This Government Contract opportunity from Department Of Health And Human Services was posted on September 14, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

WGS Bioinformatics and Variant Calling Services

Closed

Federal

Submission Closed09/24/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

International

Clinical Evidence Review for Medical Gas Waste MitigationThis subcontract for NHS England involves a Clinical Evidence Review for Medical Gas Waste Mitigation. The selected provider will perform a comprehensive analysis of national and international evidence concerning oxygen and nitrous oxide waste to support prime contractors on healthcare research projects. Key responsibilities include conducting detailed literature reviews of clinical journals and international healthcare standards, as well as analyzing patterns in medical gas usage and waste. To complete the scope of work, the contractor must utilize medical databases such as the Cochrane Library and PubMed to produce a final comprehensive evidence review report. The opportunity was posted on November 2, 2026, with a response deadline of November 16, 2026. The project falls under NAICS code 541715.

POSTED

DEADLINE

Bioinformatics Analysis and Data ManagementThis subcontract, titled Bioinformatics Analysis and Data Management, provides specialized bioinformatics support for prime contractors working on NIH and NIEHS projects. The scope of work involves processing raw sequencing reads into usable data and performing detailed genomic analysis for human, rodent, and yeast samples. To achieve this, the contractor will utilize high-performance computing clusters and bioinformatics software pipelines while adhering to strict data confidentiality standards. Final deliverables include processed data files and comprehensive analyzed sequencing data reports. The project is associated with the National Institutes of Health Olao under the Department of Health and Human Services, with the place of performance located in Durham, North Carolina. Identified by NAICS code 541715, the opportunity was posted on November 2, 2026, with a response deadline of November 12, 2026.

National Institutes Of Health Olao

POSTED

DEADLINE

Solicitation # DARPA-PS-27-06

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Area of Interest: OSW Cost Assessment and Program Evaluation (CAPE) Modeling and Simulation

Solicitation # HQ003427AOI5

The Washington Headquarters Services is soliciting innovative commercial solutions under solicitation HQ003427AOI05 to establish a next-generation modeling and simulation architecture for the Office of the Secretary of War Cost Assessment and Program Evaluation. The objective is to replace legacy infrastructure with a unified computational backbone that compresses the cycle time between budget queries and warfighting insights. This architecture must integrate three functional layers: a high-performance simulation execution layer for large-scale model runs, a machine-learned surrogate emulation layer for hosting government-developed models, and an intuitive self-service quantitative analysis layer for visualization and sensitivity analysis. The technical requirements specify a high-performance compute environment capable of executing between 1,200 simulations in 10 hours for light cases and up to 150,000 simulations within two weeks for heavy cases. The system must operate at Impact Level 6, support network throughput between 100 Mbps and 1 Gbps, and be accessible from the Pentagon and Mark Center. It must accommodate a diverse software ecosystem including Python, R, Java, PyTorch, and large language models. While the government will retain exclusive operational tenant administration and control over data and security permissions, the commercial provider will be responsible for turnkey managed IT operations, including hardware availability, patching, and cybersecurity hardening. Interested respondents must submit white papers by November 12, 2026, in accordance with Commercial Solutions Opening procedures.

Washington Headquarters Services

POSTED

DEADLINE

NSEETS Contract Ceiling Increase for Continued NASA Support

Solicitation # 80GSFC19D0011-Synposis

NASA Goddard Space Flight Center

POSTED

DEADLINE

Mathematical Algorithm Development and Computational Analysis in Support of MDA Flight Test Support

Solicitation # MDA26ABRFI01

Missile Defense Agency (mda)

POSTED

DEADLINE

Tactical Resupply Unmanned Aircraft System Increment II Cargo UAS Industry Demonstration

