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This Government Contract opportunity from Department Of Defense was posted on September 26, 2023. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Air Launched Loiter Munitions (ALM) Collaboration Event (CE)

Closed
ALM(CE)Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714
New
Federal
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The Department of Veterans Affairs is issuing a Sources Sought notice to identify capable vendors for the development and production of a kidney glomerular endothelial cell specific adeno-associated virus AAV vector. This project, funded by a VA ORD Merit award, aims to create a homing peptide enabled vector platform to target the glomerular endothelium to treat kidney injury and disease while reducing off target transduction. The scope of work is divided into three primary tasks: the engineering and incorporation of targeting peptides into the AAV capsid, testing vector binding and internalization in kidney tissue slices, and evaluating the specificity and efficiency of the modified vector through bioluminescence imaging and in vivo biodistribution studies. Qualified contractors must possess extensive onsite resources, including BSL 2 laboratories, specialized DNA and RNA facilities, and advanced instrumentation such as the Agilent Fragment Analyzer and various qPCR platforms. Vendors must demonstrate proven success in animal and human cell vector delivery and maintain full compliance with AAALAC and FELASA health standards. The government requires quarterly reporting, weekly videoconferences, and biannual face to face meetings. All generated data will be subject to Government Purpose Rights, and contractors must adhere to strict federal records management and information security protocols. Interested parties must submit a capability statement, relevant literature, and socio economic status details under NAICS 541714 by November 4, 2026.
Rpo East (36C24E)

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about 6 hours ago

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NAICS: 541714
New
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Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-012
The National Institute of Allergy and Infectious Diseases (NIAID) has issued solicitation RFA-AI-28-012 to establish a consortium of Translational Centers Using Microphysiological Systems for Infectious Diseases (TCMID). The primary objective is to refine and validate human tissue models using Microphysiological Systems (MPS) to a level consistent with regulatory qualifications, thereby promoting their adoption by product developers and reducing reliance on laboratory animals. This initiative aligns with NIH and FDA guidance on New Approach Methodologies (NAMs) to accelerate the development of safer medical interventions by capturing human variability and patient-specific characteristics. The program is structured around an Administrative Core, a Qualification Core, and Scientific Cores, with a heavy emphasis on technical readiness, reproducibility, and regulatory acceptance. Key deliverables include the validation of assays for specific endpoints and the submission of regulatory packages. Applicants must be domestic entities, as foreign organizations and foreign subawards are strictly prohibited. Required personnel must possess deep expertise in infectious diseases, MPS platforms, bioinformatics, and FDA submission processes. Applications are due by January 29, 2027, and must be submitted via the NIH ASSIST system or approved institutional system-to-system solutions. Evaluation is based on an overall impact score considering the project's significance, the suitability of the investigators, and the quality of the institutional environment. Mandatory application components include a Data Management and Sharing Plan and a Benchmarks and Timeline PDF not exceeding six pages. Awardees must also adhere to strict cybersecurity incident reporting guidelines, notifying HHS within 48 hours of any discovery.
National Institutes Of Health

