This Government Contract opportunity from Department Of Agriculture was posted on April 18, 2022. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Rice Transformation Service

Awarded

12405B22Q0079Federal

Submission Closed04/18/2022, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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National Institutes Of Health

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DEADLINE

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Solicitation # RFA-AI-28-012

The National Institute of Allergy and Infectious Diseases (NIAID) has issued solicitation RFA-AI-28-012 to establish a consortium of Translational Centers Using Microphysiological Systems for Infectious Diseases (TCMID). The primary objective is to refine and validate human tissue models using Microphysiological Systems (MPS) to a level consistent with regulatory qualifications, thereby promoting their adoption by product developers and reducing reliance on laboratory animals. This initiative aligns with NIH and FDA guidance on New Approach Methodologies (NAMs) to accelerate the development of safer medical interventions by capturing human variability and patient-specific characteristics. The program is structured around an Administrative Core, a Qualification Core, and Scientific Cores, with a heavy emphasis on technical readiness, reproducibility, and regulatory acceptance. Key deliverables include the validation of assays for specific endpoints and the submission of regulatory packages. Applicants must be domestic entities, as foreign organizations and foreign subawards are strictly prohibited. Required personnel must possess deep expertise in infectious diseases, MPS platforms, bioinformatics, and FDA submission processes. Applications are due by January 29, 2027, and must be submitted via the NIH ASSIST system or approved institutional system-to-system solutions. Evaluation is based on an overall impact score considering the project's significance, the suitability of the investigators, and the quality of the institutional environment. Mandatory application components include a Data Management and Sharing Plan and a Benchmarks and Timeline PDF not exceeding six pages. Awardees must also adhere to strict cybersecurity incident reporting guidelines, notifying HHS within 48 hours of any discovery.

National Institutes Of Health

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DEADLINE

Immune Tolerance Network (UM1 Clinical Trial Required)

Solicitation # RFA-AI-28-005

The National Institutes of Health, under the Department of Health and Human Services, is seeking applications through solicitation RFA-AI-28-005 to continue the Immune Tolerance Network (ITN). This cooperative agreement aims to develop tolerogenic therapies for immune-mediated disorders, specifically focusing on autoimmune diseases, allergic diseases and asthma, and the immune-mediated consequences of transplantation. The network operates through four integrated functional areas: Leadership, Clinical Operations, Core Laboratory, and Bioinformatics. Its primary objectives include designing and conducting clinical trials, performing integrated mechanistic studies, and sharing research results. Eligible applicants include small businesses and other for-profit organizations, though non-domestic entities are ineligible. Applications are evaluated based on scientific and technical merit, with a primary focus on significance and the likelihood of exerting a sustained influence on the research field. Key requirements include maintaining active registrations in SAM.gov, eRA Commons, and Grants.gov, as well as adhering to strict cybersecurity incident reporting and human subject protection protocols. The project requires a minimum effort of 3.6 person months per year for the PD/PI and mandates participation in a kick-off meeting in Bethesda, Maryland, and bi-annual steering meetings. Applications must follow specific page limits for the research strategy subsections and include detailed plans for clinical trial implementation, data management, and biorepository services.

National Institutes Of Health

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Pre-Clinical Models of Infectious Diseases

Solicitation # 75N93027R00003

The National Institute of Allergy and Infectious Diseases (NIAID) is issuing a ramp-on solicitation to award multiple IDIQ base contracts for the Preclinical Models of Infectious Diseases program. This initiative aims to expand the existing pool of contractors capable of developing and refining animal and animal replacement models to evaluate medical countermeasures, such as vaccines, therapeutics, and diagnostics. The program bridges the gap between in vitro testing and clinical evaluation, supporting regulatory submissions and the advancement of countermeasures against priority biodefense and emerging infectious agents. Successful offerors will be eligible to compete for task orders across four specific areas: Small Animal Models, Non-Human Primate Models, Animal Replacement and Non-traditional Animal Models, and the Generation and Distribution of Specialized Reagents. The scope of work emphasizes a wide array of pathogens, including pandemic-potential RNA viruses, antimicrobial-resistant infections, fungal diseases, and neglected tropical diseases. Proposals must be submitted electronically via the NIAID eCPS website, and applicants are required to have a valid NIH eRA Commons account for authentication and secure transmission.

National Institutes Of Health Niaid

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Alternative Protein Technologies for Military Field Feeding

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USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology

Solicitation # USDA-NIFA-TOPIC-8.2

The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.