Solicitation # NAWCAD-SN-26-TRUASII

The Direct Reporting Portfolio Manager for Robotic and Autonomous Systems 4.0, Air Warfare Program Management Office, is seeking industry participants for the Tactical Resupply Unmanned Aircraft System (TRUAS) Increment II Cargo UAS industry demonstration. Scheduled for January 25 through February 5, 2027, in Huntsville, Alabama, this event aims to identify unmanned aircraft systems (UAS) and enabling technologies to support the Marine Corps Unmanned Logistics System – Air (ULS-A) mission for last-mile tactical distribution in expeditionary environments. The government is inviting applications from all qualified participants, including small businesses and non-traditional defense contractors, provided they are U.S. citizens or companies with U.S.-based offices. Participants must demonstrate a UAS with a maximum gross take-off weight of up to 350 lbs that can perform specific autonomous flight missions. These include a 40 nautical mile round trip with a 100 lb payload and a 10 nautical mile round trip with at least a 150 lb payload, both without refueling. Systems must maintain an airspeed of at least 50 knots, operate below 1,000 feet AGL, and launch and recover without mechanical assistance. Technical requirements include FIPS 140-3 Level 2 radio encryption, compliance with MIL-STD461G and MIL-STD464C, and the ability to operate in degraded environments using alternative positioning, navigation, and timing (PNT) solutions. Selection for the demonstration is based on a white paper and questionnaire evaluated against a specific rubric focusing on country of origin, weight, range, payload capacity, and unit cost. Successful performance during the demonstration may lead to the award of an Other Transaction (OT) prototype agreement under 10 U.S.C. section 4022, which could potentially result in a follow-on production contract without further competition. To be eligible for such an award, selectees must join the Naval Aviation Systems Consortium (NASC). Applications are due by November 30, 2026.

Naval Air Warfare Center Air Division

POSTED

DEADLINE

Building America Subject Matter Expert Technical Support

Solicitation # RFP-2026-10245()

The National Laboratory of the Rockies (NLR) is soliciting proposals under RFP-2026-10245 to engage technical subject matter experts (SMEs) in support of the Department of Energy's Building America program. The scope of work focuses on two primary areas: new construction support, which emphasizes factory optimization, product design, materials innovation, and digital modeling to lower costs and increase speed of construction; and envelope retrofits, which aims to reduce utility bills and first costs by addressing moisture, humidity, and infiltration. SMEs will be responsible for research, field validation, data collection, industry analysis, and knowledge transfer to provide actionable guidance to industry stakeholders. The procurement seeks up to ten firm fixed price subcontracts, each featuring a 12-month basic period with four 12-month options, for a total potential duration of 60 months. Each agreement has an anticipated annual ceiling of 100,000 dollars and a five-year ceiling of 500,000 dollars. Awards are based on best value, with a heavy emphasis on qualitative merit—specifically technical expertise, research capabilities, collaboration, and knowledge transfer—rather than price alone. Proposals must be submitted electronically in PDF format, including a technical proposal limited to 8 pages, a labor rate break-down, and required representations and certifications.

Llc - DOE Contractor Alliance For Energy Innovation

POSTED

DEADLINE

Request for Information (RFI) for a Cislunar Space System (CSS)

Solicitation # 10302026-01

The Department of the Air Force is conducting market research via a Request for Information to inform the acquisition strategy for a Cislunar Space System (CSS). The objective is the rapid development and fielding of up to five space vehicles by late CY29 to serve as seed vehicles for a potential future proliferated cislunar constellation. The system requires a comprehensive solution including spacecraft buses, a ground segment for mission management and telemetry, launch integration for government-provided National Security Space Launch boosters, and ongoing operations and maintenance. Technical requirements specify a payload capacity of up to 2,000 kg, power thresholds between 1 kW and 3 kW, three-axis stabilization with 6-DOF thruster control, and the implementation of NSA Type-I encryption. The government is seeking low-risk solutions with minimal non-recurring engineering, prioritizing buses that have flown within the last three years or will complete system-level integration within 24 months. Design life thresholds are set at three to five years with 0.6 reliability, and end-of-life disposal must comply with Orbital Debris Mitigation Standard Practices. Based on the RFI responses, the government may award up to five Firm Fixed Price preliminary design study contracts. Evaluation of respondents will focus on technical, schedule, and production risks, as well as overall execution ability and prior domain expertise in cislunar-qualified vehicles. Responses must be submitted electronically by November 13, 2026, and include a completed Summary Response Template and a technical narrative limited to fifteen pages.

Department Of The Air Force

POSTED

DEADLINE

NextGen IACMAC Industry Day - VIRTUAL

Solicitation # FA807527R0001-NextGen_IACMAC_Industry_Day

The NextGen IACMAC is a massive Indefinite Delivery Indefinite Quantity Multiple Award Contract designed as a research and development marketplace with a total ceiling value exceeding 80 billion dollars. Managed by the Department of Defense and the 774 ESS, this vehicle aims to bridge the gap between government mission problems and technical capabilities by connecting industry, academia, laboratories, and non-traditional innovators. The program focuses on a rapid cycle of discovery, competition, development, demonstration, and transition to move technology from research to relevance, emphasizing rapid prototyping and iteration. To support this effort, the government is conducting a virtual briefing on November 4, 2026, from 1400 to 1530 EST, to provide industry partners with an overview of the requirements, technical priorities, and the tentative acquisition strategy and timeline. This event serves as a follow-up to an in-person Industry Day and is intended to gather feedback on potential solutions related to Sources Sought Notice FA807527R0001. Interested companies must RSVP by 1600 EST on November 3, 2026, via email to [email hidden] with the required company and point of contact information.

