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Johns Hopkins University Applied Physics Laboratory 11100 Johns Hopkins Road LAUREL MD 20723 USA

UEI: SLED_4698FDC81BC44770

Johns Hopkins University Applied Physics Laboratory 11100 Johns Hopkins Road LAUREL MD 20723 USA is a federal contractor, registered under UEI SLED_4698FDC81BC44770. It has been awarded $2,220,137 in federal contracts. Primary work spans Research and Development in Biotechnology (except Nanobiotechnology). Top awarding agencies include Department Of Defense.

Contact Information

Registration and classification details

Registration

UEI Code

SLED_4698FDC81BC44770

Federal Contracting Overview

Award totals, agency breakdown, NAICS distribution, and geographic footprint.

AI Capability Profile

Johns Hopkins University Applied Physics Laboratory specializes in high-level research and development focused on proving scientific and engineering concepts. Their core capabilities include executing competitive R&D contracts to validate technical specifications and explore innovative engineering g...

Key performance metrics

Award counts and award dollars by type, as prime and as subcontractor.

Awards Count

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Total Awards

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Subcontracts

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Award analytics

Awards by agency, industry, year, award type, size, and place of performance.

Awards by Agency

Department Of Defense$2.2M100%

Awards by NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)$2.2M100%

Awards by Agency Over Time

Awards by Place of Performance

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Open opportunities in Johns Hopkins University Applied Physics Laboratory 11100 Johns Hopkins Road LAUREL MD 20723 USA's top NAICS codes and agencies

BWA Identification Core & Assay DevelopmentThe BWA Identification Core and Assay Development subcontract, managed under the Department of Defense agency W6QK Acc-Apg, focuses on the creation and supply of core biological detection technology and assays for U.S. Navy EMBD IDS projects. The primary objective is to develop assays capable of identifying toxins, viruses, and bacteria with sensitivity and specificity levels that match laboratory PCR standards. To ensure accuracy, the project utilizes biological agent panels and simulants during the testing phase. The scope of work requires the delivery of a biological detection engine, specialized assay kits, and comprehensive performance data. This effort is categorized under NAICS code 541714 and is slated for performance in Gunpowder. The solicitation was posted on November 6, 2026, with a response deadline set for December 7, 2026.

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Solicitation # DARPA-PS-26-137

The Firefox program, managed by the DARPA Biological Technologies Office, is a 36-month, three-phase initiative seeking to develop a 100-channel, non-invasive brain-computer interface with 50-micron spatial and 100-microsecond temporal resolution. The program focuses on two primary technical hurdles: the creation of components for dynamic rastering and scanning of coherent optical signals to target multiple regions of interest, and the development of non-digital data processing architectures capable of handling high data rates and computational burdens. Multiple awards are anticipated, with funding ranging between 4 million and 7 million dollars per award. Awards will be issued as Other Transaction for Prototype agreements under 10 U.S.C. 4022, utilizing a milestone-based payment schedule. The selection process is multi-staged, beginning with an abstract evaluation based on technical comprehension, technical ability, and budget realism, followed by an Oral Presentation Proposal for selected candidates. Proposers must be registered in the System for Award Management and possess a Unique Entity Identifier. Key compliance requirements include adherence to ANSI laser safety limits for human tissue exposure, Cybersecurity Maturity Model Certification, and strict guidelines regarding organizational conflicts of interest and foreign influence risk assessments.

Defense Advanced Research Projects Agcy

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Predictive Tool Development for Material PropertiesThis subcontract opportunity involves the development of computational tools designed to predict material properties in support of prime contractors working on DARPA Biological Technologies Office projects. The primary objective is to create predictive models and software tools that can forecast material formulation behavior by leveraging high-performance computing, molecular modeling software, and artificial intelligence or machine learning frameworks. Managed under the Department of Defense for the Defense Advanced Research Projects Agency, the project falls under NAICS code 541715. The successful provider will be responsible for the delivery of functional predictive software tools that accurately determine material properties. Interested parties should note the response deadline of November 30, 2026.

Defense Advanced Research Projects Agcy

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Technoeconomic Analysis (TEA) and Life Cycle Assessment (LCA) ServicesThis subcontract involves providing specialized economic and environmental impact analyses for prime contractors working on projects for the DARPA Biological Technologies Office. The scope of work focuses on conducting Technoeconomic Analysis to determine cost-viability and performing Life Cycle Assessments in accordance with ISO 14040 and 14044 standards. These assessments must be executed using industry-standard software such as SimaPro or GaBi. In addition to technical analyses, the contractor is responsible for developing comprehensive commercialization strategy plans. The primary deliverables for this engagement include detailed TEA reports, LCA reports, and strategic commercialization frameworks. This effort falls under NAICS code 541620 and supports the Department of Defense.

