Specialized Alcohol Research Centers (P50 Clinical trial Optional)

The National Institutes of Health, through the National Institute on Alcohol Abuse and Alcoholism, is soliciting applications for Specialized Alcohol Research Centers (P50) under solicitation RFA-AA-28-001. This grant program is designed to support interdisciplinary, collaborative research focused on alcohol misuse, Alcohol Use Disorder, and related health consequences across the lifespan. The primary objective is to establish a critical mass of researchers in innovative or understudied areas, providing leadership in research methodology and mentorship for young investigators. The program emphasizes the creation of centers that serve as regional and national resources, contributing more to the field than the sum of their individual parts. The NIAAA intends to commit 1.5 million dollars in FY 2027 to fund up to one award, with a maximum direct cost limit of 1.15 million dollars per year for a project period of up to five years. Applications are evaluated based on scientific and technical merit, specifically focusing on significance and the quality of the research environment. For those proposing clinical trials, additional scrutiny is applied to the trial protocol, data management, and participant safety. The award is governed by 42 CFR Part 52 and the Public Health Service Act, with strict requirements for SAM registration, UEI, and eRA Commons accounts. Key administrative requirements include the establishment of a Program Advisory Committee of at least five external members and adherence to the Cybersecurity Act of 2015, which requires incident reporting within 48 hours of discovery. The response deadline for this solicitation is January 27, 2027.