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NAICS Code· 325412

NAICS 325412: Pharmaceutical Preparation Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing in-vivo diagnostic substances and pharmaceutical preparations (except biological) intended for internal and external consumption in dose forms, such as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions. Cross-References. Establishments primarily engaged in--Show more

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex manufacturing processes governed by cGMP standards, requiring validated equipment, rigorous quality control, and strict environmental controls to ensure product safety and efficacy.

198
Active Contracts
$15.3B
Total Obligations (12mo)
13.1K
Awarded Contracts (12mo)
342
Contractors Awarded (12mo)
1
Median Bidders per Award
-28.2%
YoY Growth

Industry Spending Overview

Federal obligations, top contractors and agencies, and related industry codes for NAICS 325412.

AI Industry Description

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex ma...

NAICS 325412 – Pharmaceutical Preparation Manufacturing encompasses the formulation, production, and packaging of finished pharmaceutical products, including sterile injectables, oral solids, topical creams, and other dosage forms intended for human or veterinary use. This sector involves complex manufacturing processes governed by cGMP standards, requiring validated equipment, rigorous quality control, and strict environmental controls to ensure product safety and efficacy. In government contracting, this NAICS supports critical public health and military readiness initiatives, with agencies procuring medications for clinical use, emergency stockpiles, and deployed medical units. The industry bridges advanced chemistry, regulatory compliance, and supply chain resilience, making it a high-stakes segment within federal healthcare and defense procurement. Top contractors in this sector include ALTITUDE TECHNOLOGIES INC., MARATHON MEDICAL CORPORATION, NANOSONICS INC, LINDE GAS & EQUIPMENT INC., and BHPE LLC, representing a mix of specialized pharmaceutical manufacturers, medical device integrators, and gas supply providers supporting sterile production environments. These firms range from mid-sized primes to niche technical service providers, indicating a competitive landscape where regulatory expertise and cold-chain logistics capabilities are as critical as manufacturing scale. The Department of Health and Human Services, Department of Veterans Affairs, and Department of Defense are the primary buyers, driving demand through hospital formularies, VA pharmacy networks, and military medical readiness programs. Procurement focuses on FDA-approved therapeutics, pandemic preparedness stockpiles, and battlefield medical supplies requiring extended shelf life and transport stability. The market is characterized by high barriers to entry due to FDA oversight and cGMP compliance, but offers consistent demand from mission-critical agencies. Opportunities exist for contractors with validated manufacturing facilities, sterile compounding capabilities, and experience in federal supply chain protocols. Recent trends show increased emphasis on domestic sourcing and resilient production networks to reduce reliance on foreign active pharmaceutical ingredients.

Top Contractors

Companies with the highest total award value under NAICS 325412, ranked by dollars won.

Ranked by total awards
CompanyTotal AwardsContracts
MCKESSON CORPORATION$11.1B1,529
MERCK SHARP & DOHME LLC$1.4B27
GLAXOSMITHKLINE$580.8M9
SANOFI PASTEUR$509.8M106
PFIZER INC.$478.1M910
ALNYLAM PHARMACEUTICALS, INC.$387.8M1
DAIICHI SANKYO, INC.$250.2M13
GOLDEN STATE MEDICAL SUPPLY, INC$198.3M247
EXELAN PHARMACEUTICALS, INC.$154.1M101
COLLEGIUM PHARMACEUTICAL, INC.$143.6M1

Top Agencies

Federal agencies directing the most contract spending toward NAICS 325412.

Department Of Veterans Affairs1,162 awards$11.1B
Department Of Health And Human Services109 awards$3.4B
Nac Federal Supply Schedule (36F797)12 awards$911.1M
DLA Troop Support17 awards$308.3M
Department Of Justice1,735 awards$158.6M
Department Of Defense9,705 awards$56.1M
262-NETWORK Contract Office 22 (36C262)14 awards$25.6M
244-NETWORK Contract Office 4 (36C244)12 awards$20.6M
Nac Pharmaceuticals (36E797)2 awards$20.4M
Network Contract Office 23 (36C263)5 awards$10.8M

Competition

How many companies historically bid on federal awards in NAICS 325412, from bidder counts reported on USAspending.

Usually Single-Bid

Half or more of reported awards drew exactly one bidder, usually a sign of incumbent-held work rather than an open field. · 213,378 reported awards

Median Bidders

1

Per reported award, all-time

Single-Bid Awards

62%

Share of reported awards with one bidder

10+ Bidder Awards

3%

Share of reported awards with 10+ bidders

Reported Awards

0

61% of 348,121 total awards

How this code compares up the NAICS hierarchy. Parent cohorts pool every code under their prefix, so they are the steadier baseline when a 6-digit sample is thin.