National Institute of Food and Agriculture

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DEADLINE

Artificial Blood and Medical Consumable InnovationThe Artificial Blood and Medical Consumable Innovation subcontract supports the Defense Advanced Research Projects Agency within the Department of Defense. The scope of work involves providing innovative medical consumables and conducting biochemical research specifically focused on the development of artificial blood for prime contractors on DARPA Biological Technologies Office projects. The contractor is responsible for engineering scalable manufacturing processes for these consumables using sterile manufacturing facilities and bio-reactors. Key deliverables include the production of artificial blood prototypes and the implementation of scalable medical consumable solutions. This effort falls under NAICS code 541714, with a response deadline set for November 15, 2026.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Pre-Award Synopsis Texas Shield

Solicitation # DARPA-SN-27-07

The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), intends to enter into an agreement with The University of Texas System consortium of universities for the Texas Shield Program. This integrated research initiative, identified by solicitation number DARPA-SN-27-07 and NAICS code 541714, focuses on developing autonomous and semi-autonomous medical technologies and scalable solutions for critical medical consumables. The primary goal is to support lifesaving medical care in contested, austere, and resource-limited environments. Key technical areas of focus include autonomous medical and robotic surgical systems, casualty evacuation, artificial-blood and supply innovation, AI-enabled clinical decision support, and mass-casualty science and simulation. This notice is a pre-award synopsis and is not a request for proposals or a competitive solicitation. Interested entities are invited to submit information by November 15, 2026, to TexasShieldxBTO@darpa.mil detailing their technical expertise, integrated research infrastructure, clinical-validation capabilities, and multi-institutional coordination capacity. Additionally, respondents must describe their consortium organizational structure, commercialization capabilities, facility clearance levels, and their ability to handle Controlled Unclassified Information. The government will not reimburse any costs associated with the preparation or submission of information in response to this notice.

Defense Advanced Research Projects Agcy

POSTED

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Q--AMPLICON SEQUENCING SERVICES

Solicitation # 140G0226Q0047

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Ofc Of Acquisition Grants-Denver

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RFI Lupus Research Program (LRP) Public

Solicitation # HT9427RFI2027LRP

The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information regarding the Lupus Research Program for fiscal year 2027. This action is strictly for information and planning purposes to identify future research focus areas and funding opportunities; it is not a solicitation, and no contracts will be awarded based on this announcement. The program aims to cure lupus by funding research to improve diagnosis, prevention, and treatment, with a specific focus on understanding biological or genetic patient subsets, disease mechanisms, and enhancing overall patient quality of life. Interested parties from academia, industry, non-profit organizations, and the public are invited to provide feedback on critical research gaps and underfunded areas. Responses must be submitted via Survey Monkey by November 16, 2026. While historical appropriations from fiscal years 2017 through 2024 and 2026 totaled 75 million dollars, funds for fiscal year 2027 have not yet been appropriated. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal, as the government cannot protect such data, and all costs associated with responding to this request are the responsibility of the participant.

Defense Health Agency

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DEADLINE

Clinical Trial Site Operations and Participant ManagementThis subcontract for Clinical Trial Site Operations and Participant Management supports prime contractors on NIH/NIDDK projects through the direct execution of clinical trials. The scope of work includes recruiting and enrolling study participants, implementing lifestyle intervention weight loss programs, and conducting scheduled study visits and clinical procedures. To ensure compliance and quality, the provider must maintain IRB approval, active SAM/eRA Commons registration, and utilize specialized clinical trial facilities equipped with medical-grade ultra-low temperature freezers for biospecimen storage. The primary deliverables for this engagement consist of completed participant visits, curated patient data, and the collection of biospecimens. This opportunity is associated with NAICS code 541714 and falls under the jurisdiction of the National Institutes of Health within the Department of Health and Human Services. The response deadline for this requirement is November 17, 2026.

National Institutes Of Health

POSTED

DEADLINE

replacement skidsteerutility vehicle and attachmentsThe US Geological Survey, under the Department of the Interior, is forecasting the acquisition of a replacement skidsteer utility vehicle and associated attachments. This procurement is intended to support the National Wildlife Health Center located in Madison, Wisconsin, specifically benefiting the Midcontinent Region and Ecosystems Mission Area. The project is categorized under NAICS code 541714 and is listed as a forecast with a posted date of October 14, 2026. Sean Jones serves as the primary point of contact and small business specialist for this requirement.