Defense Advanced Research Projects Agcy

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Specialty Product Formulation and DemonstrationThis subcontract, titled Specialty Product Formulation and Demonstration, is issued by the Defense Advanced Research Projects Agency under the Department of Defense. The project focuses on the development and demonstration of fully formulated, defense-relevant specialty products intended for prime contractors working on Biological Technologies Office projects. A primary requirement of the contract is the use of U.S.-produced raw materials to ensure that the resulting products meet or exceed the performance standards of current military materials. The scope of work involves utilizing specialized chemical formulation, material synthesis, and performance testing facilities to deliver final products and successful performance demonstrations. Interested parties should note that the solicitation was posted on November 5, 2026, with a response deadline of November 30, 2026. The effort is categorized under NAICS code 325998.

Defense Advanced Research Projects Agcy

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Future Program: Laguna

Solicitation # DARPA-SN-27-15

Special Notice DARPA-SN-27-15, issued by the Defense Advanced Research Projects Agency Biological Technologies Office, serves as a public notification for the forthcoming Laguna program. This notice is intended for information and program planning purposes and does not constitute a formal solicitation for proposals. The program is anticipated to be a 36-month effort focused on the development and demonstration of defense-relevant specialty products formulated from U.S.-produced raw materials. These products must meet or exceed the critical performance requirements of existing military materials. Key deliverables for the program include predictive tools for material properties, life cycle assessments, technoeconomic analyses, and commercialization strategy plans. The primary point of contact for the initiative is Dr. William Mounfield. While this notice provides an overview of research interests, DARPA will not accept submissions at this time. Formal solicitation details and submission instructions will be posted on sam.gov upon release. All communications regarding this notice must remain unclassified.

Defense Advanced Research Projects Agcy

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Leveraging NAMs to understand disease triggers, discover early biomarkers and develop new classes of therapeutic strategies for Type 1 Diabetes (U01 Clinical Trial Not Allowed)The National Institutes of Health is seeking research projects to investigate the initiation and early progression of Type 1 Diabetes using human-relevant New Approach Methodologies. Utilizing human cells, tissues, organoids, and microphysiological systems, the initiative aims to identify early biomarkers and therapeutic targets to prevent significant pancreatic beta cell loss. This effort focuses on combining innovative experimental and computational approaches to uncover the cellular and molecular mechanisms driving the disease. Selected awardees will join the Human Islet Research Network to foster collaboration, share data and tools, and coordinate the use of limited human pancreatic tissues. With total program funding of 12 million dollars and an expected 12 awards, the project is scheduled to begin around November 1, 2027. The overarching goal is to accelerate the translation of research discoveries into practical preventive and treatment strategies through a harmonized, multi-laboratory effort.

National Institutes Of Health

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Cooperative Agreement for affiliated Partner with Rocky Mountain Cooperative Ecosystem Studies Unit

Solicitation # G27AS00062

The U.S. Geological Survey is seeking a partner within the Rocky Mountain Cooperative Ecosystem Studies Unit to establish a cooperative agreement for research aimed at improving Chronic Wasting Disease surveillance. The project focuses on developing a robust, automated, and reproducible analytical pipeline to standardize Real-Time Quaking Induced Conversion assay data analysis, reducing the reliance on subjective interpretation. Key deliverables include the creation of machine-learning models using LSTM, CNN-LSTM, or hybrid architectures to classify fluorescence curves, the development of an open-source application via R-Shiny or Streamlit/Python for data ingestion and visualization, cross-laboratory validation across at least three independent facilities, and a peer-reviewed publication. The total program funding is estimated at 145,220 dollars for a single award, with an anticipated period of performance from April 1, 2027, to March 31, 2032. Applications must be submitted through grants.gov by December 8, 2026, and are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget clarity. Recipients must comply with Department of the Interior general terms, geospatial data standards under the Geospatial Data Act of 2018, and federal regulations regarding financial reporting and conflict of interest. Required submission documents include a Project Abstract Summary, Biographical Sketches, and Current and Pending Support forms for all senior key personnel.