POSTED

DEADLINE

Office of Hazardous Materials Safety Research Initiative – FY2026 BROAD AGENCY ANNOUNCEMENT (BAA)

Solicitation # PHMSA-26HM-BAA

The U.S. Department of Transportation's Pipeline and Hazardous Materials Safety Administration (PHMSA) is soliciting research proposals under Broad Agency Announcement PHMSA-26HM-BAA to advance safety and prevent incidents during the transportation of hazardous materials. The initiative focuses on five core topic areas: Efficient Safety Standards (26HM-ESS), Safe Energy Storage Technologies (26HM-SST), Innovative Packaging (26HM-IPG), Risk Reduction for Emergency Response (26HM-RER), and Hazardous Materials Rail Transportation Safety (26HM-RTS). Eligible applicants include U.S.-based industry, accredited universities, non-profits, and permitted federally affiliated research centers, while foreign entities may only participate as subcontractors. The selection process consists of two phases, beginning with a Phase I white paper due November 18, 2026, followed by invited Phase II full proposals. Awards will be issued as Firm-Fixed-Price or Cost-Reimbursement procurement contracts with a ceiling of $2,000,000 per independent submission and a performance period of up to 36 months. Evaluation for Phase I is based on technical merit and feasibility (35%), relevance to program mission (35%), experience and qualifications (20%), and submission quality (10%). Phase II adds cost realism as a weighted factor. Awarded contractors must provide regular progress reports, a data management plan, and a plain-language project one-pager.

693JK3 Acquisition Services Division

POSTED

DEADLINE

Space Communications and Networking (SCaN) & Tracking and Data Relay Satellite System (TDRS) Support

Solicitation # 80MSFC27ENG1026

NASA Marshall Space Flight Center is seeking capability statements from interested vendors to provide engineering team support for Space Communications and Networking, specifically focusing on mission-critical Ka-band communications services for the Tracking and Data Relay Satellite System. The anticipated period of performance is two years, requiring fewer than ten work year equivalents to perform all work on-site in Huntsville, Alabama. The scope of work covers seven major skill categories, including radio frequency communication, aerospace flight software, avionics, propulsion, and hardware testing. Interested parties, including various small business categories and minority institutions, must submit a capability statement of five pages or less by November 5, 2027. Requirements for respondents include demonstrating the ability to provide personnel with Top Secret/Sensitive Compartmented Information clearances and verifying ITAR compliance through a company statement. This sources sought notice is for market research purposes to determine competition levels and small business subcontracting goals, and it is not a formal solicitation.

NASA Marshall Space Flight Center

POSTED

about 20 hours ago

DEADLINE

in 3 days

AI Contract Overview

This subcontract for WGS Bioinformatics and Variant Calling Services supports the NIH HANDLS study projects by providing primary and secondary analysis of raw sequencing data. The scope of work involves executing read alignment and variant calling via the DRAGEN Germline pipeline, performing joint variant calling for multi-sample VCF files, and conducting essential quality control checks for contamination, duplicates, and sex. These operations are carried out using high-performance computing systems to deliver final CRAMs, gVCFs, VCFs, and structural variant or CNV calls. Managed under NAICS code 541715 for the National Institutes of Health within the Department of Health and Human Services, the project is based in Brooklyn. The solicitation was posted on September 14, 2026, with a response deadline of September 24, 2026.

General Info

Subcontract for NIH HANDLS study providing WGS bioinformatics and variant calling services.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Brooklyn, MD, 21225, USA

Set-Aside

NONE

Documents

This scope was carved out of 75N98026R00166.

The full solicitation package (5 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Whole genome sequencing for investigation of age-related chronic disease in HANDLS participants

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

PhaseClosed

PostedSep 14

subcontract

Response DeadlineSep 24

Deadline has passed

Submission Closed

09/24/2026, 01:00:00 PM UTC

Find active opportunities like this

Get full access to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Office AddressN/A

ContactsNo contact information available

Full Description

Performs primary and secondary analysis of raw sequencing data for prime contractors on NIH HANDLS study projects. Executes read alignment and variant calling using the DRAGEN Germline pipeline and performs joint variant calling for multi-sample VCF files. Conducts QC checks for sex, duplicates, and contamination. Uses high-performance computing (HPC) systems. Delivers CRAMs, gVCFs, VCFs, and structural variant/CNV calls.