Industry FamilyCompetitionMedian BiddersSingle-BidBidder MixReported Awards
325412This Code
Pharmaceutical Preparation Manufacturing
Usually Single-Bid162%
213,37861% of 348,121
32541NAICS Industry
Moderate Competition434%
767,21730% of 2,563,327
3254Industry Group
Pharmaceutical and Medicine Manufacturing
Moderate Competition434%
767,21730% of 2,563,327
325Subsector
Moderate Competition336%
1,583,63836% of 4,450,321
32Sector
Manufacturing
Moderate Competition331%
3,142,44429% of 10,788,433

Bidder counts reported on past federal awards in this NAICS (USAspending). An open opportunity has no bidders yet, so this is the historical norm for similar work, not a fact about this solicitation. Not all awards report bidder counts, and fewer bidders often means incumbent-held work rather than an easier win. Federal reporting of bidder counts fell from ~96% of awards (FY2016) to ~30% (FY2018 onward); the chart shows shares of reported awards, and washed-out stretches mark years with fewer than 30 of them.

Related NAICS Codes

Industries similar to Pharmaceutical Preparation Manufacturing, by shared sector, subsector, and industry group.

Medicinal and Botanical Manufacturing

This U.S. industry comprises establishments primarily engaged in (1) manufacturing uncompounded medi...
325411Same Industry GroupHigh Similarity

In-Vitro Diagnostic Substance Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing in-vitro (i.e., not t...
325413Same Industry GroupHigh Similarity

Biological Product (except Diagnostic) Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing vaccines, toxoids, bl...
325414Same Industry GroupHigh Similarity

Petrochemical Manufacturing

This industry comprises establishments primarily engaged in (1) manufacturing acyclic (i.e., aliphat...
325110Same SubsectorMedium Similarity

Industrial Gas Manufacturing

This industry comprises establishments primarily engaged in manufacturing industrial organic and ino...
325120Same SubsectorMedium Similarity

Synthetic Dye and Pigment Manufacturing

This industry comprises establishments primarily engaged in manufacturing synthetic organic and inor...
325130Same SubsectorMedium Similarity

Other Basic Inorganic Chemical Manufacturing

This industry comprises establishments primarily engaged in manufacturing basic inorganic chemicals ...
325180Same SubsectorMedium Similarity

Ethyl Alcohol Manufacturing

This U.S. industry comprises establishments primarily engaged in manufacturing nonpotable ethyl alco...
325193Same SubsectorMedium Similarity

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NAICS 325412 FAQ

Frequently Asked Questions

NAICS code 325412 covers Pharmaceutical Preparation Manufacturing. This U.S. industry comprises establishments primarily engaged in manufacturing in-vivo diagnostic substances and pharmaceutical preparations (except biological) intended for internal and external consumption in dose forms, such as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions. Cross-References. Establishments primarily engaged in--

Recently Posted in Pharmaceutical Preparation Manufacturing

NAICS: 325412
Awarded
DIBBS
AMOXICILLIN TABLETS
Solicitation # SPE2DP-26-T-4411
Amoxicillin Tablets USP 250 mg in blister packs of three tablets per unit, identified by NDC 00093-2268-01, are procured under solicitation SPE2DP-26-T-4411 with a required delivery of five days FOB destination. The contract specifies a total quantity of two blister trays (BT), each containing three units, for a total of six units, with zero variance allowed in quantity. The product must comply with strict packaging and marking standards per Medical Marking Standard No. 1, superseding MIL-STD-129, and must be packed in sealed unit containers that protect against damage, with shipping containers suitable for commercial carrier transport at the lowest rate. Shelf life is fixed at 24 months with no extensions permitted, in accordance with Type I (Code M) requirements. The item must be labeled and marked exactly as specified, and all packaging must conform to MIL-STD-2073-1E. The supplier must be either TEVA Pharmaceuticals USA, Inc. or Cardinal Health 200, LLC, and the product must meet all technical and quality standards referenced in the DLA Master List of Technical and Quality Requirements. Inspection and acceptance occur at the destination, and delivery is to Fort Lewis, WA, with the contracting office located under the Department of Defense’s Medical Supply Chain. The solicitation was posted on August 2, 2026, with responses due by August 10, 2026, and the NAICS code is 325412 for pharmaceutical preparation manufacturing.
Defense Logistics Agency