US Geological Survey

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Cooperative Agreement for affiliated Partner with Gulf Coast Cooperative Ecosystem Studies Unit

Solicitation # G27AS00064

The U.S. Geological Survey Eastern Ecological Science Center is soliciting applications for a Cooperative Agreement under the Gulf Coast Cooperative Ecosystem Studies Unit to perform bioinformatic analysis on avian microbiome metatranscriptomic datasets. The research focuses on genome assembly-based identification of viruses, prokaryotic, and eukaryotic microorganisms, with a specific emphasis on zoonotic and wildlife pathogens. Awardees will analyze shotgun metatranscriptomic data to estimate microbial diversity and abundance across various host species, tissues, and geographic regions, while developing reproducible bioinformatic workflows. Key requirements include collaborating on peer-reviewed publications and making data products publicly available through repositories like ScienceBase or the National Center for Biotechnology Information. The solicitation, numbered G27AS00064, has a total program funding ceiling of 459,000 dollars for one expected award. The anticipated period of performance runs from April 1, 2027, to March 31, 2030, with applications due via grants.gov by December 7, 2026. Proposals are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget clarity. Applicants must be registered in SAM.gov and provide specific documentation, including a Project Abstract Summary, Biographical Sketches, and Current and Pending Support forms for key personnel. All geospatial data produced must adhere to Federal Geospatial Data Committee standards and the Geospatial Data Act of 2018.

US Geological Survey

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in about 2 months

Compliant Robotic Structures EngineeringThis subcontract for Compliant Robotic Structures Engineering supports prime contractors on DARPA projects within the Department of Defense. The scope of work involves the design and integration of flexoelectric and strain-gradient materials into robotic frames or skins to facilitate adaptive movement and proprioception. Utilizing additive manufacturing and robotics prototyping labs, the contractor is responsible for delivering integrated structural components or fully compliant robotic prototypes. The opportunity was posted on November 4, 2026, with a response deadline of December 4, 2026. It is categorized under NAICS code 333996, focusing on specialized engineering and manufacturing for advanced robotic applications.

Defense Advanced Research Projects Agcy

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Morphological & Physical Compute System DevelopmentThis subcontract, titled Morphological and Physical Compute System Development, involves the creation of physical-compute device elements and morphological-compute systems to support prime contractors on projects for the Defense Advanced Research Projects Agency. The scope of work focuses on designing physical-compute elements that utilize the mechanical state of materials to perform computational functions, leveraging specialized fabrication techniques and advanced computing architecture tools. The primary deliverables for this engagement include functional physical-compute prototypes and detailed architectural models. This opportunity is categorized under NAICS code 541715 and was posted on November 4, 2026, with a response deadline of December 4, 2026.

Defense Advanced Research Projects Agcy

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Adaptive Transduction & Sensing Device DesignThis subcontract, titled Adaptive Transduction & Sensing Device Design, supports prime contractors on projects for the Defense Advanced Research Projects Agency within the Department of Defense. The scope of work involves the design and prototyping of device elements for distributed sensing and adaptive transduction, specifically utilizing flexoelectric principles. The contractor is responsible for developing elements that encode mechanical states and creating adaptive transduction systems through the use of CAD software and MEMS fabrication facilities. Key deliverables for this engagement include functional performance reports, detailed design schematics, and physical device prototypes. The project falls under NAICS code 541330, with a response deadline set for December 4, 2026.

Defense Advanced Research Projects Agcy

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Precision Metrology & Characterization ServicesThis subcontract for Precision Metrology and Characterization Services supports DARPA projects by providing high-precision measurement and validation of the electromechanical response of flexoelectric materials. The scope of work involves utilizing nano-metrology equipment and high-precision sensors to measure local mechanical states and validate strain-gradient effects for prime contractors. The selected provider must hold ISO/IEC 17025 certification to ensure technical competence and accuracy. Key deliverables include comprehensive metrology data sets, detailed validation reports, and formal measurement accuracy certifications. The opportunity was posted on November 4, 2026, with a response deadline of December 4, 2026, under NAICS code 541715.

Defense Advanced Research Projects Agcy

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Flexoelectric Materials Research & DevelopmentThe Flexoelectric Materials Research and Development subcontract, issued under the Defense Advanced Research Projects Agency within the Department of Defense, focuses on the foundational research of materials using strain-gradient-driven electromechanical responses. The project aims to explore materials and interfaces capable of discriminating or encoding local mechanical states, utilizing atomic force microscopy and advanced synthesis laboratories to achieve these goals. The successful contractor will be responsible for delivering validated design rules, detailed characterization reports, and physical material samples. This effort supports prime contractors on DARPA projects under NAICS code 541715, with a response deadline set for December 4, 2026.

