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NAICS Code· 325412

Pharmaceutical Preparation Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing in-vivo diagnostic substances and pharmaceutical preparations (except biological) intended for internal and external consumption in dose forms, such as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions. Cross-References. Establishments primarily engaged in--Show more

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex manufacturing processes governed by cGMP standards, requiring validated equipment, rigorous quality control, and strict environmental controls to ensure product safety and efficacy.

254
Active Contracts
$17.1B
Total Obligations (12mo)
15.1K
Awarded Contracts (12mo)
380
Contractors Awarded (12mo)
-31.6%
YoY Growth

Industry Spending Overview

Federal obligations, top contractors and agencies, and related industry codes for NAICS 325412.

AI Industry Description

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex ma...

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex manufacturing processes governed by cGMP standards, requiring validated equipment, rigorous quality control, and strict environmental controls to ensure product safety and efficacy. In government contracting, this NAICS supports critical public health and military readiness initiatives, with agencies procuring medications for clinical use, emergency stockpiles, and deployed medical units. The industry bridges advanced chemistry, regulatory compliance, and supply chain resilience, making it a high-stakes segment within federal healthcare and defense procurement. Top contractors in this sector include ALTITUDE TECHNOLOGIES INC., MARATHON MEDICAL CORPORATION, NANOSONICS INC, LINDE GAS & EQUIPMENT INC., and BHPE LLC, representing a mix of specialized pharmaceutical manufacturers, medical device integrators, and gas supply providers supporting sterile production environments. These firms range from mid-sized primes to niche technical service providers, indicating a competitive landscape where regulatory expertise and cold-chain logistics capabilities are as critical as manufacturing scale. The Department of Health and Human Services, Department of Veterans Affairs, and Department of Defense are the primary buyers, driving demand through hospital formularies, VA pharmacy networks, and military medical readiness programs. Procurement focuses on FDA-approved therapeutics, pandemic preparedness stockpiles, and battlefield medical supplies requiring extended shelf life and transport stability. The market is characterized by high barriers to entry due to FDA oversight and cGMP compliance, but offers consistent demand from mission-critical agencies. Opportunities exist for contractors with validated manufacturing facilities, sterile compounding capabilities, and experience in federal supply chain protocols. Recent trends show increased emphasis on domestic sourcing and resilient production networks to reduce reliance on foreign active pharmaceutical ingredients.

Top Contractors

Companies with the highest total award value under NAICS 325412, ranked by dollars won.

Ranked by total awards
CompanyTotal AwardsContracts
MCKESSON CORPORATION$12.2B1,587
MERCK SHARP & DOHME LLC$1.4B30
GLAXOSMITHKLINE, LLC$580.8M8
SANOFI VACCINES US INC.$509.7M92
PFIZER INC$478.8M856
JANSSEN PRODUCTS, LP HORSHAM 19044$468.0M1
GOLDEN STATE MEDICAL SUPPLY, INC.$193.7M261
EXELAN PHARMACEUTICALS INC$182.0M106
GE HEALTHCARE INC ARLINGTON HEIGHTS 60004$104.4M1
MODERNA US, INC. PRINCETON 08540 JIB$86.7M1

Top Agencies

Federal agencies directing the most contract spending toward NAICS 325412.

Department Of Veterans Affairs1,197 awards$12.2B
Department Of Health And Human Services123 awards$3.5B
Nac Federal Supply Schedule (36F797)13 awards$583.1M
DLA Troop Support23 awards$398.3M
Department Of Justice1,760 awards$171.9M
Nac Pharmaceuticals (36E797)3 awards$96.2M
Department Of Defense11,794 awards$56.9M
262-NETWORK Contract Office 22 (36C262)16 awards$27.0M
244-NETWORK Contract Office 4 (36C244)12 awards$17.6M
W40M MRC0 West9 awards$13.1M

Related NAICS Codes

Industries similar to Pharmaceutical Preparation Manufacturing, by shared sector, subsector, and industry group.

Medicinal and Botanical Manufacturing

This U.S. industry comprises establishments primarily engaged in (1) manufacturing uncompounded medi...
325411Same Industry GroupHigh Similarity

In-Vitro Diagnostic Substance Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing in-vitro (i.e., not t...
325413Same Industry GroupHigh Similarity

Biological Product (except Diagnostic) Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing vaccines, toxoids, bl...
325414Same Industry GroupHigh Similarity

Petrochemical Manufacturing

This industry comprises establishments primarily engaged in (1) manufacturing acyclic (i.e., aliphat...
325110Same SubsectorMedium Similarity

Industrial Gas Manufacturing

This industry comprises establishments primarily engaged in manufacturing industrial organic and ino...
325120Same SubsectorMedium Similarity