POSTED

1 day ago

DEADLINE

N/A
View Details
NAICS: 325412
New
DIBBS
POVIDONE-IODINE TOP
Solicitation # SPE2DP-26-T-4908
This contract is for the procurement of Povidone-Iodine Topical Solution, USP, 10 percent, in 1/2 fl oz bottles. The item is supplied in packages of 50 bottles per unit of issue. It is classified as a critical application item regulated by the FDA, with a total shelf life of 36 months and a requirement that at least 31 months of shelf life remain upon delivery to the government. The agreement specifies that packaging and labeling must adhere to Medical Marking Standard 1 and DLA packaging requirements. Delivery is set as FOB Destination to San Antonio, Texas, with a required delivery timeframe of five days. The contract includes specific quality and technical requirements from the DLA Master List and mandates that shipments be made via the fastest traceable means, explicitly prohibiting the use of parcel post.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
APPLICATOR, SILVER NITR
Solicitation # SPE2DP-26-T-4903
This contract is for the procurement of silver nitrate applicators, which are prescription-only devices for topical use. Each applicator consists of a mixture of 75 percent silver nitrate and 25 percent potassium nitrate, measuring 6 inches in length. The items are issued in containers of 100 units and must be stored at room temperature in a dark, dry location away from oxidizable materials. The product is regulated by the FDA and has a non-extendable shelf life of 24 months. The order consists of one container with a delivery requirement of 20 days after receipt of order. Because the material is classified as hazardous, the supplier must provide a current Material Safety Data Sheet both to the DLA electronic mailbox and with each shipment. Packaging must comply with 49 CFR and ICAO technical regulations. The procurement is managed by the Department of Defense Medical Supply Chain Pharmacy FSA under solicitation SPE2DP-26-T-4903.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
ISONIAZID TABLETS
Solicitation # SPE2DP-26-T-4901
This contract is for the procurement of Isoniazid Tablets USP, 300 mg, with a unit of issue consisting of bottles of 100 tablets. The order specifies a quantity of two bottles under NSN 6505001326904, with a required delivery date of September 8, 2026, and a delivery window of 20 days. The product is FDA regulated and must be stored at medical controlled room temperature, featuring a non-extendable shelf life of 36 months. The agreement mandates strict adherence to DLA packaging and marking standards, including Medical Marking Standard No. 1 and MIL-STD-129. Supplies must be delivered FOB destination to the USS Somerset LPD 25. Additionally, the contract prohibits the intentional addition of mercury or mercury-containing compounds to the hardware or supplies provided.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
TOLNAFTATE POWDER
Solicitation # SPE2DP-26-T-4905
This contract is for the procurement of Tolnaftate Powder USP 1% in 45 gram bottles, identified by NSN 6505014807897. The agreement includes two line items with quantities of one and six bottles respectively, to be delivered FOB destination to the USS Tucson. The required delivery timeframe is 20 days after the order is placed, with an original required delivery date of September 9, 2026. The supplier must adhere to strict quality and packaging standards, including the DLA Master List of Technical and Quality Requirements and Medical Marking Standard No. 1. The product is classified as a Type I item with a non-extendable shelf life of 36 months. Packaging must be commercial-grade and capable of protecting the contents from damage, with specific requirements for hazardous or non-hazardous materials according to FED-STD-313 and ASTM D3951.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
SUMATRIPTAN SUCCINATE
Solicitation # SPE2DP-26-T-4909
This contract is for the procurement of Sumatriptan Succinate 25mg film coated tablets, used for the acute treatment of migraine in adults. The requirements specify a non-extendable shelf life of 24 months and strict storage conditions between 20 to 25 degrees Celsius, protected from light. The order consists of two separate purchase requests, each for a quantity of 9 units, with a required delivery date of September 8, 2026. The agreement mandates compliance with DLA packaging and marking standards, specifically MIL-STD-129 and MIL-STD-2073-1E, and requires shipment via traceable means to destinations at Fort Bliss, Texas, and Fort Hood, Texas. Delivery is set for 20 days after the order, with inspection and acceptance occurring at the destination. The contract is managed by the Department of Defense Medical Supply Chain Pharma FSA under solicitation number SPE2DP-26-T-4909.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
SODIUM CHLORIDE OPHTHA
Solicitation # SPE2DP-26-T-4900
This contract is for the procurement of five 16-ounce bottles of Sodium Chloride Ophthalmic Solution, used as an emergency buffered eyewash. The product is an FDA-regulated medical device that must adhere to USP standards and maintain a non-extendable shelf life of 36 months. Each unit must be properly sealed in commercial packaging capable of preventing damage and must be marked according to Medical Marking Standard No. 1, including the national stock number, manufacturer date, expiration or retest date, contract number, and lot number. The order is managed under solicitation SPE2DP-26-T-4900 with a delivery requirement of 20 days after order. Shipping is designated as FOB Destination to Joint Base Lewis MCCH in Washington, and must be sent via traceable means rather than parcel post. Compliance with DLA packaging requirements and the DLA Master List of Technical and Quality Requirements is mandatory, with specific adherence to ASTM D3951 for non-hazardous materials.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
TEST STRIPS AND COLOR
Solicitation # SPE2DS-26-T-402H
This contract is for the procurement of three bottles of medical test strips and color charts used to detect bilirubin, blood, glucose, ketones, leukocytes, nitrite, pH, protein, specific gravity, and urobilinogen in urine. Each bottle contains 100 strips. The items must be delivered within 20 days after the order is placed. The supplies are subject to strict quality and packaging standards, including compliance with DLA packaging requirements and Medical Marking Standard No. 1. The product has a non-extendable shelf life of 18 months, and no more than two months may have elapsed from the date of manufacture to the date of delivery to the government. All labels must clearly display the contract number, lot number, and dates of manufacture and expiration.
MEDICAL SUPPLY CHAIN MD SURG FSF

