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Stable Cell Line Development

Active

Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Food and Drug Administration is seeking stable cell line development to support the validation of a specific method requiring increased quantities of purified mAb-G and mAb-NG. Because current production yields from mouse hybridomas are insufficient, the project focuses on creating three stable cell lines to express recombinant versions of these antibodies. The scope of work specifically requires the development of a full-length form for mAb-G, as well as both full-length and single-chain forms for mAb-NG. This forecast is managed by the FDA's Center for Drug Evaluation and Research acquisition team to ensure a reliable supply of these materials for ongoing validation efforts.

General Info

FDA seeks three stable cell lines to produce recombinant mAb-G and mAb-NG antibodies.

Agency

Food and Drug Administration → Food And Drug Administration

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

USA

Set-Aside

NONE

Documents

0

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Documents will appear here when they are available.

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Organization & Contact Information

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AgencyFood and Drug Administration → Food And Drug Administration

Contacts2 people available

OfficeN/A

Organization / AgencyFood and Drug Administration → Food And Drug Administration

Office AddressN/A

Contacts

Cder Acquisition Liaison

contact@example.gov

To Be Determined To Be DeterminedContracting Officer

Full Description

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The ongoing work is to validate the method, which will require larger quantities of purified mAb-G and mAb-NG. Due to the low production yield of mAb-G and mAb-NG from available mouse hybridomas, 3 stable cell lines expressing recombinant mAb-G and mAb-NG - full-length form for mAb-G only, and both full-length and single-chain forms for mAb-NG- are needed.

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