Synthetic Dye and Pigment Manufacturing

This industry comprises establishments primarily engaged in manufacturing synthetic organic and inor...
325130Same SubsectorMedium Similarity

Other Basic Inorganic Chemical Manufacturing

This industry comprises establishments primarily engaged in manufacturing basic inorganic chemicals ...
325180Same SubsectorMedium Similarity

Ethyl Alcohol Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing nonpotable ethyl alco...
325193Same SubsectorMedium Similarity

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NAICS 325412 FAQ

Frequently Asked Questions

NAICS code 325412 covers Pharmaceutical Preparation Manufacturing. This U.S. industry comprises establishments primarily engaged in manufacturing in-vivo diagnostic substances and pharmaceutical preparations (except biological) intended for internal and external consumption in dose forms, such as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions. Cross-References. Establishments primarily engaged in--

Recently Posted in Pharmaceutical Preparation Manufacturing

NAICS: 325412
New
DIBBS
Pharmaceutical Packaging and PalletizationThe contract requires the packaging of Lidocaine Hydrochloride and Dextrose Injection in strict compliance with ASTM D3951 standards and RP001 specifications, ensuring pharmaceutical integrity and regulatory adherence throughout the packaging process. All units must be arranged and secured on pallets to meet military-compliant palletization requirements for shipment through the Defense Logistics Agency, with emphasis on durability, stability, and traceability during transport. The place of performance is identified as Williamsburg, Virginia, with a ZIP code of 23185-5830, indicating the physical location where the packaging and palletization activities must occur. This subcontract, categorized under NAICS code 325412 for Pharmaceutical Preparation Manufacturing, is issued by the Department of Defense through the Medical Supply Chain Pharm FSA and is open for response until July 27, 2026. The solicitation is not set aside for any specific small business or minority designation, and bids must adhere to all technical, logistical, and documentation standards mandated by military supply chain protocols. The primary objective is to deliver a fully compliant, ready-for-issue pharmaceutical product package that meets the quality and handling expectations necessary for DoD medical supply operations.
MEDICAL SUPPLY CHAIN PHARM FSA

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NAICS: 325412
New
DIBBS
Pharmaceutical Supply of NSN 6505017246289The contract is for the supply of a specific pharmaceutical item identified by NSN 6505017246289, required to meet FDA regulations and U.S. military logistics standards. The item must be accompanied by complete batch-specific documentation and packaged in accordance with military-grade requirements to ensure safety, traceability, and compliance throughout the supply chain. The procurement is structured as a subcontract under the Department of Defense, managed by the Medical Supply Chain Pharm FSA, with performance expected at Fort Bliss, Texas, in the ZIP code 79918-2527. The solicitation was posted on July 19, 2026, and responses are due by July 27, 2026, with the NAICS code 325412 indicating classification under Pharmaceutical and Biological Product Manufacturing. All submissions must align with the detailed requirements stipulated in the DIBBS system, where the full solicitation is accessible via the provided link.
MEDICAL SUPPLY CHAIN PHARM FSA

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NAICS: 325412
New
DIBBS
Medical Adhesive Applicator Manufacturing and SupplyThe contract requires the manufacture and supply of sterile, flammable medical adhesive applicators impregnated with Compound Benzoin Tincture specifically designed for surgical adhesion enhancement. All products must comply with stringent regulatory standards set by the FDA, including requirements for sterility, shelf-life stability, accurate labeling, and secure packaging to ensure safety and efficacy in clinical environments. The scope encompasses full production capability with complete quality control throughout the manufacturing process and adherence to all applicable medical device protocols. The solicitation is issued under the NAICS code 325412 for pharmaceutical and medicine manufacturing and is classified as a subcontract within the Department of Defense’s Medical Supply Chain framework. The performance location is designated as Fort Stewart, Georgia, with a response deadline of July 27, 2026. The posting date of July 19, 2026, indicates a limited eight-day window for interested parties to submit proposals, and the contract is administered through the Defense Logistics Agency’s DIBBS system under the reference number SPE2DS26T247E.
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NAICS: 325412
New
DIBBS
Oral Rehydration Salts (ORS) Powder SupplyThe contract seeks the manufacture and supply of oral rehydration salts in powder form, packaged in units of 100 packets, intended for commercial off-the-shelf medical use in oral administration. The product must meet established specifications for efficacy, safety, and packaging standards to ensure consistent quality and ease of use in clinical and humanitarian settings. Production and packaging processes must comply with applicable regulatory requirements for pharmaceutical products, with all units labeled appropriately and prepared for bulk distribution. This is a subcontract under the Department of Defense, managed by the MEDICAL SUPPLY CHAIN PHARM FSA, with performance required at APO, ZIP 96319-5000. The solicitation was posted on July 19, 2026, and responses are due by July 27, 2026. The NAICS code 325412 identifies the industrial classification as pharmaceutical and biological product manufacturing, indicating the technical scope of the required capabilities. The nature of the contract implies a focus on reliable, large-scale production to support military and allied health programs, with an emphasis on timely delivery and adherence to strict quality control protocols.
MEDICAL SUPPLY CHAIN PHARM FSA

