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The contract would be to run guideline and non-guideline oral dose in vivo toxicity studies in rodents.�The scope of the contract includes chemical procurement, verification of chemical purity, dosin…

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The Environmental Protection Agency is seeking a contractor to conduct both guideline and non-guideline oral dose in vivo toxicity studies using rodent models. The comprehensive scope of work encompasses the entire study lifecycle, including the procurement of chemicals, verification of chemical purity, and the evaluation of dosing solution stability. Additionally, the contractor will be responsible for performing dose range finding studies and repeat dose toxicity studies. These projects may be conducted under both GLP and non-GLP standards to ensure regulatory compliance where necessary. The evaluation of toxicity will involve a combination of traditional endpoints, such as histopathology, and non-traditional endpoints, including transcriptomics, to provide a detailed analysis of the chemical effects.

General Info

EPA seeks contractor for rodent oral dose toxicity studies using GLP and non-GLP standards.

Agency

Environmental Protection Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

PostedJan 1

forecast

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Organization & Contact Information

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AgencyEnvironmental Protection Agency

ContactsNo contacts available

OfficeN/A

Organization / AgencyEnvironmental Protection Agency

Office AddressN/A

ContactsNo contact information available

Full Description

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The contract would be to run guideline and non-guideline oral dose in vivo toxicity studies in rodents.�The scope of the contract includes chemical procurement, verification of chemical purity, dosing solution stability evaluation, dose range finding studies, and repeat dose toxicity studies.�The studies may include GLP and non-GLP studies, traditional endpoints (e.g., histopathology), and non-traditional endpoints (e.g., transcriptomics).

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