POSTED

1 day ago

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in 5 days
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NAICS: 325412
New
DIBBS
ANESTHESIA SET, EPIDURA
Solicitation # SPE2DS-26-T-401C
This solicitation from the Department of Defense Medical Supply Chain for Joint Base Charleston seeks one package of epidural anesthesia sets under NSN 6515-01-323-6531. Each package contains 10 units, with each set featuring a 20 GA catheter and a 17 GA Tuohy Schiff winged needle along with 29 total components. Delivery is required within 20 days after receipt of the order. The supplies must have a shelf life of 12 months, and no more than two months may have passed from the date of manufacture to the date of delivery to the government. Bidders are required to specify the source and part number being supplied and must adhere to DLA master technical, quality, and packaging requirements, including the removal of government identification from any non-accepted supplies.
MEDICAL SUPPLY CHAIN MD SURG FSF

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
New
DIBBS
RABIES VACCINE, VETERIN
Solicitation # SPE2DP-26-T-4904
This contract is for the procurement of IMRAB 3, a thimerosal-free, killed-virus veterinary rabies vaccine designed for three-year protection. The item is supplied by Boehringer Ingelheim Animal Health USA under part number 10391 and is issued in packages of 50 units. Strict storage requirements are mandated, requiring refrigeration between 2 and 8 degrees Celsius and a prohibition against freezing. The product has a non-extendable shelf life of 24 months and is regulated by the FDA. The order consists of one package under solicitation SPE2DP-26-T-4904, with delivery required within 84 days. All shipments must adhere to Medical Marking Standard No. 1 and DLA packaging requirements, with inspection and acceptance occurring at the destination. The contract is managed by the Department of Defense Medical Supply Chain Pharma FSA and includes specific technical and quality requirements as outlined in the DLA master list.
MEDICAL SUPPLY CHAIN PHARM FSA

POSTED

1 day ago

DEADLINE

in 5 days
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NAICS: 325412
Awarded
Federal
Solifenacin Award
Solicitation # SPE2D2-25-D-0017
This contract pertains to the award for the procurement of Solifenacin, issued under solicitation number SPE2D2-25-D-0017 by the Department of Defense's DLA Troop Support. The contract was posted on September 23, 2025, and involves the supply of Solifenacin, a pharmaceutical product, with the performance location in Hauppauge, New York. The contracting organization is based in Philadelphia, Pennsylvania. The contract does not specify a set-aside type or size, indicating it may be open or unspecified in scope. The NAICS code associated with this procurement is 325412, which relates to pharmaceutical and medicine manufacturing. Key points include the primary points of contact, Jayne Do and Catherine Gilbert, who can be reached via email or phone for further details. The contract's details are accessible through the provided link on SAM.gov, offering additional information about the award and related procurement activities. Overall, this contract signifies a significant procurement effort by the Department of Defense to secure Solifenacin, with specific logistical and administrative details managed through the designated contacts and location.
DLA Troop Support

POSTED

1 day ago

DEADLINE

N/A
View Details
NAICS: 325412
New
Federal
Intent to Sole Source Coagulation Analyzer System
Solicitation # FA860126Q0136
The Airforce Life Cycle Management Center intends to award a sole-source, firm-fixed-price contract to Werfen USA LLC for the acquisition of Automated Coagulation Analyzer Systems for the 88th Medical Center at Wright-Patterson Airforce Base. This procurement falls under NAICS code 325412 for Pharmaceutical Preparation Manufacturing. The government has determined that Werfen is the only responsible source capable of meeting the requirements, as they are the sole provider and servicer of ACL TOP analyzers in the United States. The decision to bypass full and open competition is based on the need for specific technical capabilities, including 671 nm wavelength technology and direct Sarstedt tube compatibility, to avoid costly sample re-draws and extensive laboratory information system integration. Standardizing with Werfen ensures seamless continuity and eliminates the need for technician retraining. Interested parties may submit capability statements or exceptions to the sole source intent to the designated points of contact by September 9, 2026.
FA8601 Aflcmc Pzio

POSTED

1 day ago

DEADLINE

in 5 days
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