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NAICS: 325412
New
DIBBS
Pharmaceutical Supply – Sodium Nitroprusside (50 mg/2 mL vial)The contract seeks the supply of one unit of Sodium Nitroprusside, USP, in a 2 mL vial containing 50 mg of sodium nitroprusside dihydrate, fully compliant with federal and military pharmaceutical standards. The product must meet the stringent quality and safety requirements mandated for use within the Department of Defense medical supply chain, ensuring it is suitable for deployment in clinical and field environments. The item is to be delivered to a military address in APO with ZIP code 96543-4010, indicating its intended use by U.S. military medical personnel in overseas or expeditionary operations. This is a subcontract under NAICS code 325412, which classifies it within pharmaceutical and medicine manufacturing, and was posted on July 19, 2026, with a response deadline of July 27, 2026. All submissions must align with the Department of Defense’s procurement protocols and be submitted via the DIBBS platform at the provided link. The contract does not specify any set-aside preferences and does not list a point of contact, suggesting that the procurement process is standardized and handled through established military supply channels without additional negotiation. Compliance with all regulatory requirements and timely delivery are critical to fulfilling the terms of this agreement.
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NAICS: 325412
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HYDROGEN PEROXIDE TOPIThe contract calls for the procurement of Hydrogen Peroxide Topical Solution, USP, a 3% stabilized topical antiseptic intended for external use only, with no use in the eyes or over large body areas and a maximum duration of one week. Each unit is a 473-milliliter bottle packaged as the unit of issue, and must be stored tightly closed at controlled room temperature, protected from freezing and excessive heat, with no shaking of the container. All labeling and packaging must adhere to Medical Marking Standard No. 1, superseding MIL-STD-129 for medical items, and the product must be marked with its NSN 6505001538480 and applicable NDC codes as specified by approved manufacturers including McKesson, Cardinal Health, and Medline. The item is regulated by the FDA and classified as a Type I (Code M) item with a non-extendable 24-month shelf life. As a hazardous material under FED-STD-313, suppliers must provide Safety Data Sheets (SDS) and Hazard Communication Standard (HCS) compliant labels per 29 C.F.R. 1910.1200, alongside employee training on these requirements. Packaging must meet commercial standards, utilizing sealed unit containers and suitable shipping containers to prevent damage during transit, with palletization in accordance with DLA Packaging Requirement RP001. If the material is deemed hazardous, packaging must comply with TQ Requirement IP025; for non-hazardous cases, ASTM D3951 applies unless overridden by the DLA Master List of Technical and Quality Requirements. Delivery is required FOB destination within five days of order placement, with inspection and acceptance occurring at the delivery point. The product is being procured under multiple contract line items at varying unit prices between $1.85 and $2.72 per bottle, with a total estimated value of approximately $528.62. Payment must be processed through Wide Area WorkFlow (WAWF), and the contract incorporates a full suite of FAR and DFARS clauses, including cybersecurity requirements under NIST SP 800-171, prohibitions on Chinese military company equipment, whistleblower protections, ethical restrictions on former DoD officials, and mandatory reporting of cyber incidents. The contract mandates compliance with all applicable standards and precludes use of parcel post for shipping—delivery must occur via the fastest traceable means to designated
MEDICAL SUPPLY CHAIN PHARM FSA

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NAICS: 325412
New
DIBBS
Supply of Doxycycline Hyclate Tablets (FDA-Compliant Pharmaceuticals)The contract entails the supply and delivery of 11,000 bottles of Doxycycline Hyclate Tablets, identified by NSN 6505016421190 and P/N NDC24658-0312-10, in full compliance with federal pharmaceutical regulations, current Good Manufacturing Practices, and all Department of Defense delivery protocols. The product must meet stringent quality and safety standards to ensure suitability for military and federal healthcare use, with packaging, labeling, and documentation adhering to established government specifications for pharmaceuticals. The subcontract is administered under the Defense Logistics Agency, part of the Department of Defense, and falls under NAICS code 325412 for pharmaceutical and biological product manufacturing. Performance is expected to align with federal timelines and logistics requirements, though specific delivery locations and point of contact details are not provided. The contract was posted on July 19, 2026, and can be referenced through the DIBBS system under contract number SPE2DX25D8022 and delivery order SPE2D926F7449.
Defense Logistics Agency

