencing non-stroke neurological and cardiovascular emergencies within pre-hospital or emergency department settings by identifying effective early-stage treatments. The program specifically seeks to establish a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC) to support the network's infrastructure. While this notice serves as a forecast to allow potential applicants time to form collaborations and prepare responsive applications, formal solicitations are not currently being accepted.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 611430
New
Grant
Mentored Career Transition Award (KT1/R00)The Mentored Career Transition Award (KT1/R00), issued by the National Institutes of Health under the Department of Health and Human Services, is a biphasic grant designed to transition postdoctoral researchers into independent, tenure-track faculty roles. The award provides up to five years of total support, beginning with a mentored career development phase lasting one to two years. The second phase offers up to three years of independent research funding, which is contingent upon the recipient's satisfactory progress during the initial phase and the procurement of an approved, research-intensive faculty position. This forecasted opportunity is managed by the Division of Biomedical Research Workforce.
Professional and Management Development Training

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 541714
New
Grant
Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)The National Institute on Aging is issuing a forecast for the Alzheimer's Drug-Development Program to support the pre-clinical and early-stage clinical Phase I development of novel biologic and small-molecule drug candidates. The program aims to identify treatments that prevent Alzheimer's disease, slow its progression, or address cognitive and behavioral symptoms. Funding is available for academic and biotech researchers to conduct development activities internally or through specialized contract research organizations. The initiative focuses on expanding the portfolio of investigational drug candidates for emerging therapeutic targets and diversifying the therapeutic pipeline to support mono-therapy, combination therapy, and precision medicine approaches. This opportunity will utilize the U01 activity code. While applications are not currently being accepted, this notice serves to allow potential applicants time to establish collaborations and design responsive projects.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 541715
New
Grant
Mentored Research Scientist Career Development Award (KR1)The Mentored Research Scientist Career Development Award (KR1), issued by the National Institutes of Health under the Department of Health and Human Services, is designed to support candidates with research doctoral degrees in their pursuit of future research independence. The award provides up to five years of protected time for intensive career development under the guidance of an experienced mentor. This opportunity is currently listed as a forecast with a posted date of August 13, 2026. Interested parties can contact the Division of Biomedical Research Workforce via email at nihtrain@mail.nih.gov for further information.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 541715
New
Grant
Mentored Clinician Research Scientist Career Development Award (KC1)The Mentored Clinician Research Scientist Career Development Award (KC1) is a forecast opportunity provided by the National Institutes of Health under the Department of Health and Human Services. This award is designed to support clinician research scientists with clinical doctoral degrees, offering up to five years of protected time to undergo intensive research career development. The primary goal of the program is to prepare these candidates for future research independence through the guidance of an experienced mentor. Interested parties can contact the Division of Biomedical Research Workforce for further information. The award is listed as a forecast with a posted date of August 13, 2026, and detailed information can be accessed through the grants.gov portal.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 17 hours ago

DEADLINE

N/A
View Details
NAICS: 518210
Grant
Partnership with Common Fund Data Ecosystem ResourcesThe NIH Office of Strategic Coordination through its Common Fund is seeking partnerships between Common Fund data programs and external biomedical data resources to improve the reusability and integration of Common Fund datasets within broader scientific ecosystems. The initiative aims to advance the FAIR principles—Findable, Accessible, Interoperable, and Reusable—by fostering collaborations that bridge the Common Fund Data Ecosystem with other significant NIH data platforms such as the HEAL Data Ecosystem, BRAIN Initiative, Cancer Research Data Commons, ImmPort, TOPMed, and the Medical Imaging and Data Resource Center. These partnerships are intended to develop shared resources that enhance data connectivity, enable cross-platform analysis, and promote broader scientific utility of Common Fund data without supporting new clinical trials. The funding opportunity is open to non-CF biomedical data resources that can contribute infrastructure, tools, or expertise to amplify the impact of Common Fund datasets. Applicants must propose concrete plans for integration, interoperability, and sustainability of jointly developed resources. While no specific funding amount or deadline is indicated in the provided data, the solicitation was posted on August 6, 2026, and inquiries may be directed to the Common Fund Data Ecosystem Program via cfde@od.nih.gov. This effort reflects a strategic push by the NIH to unify diverse biomedical data ecosystems under common standards, enabling more comprehensive and efficient data-driven research across disciplines and institutions.
Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services

POSTED

8 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Transformative Technologies for Experimental and Computational RNome Characterization and Functional AnalysisThe NIH Common Fund, in collaboration with other NIH Institutes and Centers, is preparing to issue a funding opportunity for the Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis initiative under the RNomics program. This initiative aims to develop high-risk, early-stage experimental and computational technologies that overcome major limitations in current RNA analysis methods, with a focus on sequencing RNA, detecting modifications, studying RNA function, and analyzing RNA across molecules, cells, and tissues. The program seeks innovations that have not yet been demonstrated at scale or in biologically relevant systems, prioritizing groundbreaking tools that can advance understanding of health and disease through integrated analysis of the entire RNome. This is a two-phase effort, where successful Phase 1 projects will be evaluated for transition to Phase 2, which is designed to deliver validated, widely usable tools for the scientific community. Applications are not currently being accepted; this notice serves as a forecast to allow potential applicants time to form collaborations and refine proposals. The initiative is part of a broader RNomics effort that includes technology enhancement centers, molecular standards, and a coordinating center, all aimed at establishing comprehensive RNA research capabilities. The funding opportunity will be administered by the National Institutes of Health under the Department of Health and Human Services, with a NAICS code of 541715 for research and development in the physical, engineering, and life sciences. All inquiries should be directed to the Common Fund RNomics Program at cfrnomics@od.nih.gov, and further details can be found through the grants.gov listing. The forecast notice was posted on August 5, 2026, with no set-aside designation or specific place of performance indicated.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

