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This Government Contract opportunity from Department Of Energy was posted on May 11, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

TECHNOLOGY LICENSING OPPORTUNITY: Plane-Wave Ultrasound Tomography for Cancer Imaging

Closed
S-133625Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 334510
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POSTED

1 day ago

DEADLINE

in 5 days
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POSTED

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Ocular Scanner
Solicitation # W91CRB-26-AWSP-Scanner-Ultrasonic-Ocular-RPP
The Portfolio Acquisition Executive Maneuver Ground Project Manager Maneuver Medical Systems is soliciting prototype proposals for a Scanner Ultrasonic Ocular device under Other Transaction Authority pursuant to 10 U.S.C. 4022. The objective is to award two prototype agreements for the delivery and demonstration of FDA-approved commercial solutions that provide anatomical visualization and diagnostic imaging of the eye, specifically for the anterior and posterior segments. Awardees are required to deliver four prototype units within 45 to 60 days of award for operational and environmental testing conducted in accordance with MIL-STD-810H. The estimated period of performance is twelve months, with awards expected around the first quarter of fiscal year 2027. The procurement utilizes a comparative best-value methodology, prioritizing technical approach, performance compliance, reliability, schedule realism, and past performance over cost. Key requirements include Trade Agreements Act compliance, MIL-STD-130N marking for hardware, and the provision of ruggedized transport cases. Deliverables encompass the hardware units, comprehensive user and maintenance manuals, cybersecurity documentation, and on-site operator training. Proposals must be submitted as four separate PDF volumes via DoD SAFE or secure email by November 12, 2026. This action is a direct Other Transaction Agreement and is not subject to the Federal Acquisition Regulation or Defense Federal Acquisition Regulation Supplement.
W6QK Acc-Apg

POSTED

2 days ago

DEADLINE

in 14 days

AI Contract Overview

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Plane-wave ultrasound tomography developed by Los Alamos National Laboratory represents a transformative advancement in medical ultrasound imaging, specifically engineered to enhance tissue characterization for the detection and monitoring of prostate and breast cancer. Unlike conventional ultrasound systems that primarily generate structural images, this technology reconstructs quantitative physical properties of tissue using plane-wave ultrasound data, incorporating both transmission and reflection signals to deliver deeper, more accurate insights into tissue composition. It leverages innovations such as wave-energy-based preconditioning, spatial and edge regularization, and super-resolution TR-MUSIC techniques to significantly improve image resolution, reconstruction stability, and computational efficiency, overcoming key limitations in diagnostic clarity and consistency that plague standard ultrasound methods. The platform is designed for broad clinical utility across screening, diagnosis, and treatment monitoring, offering improved diagnostic confidence and the potential to extend ultrasound’s role beyond imaging into quantitative tissue analysis. Suitable for use in hospitals, imaging centers, and specialized clinics, it targets critical areas in women’s health and urology while remaining adaptable to other diseases. With a Technology Readiness Level of 5, the technology is at an advanced stage of development and is supported by multiple issued U.S. patents. Los Alamos National Laboratory is seeking commercial partners through exclusive or non-exclusive licensing agreements to bring this innovation to market, with interested parties encouraged to engage via the provided licensing contact to explore collaboration opportunities that can transform cancer imaging workflows and expand the clinical value of ultrasound technology.

General Info

Los Alamos offers advanced plane-wave ultrasound technology improving cancer imaging and tissue characterization.

NAICS

334510 - Electromedical and Electrotherapeutic Apparatus Manufacturing

Place of Performance

NM, 87545, USA

Set-Aside

NONE

Documents

0

No documents available

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Timeline

PhaseClosed
Posted

special-notice

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Energy → Triad - DOE Contractor
Contacts2 people available
OfficeColumbus, OH, 43201, USA
Office AddressColumbus, OH, 43201, USA
Contacts
Caleb Ledgerwood
Lindsay Augustyn

Full Description

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Plane-wave ultrasound tomography from Los Alamos National Laboratory is a next-generation imaging platform designed to improve how tissue properties are reconstructed from ultrasound data, with a focus on detecting and characterizing prostate and breast cancer. The related invention disclosures describe a broader ultrasound toolkit that includes ultrasound waveform tomography/inversion, efficiency improvements and super-resolution imaging methods, creating a platform that can deliver more informative imaging while remaining practical for screening, diagnosis and treatment monitoring.


The Challenge
Early cancer detection depends on imaging methods that can reliably distinguish suspicious tissue from healthy tissue, yet the disclosures note that effective imaging for dependable cancer detection and characterization remains limited. Current clinical ultrasound can be useful, but they often limited in their ability to provide sufficient detail about tissue properties, and they can be constrained by image resolution and quality. The inventors addressed a critical clinical need for ultrasound imaging that can perform more than generating an image—they need to help characterize the nature of the tissue itself.


Problems Solved
The plane-wave tomography platform addresses these limitations by reconstructing tissue properties from plane-wave ultrasound data, rather than relying only on conventional image formation. These technologies also describe methods that improve reconstruction speed, stability, and resolution, including wave-energy-based preconditioning, spatial and edge regularization, and super-resolution TR-MUSIC techniques. Together, the technology bundle is intended to produce more accurate, higher-quality, and quantitative imaging that can better support cancer detection and characterization.


The broader problem solved by the Plane-Wave platform is the gap between conventional ultrasound imaging and clinically useful tissue characterization. Prostate and breast cancer detection benefit from imaging that is more sensitive to changes in tissue physical properties and more robust across different scanning conditions. These methods are designed to help imaging systems deliver more consistent results, improve diagnostic confidence, and extend the value of ultrasound into areas where existing methods may not provide sufficient information.


Advantages


  • Better tissue characterization than standard ultrasound
  • Can use transmission data, reflection data, or both
  • Supports prostate cancer and breast cancer applications, in addition to other diseases
  • Aims to improve image quality and resolution while providing additional tissue-property information
  • Helps with screening, diagnosis and treatment monitoring
  • Includes related methods that improve reconstruction stability and efficiency

Market Applications


  • Medical and Diagnostic Imaging (ultrasound systems for hospitals and imaging centers, tissue characterization and lesion assessment)
  • Cancer Screening (prostate and breast cancer detection programs)
  • Treatment Monitoring (tracking response during therapy)
  • Women’s Health (breast imaging and follow-up evaluation)
  • Urology (prostate imaging and assessment)


TRL 5


S-133625.001


US Patent Nos. 9,955,943; 9,955,944; 10,028,728; 11,344,283; 10,034,656; 10,231,707; 11,284,858


LA-UR-26-23851



LANL Tech Partnerships: Unlock the Innovative Potential


Los Alamos National Laboratory offers a wide range of cutting-edge technologies and capabilities that may provide your company with a competitive edge in the market and unlock the innovative potential that can enhance, refine, and revolutionize your products.


LANL’s licensing program focuses on moving inventions developed by our researchers to commercial innovations. Patented and patent pending inventions and copyrighted software are available to existing and start-up companies through exclusive and non-exclusive licensing agreements. For specific discussions, please contact contact@example.gov.


Note: This is not a call for external services for the development of this technology.


https://www.lanl.gov/engage/collaboration/feynman-center/partner-with-us/licensing-technology


m.lanl.gov/tech-search

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