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NAICS: 325412
New
DIBBS
Supply of Dextrose Oral Gel (NSN 6505014253168)The contract specifies the procurement and delivery of four packages of Dextrose Oral Gel identified by NSN 6505014253168 and NDC 00574-0069-30, with full compliance required to all applicable federal pharmaceutical standards. The product must be shipped FOB Destination to a U.S. Navy vessel stationed at FPO AP 96668, ensuring the government assumes responsibility for the goods only upon arrival at the designated location. Upon delivery, the shipment is subject to official government inspection to verify adherence to quality, labeling, and regulatory requirements. The contract falls under the NAICS code 325412 for pharmaceutical preparation manufacturing and is classified as a subcontract under the Defense Logistics Agency, part of the Department of Defense. The award is linked to solicitation SPE2DX25D9900 with delivery contract SPE2DP26F7748, and was posted on July 19, 2026, indicating a future performance timeline consistent with federal procurement scheduling practices.
Defense Logistics Agency

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1 day ago

DEADLINE

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NAICS: 325412
New
DIBBS
Pharmaceutical Supply – Sulfadiazine Silver (Topical Antimicrobial)The contract entails the supply and delivery of two jars of Sulfadiazine Silver, identified by NSN 6505005607331 and NDC 43598-0210-40, a topical antimicrobial specifically used in the treatment of burn wounds. The product is to be delivered to a U.S. Navy vessel operating at sea, ensuring medical readiness for onboard personnel in remote and challenging environments. This transaction is classified as a subcontract under the NAICS code 325412, which pertains to pharmaceutical and biological product manufacturing, and is managed by the Defense Logistics Agency on behalf of the Department of Defense. The contract was posted on July 19, 2026, and is linked to the award number SPE2DX25D8022 with delivery order SPE2D926F7448, indicating it is part of a broader procurement effort to maintain critical pharmaceutical inventory for military medical needs. The place of performance and contact details are not specified, reflecting the operational nature of the delivery to a mobile naval platform.
Defense Logistics Agency

POSTED

1 day ago

DEADLINE

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NAICS: 325412
New
DIBBS
Supply of Simethicone Tablets (NSN 6505014731770)The contract obligates the procurement and delivery of two bottles of FDA-approved Aluminum, Magnesium, Simethicone Tablets identified by National Stock Number 6505014731770 and National Drug Code 00904-6700-60, ensuring full compliance with federal standards for commercial pharmaceutical products. These tablets are to be supplied under a subcontract awarded by the Defense Logistics Agency, a component of the Department of Defense, with the North American Industry Classification System code 325412 indicating pharmaceutical manufacturing as the relevant industry sector. The solicitation was posted on July 19, 2026, and the delivery must fulfill specific federal requirements governing pharmaceutical quality, packaging, and safety. The place of performance and point of contact details are not specified, but the contract is tied to the DIBBS award system under reference SPE2D926F7446. The transaction is governed by the contractual obligations of the Department of Defense and requires adherence to all applicable regulatory and logistical protocols for federal pharmaceutical supply.
Defense Logistics Agency

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NAICS: 325412
New
DIBBS
Pharmaceutical Supply of Antacid TabletsThe contract involves the supply of eight units of Aluminum, Magnesium, Simethicone Tablets, identified by NSN 6505014731770 and NDC 00904-6700-60, with all packaging and labeling required to comply with FDA regulations and include the NSN, NDC, and CAGE codes. The product is intended for pharmaceutical use and must be fully prepared and ready for immediate shipment upon delivery. This is a subcontract under the Defense Logistics Agency, part of the Department of Defense, and falls under the NAICS code 325412 for pharmaceutical and medicinal product manufacturing. The solicitation was posted on July 19, 2026, and the award is linked to contract SPE2DX25D8022 with delivery order SPE2D926F7447, indicating active procurement activity within the military logistics system.
Defense Logistics Agency

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NAICS: 325412
New
DIBBS
Supplier of MOXIFLOXACIN HYDROCHLORIDE TABLETSThe contract requires the supply of bulk MOXIFLOXACIN HYDROCHLORIDE TABLETS in a quantity of 15,000 bottles, adhering strictly to United States Pharmacopeia and federal procurement standards. The solicitation is issued under the NAICS code 325412 for pharmaceutical manufacturing and is classified as a subcontract, with the Medical Supply Chain Pharm FSA acting on behalf of the Department of Defense as the awarding agency. All delivered product must meet exacting quality and compliance criteria to ensure suitability for federal use. The place of performance is designated as FPO with a ZIP code of 96674, indicating delivery to a military post office location, and the response deadline is set for July 27, 2026. Interested suppliers must submit proposals by this date to be considered, with the opportunity to bid via the DIBBS platform using the provided link.
MEDICAL SUPPLY CHAIN PHARM FSA

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