9 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
RNomics Technology Enhancement CentersThe NIH Common Fund, in collaboration with multiple NIH Institutes and Centers, is preparing to issue a funding opportunity for the RNomics program, specifically targeting the establishment of Technology Enhancement Centers (RTECs) aimed at advancing tools for comprehensive RNA analysis. These centers will build upon existing technologies with proven feasibility to improve methods for measuring, mapping, and testing RNA molecules across cells and tissues, with a focus on delivering practical, widely accessible enhancements. Key priorities include end-to-end RNA sequencing, quantitative mapping of RNA modifications, and integrated analysis of RNA sequence, structure, modification, interactions, localization, dynamics, and function, as well as the development of molecular and biochemical tools for RNA manipulation and functional validation. The RTECs are one component of the broader RNomics initiative, which also encompasses transformative technologies, molecular standards, and a coordinating center, all designed to enable a holistic understanding of the RNome and its role in health and disease. While applications are not currently being accepted, this forecast notice provides advance notice to help potential applicants form strong collaborations and refine project proposals. The opportunity is listed under NAICS code 541715, sponsored by the National Institutes of Health under the Department of Health and Human Services, with inquiries directed to the Common Fund RNomics Program at cfrnomics@od.nih.gov and further information available via the Grants.gov portal.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

9 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
RNomics Molecular StandardsThe NIH Common Fund, in collaboration with multiple NIH Institutes and Centers, is preparing to issue a funding opportunity for the RNomics Molecular Standards initiative, part of the broader RNomics program aimed at advancing the study of the complete RNA landscape in biological systems. This initiative will focus on developing, testing, refining, and distributing molecular reference standards for RNA modifications, including modified nucleosides and oligonucleotides, to ensure accurate, reproducible, and comparable results across diverse research platforms and laboratories. The standards will serve as benchmarks for evaluating RNA detection and analysis technologies and will be accompanied by guidance on their optimal selection and application, with plans in place for their sustained availability beyond the funding period. While applications are not currently being accepted, this forecast notice alerts the research community to an upcoming opportunity to engage in creating critical resources that will underpin the entire RNomics program. The standards developed under this initiative will support the broader goals of enhancing scientific rigor, facilitating cross-laboratory validation, and enabling the integration of multi-omic RNA data. The funding opportunity is administered by the National Institutes of Health under the Department of Health and Human Services, with inquiries directed to the Common Fund RNomics Program via cfrnomics@od.nih.gov and a North American Industry Classification System code of 541715. The posting date indicates this forecast is active as of August 5, 2026, and interested parties are encouraged to build collaborations and prepare proposals in advance of the formal solicitation.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

9 days ago

DEADLINE

N/A
View Details
NAICS: 519290
Grant
RNomics Outreach and Coordination (ROC) CenterThe NIH Common Fund, in collaboration with other NIH Institutes and Centers, is preparing to launch the RNomics program to advance the study of the complete RNA landscape in biological systems, encompassing sequences, modifications, structures, locations, interactions, and functions. This initiative will foster the development of transformative tools and resources to enable integrated analysis of the RNome, with the goal of deepening understanding of human health and disease. The program will consist of four components: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center, though no applications are currently being accepted. This notice serves to inform potential applicants and encourage the formation of collaborations and robust research proposals ahead of future funding opportunities. The RNomics Outreach and Coordination (ROC) Center will act as the central hub for the consortium, responsible for data management, community engagement, and cross-project coordination. It will build and maintain a centralized data portal, establish and promote standardized data formats, coordinate the validation and benchmarking of RNA technologies, and lead large-scale data analyses across the program. The ROC Center will also drive outreach, training, and resource sharing initiatives to broaden adoption of RNomics tools and ensure the long-term accessibility and sustainability of all generated data assets. The National Institutes of Health, under the Department of Health and Human Services, is the issuing agency, with inquiries directed to the Common Fund RNomics Program via cfrnomics@od.nih.gov, and the forecasted posting date for the official solicitation is August 5, 2026.
Web Search Portals and All Other Information Services

POSTED

9 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)The National Institutes of Health is issuing a single-source solicitation to continue the DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study. This multi-center longitudinal consortium operates across 19 clinical sites to investigate the biological mechanisms and risk factors associated with youth-onset type 2 diabetes, specifically focusing on high-risk youth during early puberty. The contract supports the Biostatistics Research Center, which acts as the central coordinating hub for the project. This center is responsible for managing data, ensuring quality assurance, overseeing statistical design and analysis, and coordinating protocol implementation across all sites to maintain the integrity of the longitudinal dataset and achieve the study's scientific objectives.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

10 days ago

DEADLINE

N/A
View Details