This Combined Synopsis/Solicitation opportunity from Department Of Commerce was posted on August 4, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Ultrafast Microscope Camera
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The National Institute of Standards and Technology, within the Department of Commerce, is seeking innovative solutions to advance the characterization of gene delivery nanoparticles through the development of ultrafast microscope camera technology. This effort supports the gene therapy manufacturing innovations in measurement sciences project under the Biosystems and Biomaterials Division, aimed at addressing critical heterogeneity challenges in viral and non-viral gene therapy vectors. The goal is to enable rapid, high-precision, multi-attribute measurements of individual nanoparticle physical properties using light-scattering microscopy, thereby accelerating the development and ensuring the safety and efficacy of next-generation gene therapies. The project will focus on enhancing measurement science tools to provide detailed, single-particle analysis that current methods cannot achieve reliably or quickly. The contract, identified by solicitation number 1333ND26QNB640413, is open for responses until August 14, 2026, with a posted date of August 4, 2026. It falls under NAICS code 334516 and is categorized as a combined opportunity with no set-aside designation. All performance will occur in Gaithersburg, Maryland, where the Material Measurement Laboratory is located. Primary point of contact is Rene D. Edwards, reachable at rene.edwards@nist.gov or 301-975-6107, with Robert Singman as the secondary contact at robert.singman@nist.gov or 301-975-6388. Interested parties must submit proposals through the SAM.gov portal linked in the contract details.
General Info
Contract Value
$46,753.45Place of Performance
Gaithersburg, MD, 20899, USASet-Aside
Awardee
SCIENTIFIC IMAGING, INC.Award Issued Date
Timeline
Submission Closed
Organization & Contact Information
Full Description
The gene therapy manufacturing innovations in measurement sciences (IMS) project, in the Biosystems and Biomaterials Division, within the Material Measurement Laboratory of the National Institute of Standards and technology, pursues the goal of developing light scattering microscopy methods to characterize gene delivery particles. Emerging gene therapy treatments use gene delivery nanoparticles, such as viral vectors and non-viral carriers, to cure intractable diseases. These manufactured particles suffer heterogeneity issues that hinder treatment efficacy and safety. This project aims to develop light-scattering microscopy methods to enable rapid, multi-attribute measurements of individual gene therapy nanoparticles’ physical characteristics. Such measurements will speed the development of new gene therapy treatments and improve their efficacy and safety.
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