Defense Advanced Research Projects Agcy

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Immunohistochemical (IHC) Analysis SupportThe Immunohistochemical (IHC) Analysis Support subcontract, issued by the NASA Shared Services Center, involves providing specialized staining and chemical analysis of sectioned tissue for prime contractors on NASA Space Biosciences projects. The scope of work requires the application of antibodies and reagents to cryo-sectioned slides and the use of fluorescence microscopes and IHC staining stations to evaluate neuronal morphology. Due to the technical nature of the work, specialized training in neuro-histology is required to deliver the final analyzed slides and digital imaging reports. This opportunity is categorized under NAICS code 541714 and is associated with a performance location in zip code 94035. The solicitation was posted on November 4, 2026, with a response deadline of November 9, 2026.

NASA Shared Services Center

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Request for Information: Flexoelectric Future

Solicitation # DARPA-SN-27-10

The Defense Advanced Research Projects Agency DARPA Multi X Office MXO issued a Request for Information RFI under solicitation number DARPA-SN-27-10 to gather data on flexoelectric materials. This effort aims to inform future research on sensing and transduction technologies that operate under strict size, weight, power, communications, and environmental constraints. The scope focuses on foundational materials, interfaces, metrology, design rules, and device elements capable of using strain-gradient-driven electromechanical responses to encode or discriminate local mechanical states. This research is intended to support future developments in distributed sensing, adaptive transduction, morphological-compute systems, and compliant robotic structures. The RFI seeks innovative insights across three technical areas: state-of-the-art materials and scale-up pathways, state-selective strain-gradient transduction device elements for distinguishing conditions like impact or fatigue, and exploratory approaches to make strain-gradient transduction a viable technology platform. Responses must be submitted by December 4, 2026, via email to [email hidden]. Submissions must follow strict formatting guidelines, including 11-point font and specific page limits for each technical area, with a maximum of ten technical pages total. As this is an RFI for program planning purposes, it does not constitute a formal solicitation for proposals, and responses are not offers for a binding contract.

Defense Advanced Research Projects Agcy

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Service request for specimen embedding and sectioning.

Solicitation # 80NSSC27948767Q

The NASA Shared Services Center is seeking custom histology research services to support a Space Biosciences Project evaluating neuronal morphology in mouse brains exposed to radiation, isolation, and simulated microgravity. The scope of work involves planning, preliminary testing, embedding, and cryo-sectioning of specific brain regions, including the substantia nigra, hippocampus, and prefrontal cortex. The contractor must provide slides with sections 15 microns thick, which are to be delivered to Principal Investigator Dr. Joshua Alwood within 90 days after receipt of order. Performance will be located at the NASA Ames Research Center. This procurement is being conducted under FAR Part 12 for commercial items and services, with the government intending to issue a sole source contract to ZYAGEN, identified as the sole provider of the required services. While the agency is currently requesting capability statements from interested organizations by November 9, 2026, to determine if a competitive procurement is feasible, it explicitly states that quotes will not be reviewed or accepted at this stage. Primary coordination for this effort is managed by Cara Craft and Will Garrett.

NASA Shared Services Center

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Specialized Bio-Research / Protocol Compliance ConsultantThis subcontract opportunity is for a Specialized Bio-Research / Protocol Compliance Consultant to support research and development projects for the United States Navy and Marine Corps Systems Command. The selected provider will conduct research involving recombinant DNA and human or animal subjects, ensuring all activities are executed according to strict research protocols. Key responsibilities include managing recombinant DNA activities within laboratory facilities and maintaining full compliance with federal, state, and local environmental laws regarding the handling of toxic materials. All work must be performed under the necessary IRB and IACUC approvals, with the final deliverables consisting of experimental data and feasibility reports. The contract is designated as a Total Small Business Set-Aside under NAICS code 541714, specifically targeting firms with fewer than 500 employees in alignment with SBIR/STTR mandates. Interested parties must submit their responses by December 2, 2026. This role is critical for prime contractors requiring specialized expertise in bio-research compliance and the technical execution of complex laboratory protocols within the Department of Defense framework.

United States Navy

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