US Geological Survey

POSTED

7 days ago

DEADLINE

N/A

AI Contract Overview

Solicitation 12405B22Q0079 is a request for quotation issued by the U.S. Department of Agriculture, Agriculture Research Service, Natural Products Utilization Research Unit located in University, Mississippi. The agency is seeking a contractor to provide specialized rice plant transformation services under NAICS code 541714. The primary objective is the generation of five rice transformed lines using indica IR 64 rice transformation to support ongoing research on momilactone, a natural product being studied for the discovery and development of natural product-based pesticides. The project is expected to span a duration of 6 to 9 months, resulting in the delivery of 3 to 5 individual plantlets with confirmed presence of the transgene. To be considered for the award, offerors must submit a completed and signed SF-18, maintain active DUNS and SAM.gov registrations, and comply with specific FAR provisions and clauses. Quotations must be submitted electronically to the designated point of contact, with a delivery date for the services established for February 2, 2023.

General Info

Agency

Department Of Agriculture → USDA Ars Sea Aao Acq/per Prop

Contract Value

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

University, MS, 38677, USA

Set-Aside

NONE

Awardee

UNIVERSITY OF MISSOURI

Award Issued Date

04/18/2022, 12:00:00 AM UTC

Documents

Performance of Work Statement - Solicitation 12405B22Q0079

sow

High

RFQ 12405B22Q0079 - Rice Plant Transformation Services

rfq

High

AI Contract Breakdown

Uniform Contract Format

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Timeline

PhaseAwarded

PostedApr 7

Combined Synopsis

AwardedApr 18

Contract was awarded

Submission Closed

04/18/2022, 12:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Agriculture → USDA Ars Sea Aao Acq/per Prop

Contacts2 people available

OfficeSTONEVILLE, MS, 38776, USA

Organization / AgencyDepartment Of Agriculture → USDA Ars Sea Aao Acq/per Prop

Office AddressSTONEVILLE, MS, 38776, USA

Contacts

Monte Jordan

Joanna Bajsa-Hirsche

Full Description

This is a combined synopsis/solicitation for commercial service prepared in accordance with the format in FAR 12.603 Streamlined solicitation for commercial products or commercial services, and FAR Part 13, Simplified Acquisition Procedures, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued. The solicitation number is 12405B22Q0079 and is issued as a request for quotation (RFQ). The associated NAICS Code is 541714 - Research and Development in Biotechnology (except Nanobiotechnology). This solicitation document incorporates those provisions and clauses in effect through Federal Acquisition Circular 2022-04. Description of Work: The U.S. Department of Agriculture, Agriculture Research Service, Natural Products Utilization Research Unit (NPURU), University, MS location has a requirement seeking contractor to provide rice plant transformation services which include the generation of five rice transformed lines with indica IR 64 rice transformation. With the service, over 6-9 months 3-5 individual plantlets with confirmed presence of transgene will be delivered. The transgenic lines are necessary for the continuation of research on a natural product - momilactone. The project is a part of the mission of USDA/ARS/NPURU, University, MS location focusing on natural product-based pesticides discovery and development. DOCUMENTS TO BE INCLUDED IN QUOTE: In order to be considered for award, Offerors shall respond by submitting: One (1) original fully completed and signed SF-18 (complete Blocks 13, 14, 15, and 16); include unit price and total amount for each CLIN listed, quotation should be valid for at least 60 days after receipt of quotation. Providing all associated documents identified in the attached clauses and provisions document, specifically 52.212-1 Instruction for the Preparation of Offers. Have an active DUNS and SAM.gov registration and complete the Representations in FAR 52.204-24 prior to submission of quotation; the Representation and Certification section should also be completed electronically in the System for Award Management (SAM) at www.beta.sam.gov. Failure to provide the required information in the requested format may result in quotes not being considered for award. FAR clauses 52.212-1, 52.212-2, 52.212-3, 52.212-4 and 52.212-5 (and any addenda to those clauses) are included in the attached clauses and provisions document. Additionally, other contract requirements and terms/conditions can be located in the same document. All interested firms wishing to furnish a quotation shall furnish a quotation by Thursday, April 14, 2022, no later than 3:00 p.m. Central Time (CT). Quotations are to be sent via email to Monte Jordan @ monte.jordan@usda.gov. Only Email submissions of quotations will be accepted. All questions pertaining to this solicitation must contain reference to the solicitation number and must be submitted, in writing only via e-mail to monte.jordan@usda.gov no later than April 12, 2022. No telephone inquiries will be accepted. Any amendment and documents related to this procurement will be available electronically at the Government Point of Entry (beta.sam.gov).

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