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NAICS: 541714
New
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Immune Tolerance Network (UM1 Clinical Trial Required)
Solicitation # RFA-AI-28-005
The National Institutes of Health, under the Department of Health and Human Services, is seeking applications through solicitation RFA-AI-28-005 to continue the Immune Tolerance Network (ITN). This cooperative agreement aims to develop tolerogenic therapies for immune-mediated disorders, specifically focusing on autoimmune diseases, allergic diseases and asthma, and the immune-mediated consequences of transplantation. The network operates through four integrated functional areas: Leadership, Clinical Operations, Core Laboratory, and Bioinformatics. Its primary objectives include designing and conducting clinical trials, performing integrated mechanistic studies, and sharing research results. Eligible applicants include small businesses and other for-profit organizations, though non-domestic entities are ineligible. Applications are evaluated based on scientific and technical merit, with a primary focus on significance and the likelihood of exerting a sustained influence on the research field. Key requirements include maintaining active registrations in SAM.gov, eRA Commons, and Grants.gov, as well as adhering to strict cybersecurity incident reporting and human subject protection protocols. The project requires a minimum effort of 3.6 person months per year for the PD/PI and mandates participation in a kick-off meeting in Bethesda, Maryland, and bi-annual steering meetings. Applications must follow specific page limits for the research strategy subsections and include detailed plans for clinical trial implementation, data management, and biorepository services.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 3 months
NAICS: 541714
New
Federal
Pre-Award Synopsis Texas Shield
Solicitation # DARPA-SN-27-07
The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), intends to enter into an agreement with The University of Texas System consortium of universities for the Texas Shield Program. This integrated research initiative, identified by solicitation number DARPA-SN-27-07 and NAICS code 541714, focuses on developing autonomous and semi-autonomous medical technologies and scalable solutions for critical medical consumables. The primary goal is to support lifesaving medical care in contested, austere, and resource-limited environments. Key technical areas of focus include autonomous medical and robotic surgical systems, casualty evacuation, artificial-blood and supply innovation, AI-enabled clinical decision support, and mass-casualty science and simulation. This notice is a pre-award synopsis and is not a request for proposals or a competitive solicitation. Interested entities are invited to submit information by November 15, 2026, to TexasShieldxBTO@darpa.mil detailing their technical expertise, integrated research infrastructure, clinical-validation capabilities, and multi-institutional coordination capacity. Additionally, respondents must describe their consortium organizational structure, commercialization capabilities, facility clearance levels, and their ability to handle Controlled Unclassified Information. The government will not reimburse any costs associated with the preparation or submission of information in response to this notice.
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NAICS: 541714
New
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Q--AMPLICON SEQUENCING SERVICES
Solicitation # 140G0226Q0047
Solicitation 140G0226Q0047 is a firm-fixed-price request for a Blanket Purchase Agreement (BPA) to provide next generation amplicon sequencing services for the USGS Upper Midwest Water Science Center’s Michigan Bacteriological Research Laboratory. The scope of work includes providing all equipment, labor, travel, and materials necessary to support research on bacterial pathogens, harmful algal blooms, microbial ecology, antibiotic resistance, and microbial source tracking. Key technical requirements include the use of Illumina MiSeq or AVITI sequencing technologies and the potential for library preparation for 16S V4 amplicon sequencing. The BPA has a total not-to-exceed value of 250,000 dollars with an estimated period of performance from September 17, 2026, to September 16, 2031. The award process prioritizes non-priced factors significantly over cost, focusing on the offeror's qualifications and technical performance. Evaluation criteria include a detailed listing of on-site equipment and calibration dates, personnel experience, internal quality assurance procedures, and a technical narrative not exceeding two pages. Performance will be executed in Lansing, Michigan, with delivery terms set as FOB Destination. Administrative requirements include electronic invoicing via the Internet Payment Platform and compliance with various federal regulations, including the Buy American Act and specific security prohibitions regarding telecommunications equipment. Proposals must be submitted to the USGS OAG Denver Acquisition Branch by September 11, 2026.
Ofc Of Acquisition Grants-Denver

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5 days ago

DEADLINE

in 2 days

General Info

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Tampa, FL, 33605, USA

Set-Aside

NONE

Documents

0

No documents available

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Uniform Contract Format

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Timeline

PhaseClosed
Posted

special-notice

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → Hq Ussocom
Contacts2 people available
OfficeTAMPA, FL, 33621-5323, USA
Office AddressTAMPA, FL, 33621-5323, USA
Contacts
Ronald Reed Contracting Officer

Full Description

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Air-launched Loiter Munition (ALM) Collaboration Event (CE) 02 November 2023 Request to Attend NLT 12 October 2023 11:59 PM ET Purpose SOFWERX, in collaboration with USSOCOM Program Executive Office - Fixed Wing (PEO-FW), Stand-Off Precision Guided Munitions (SOPGM) Program, will host a series of events to demonstrate and integrate Air-launched Loiter Munition (ALM) capabilities. These engagements with Industry, Academia, and Government Labs, will help USSOCOM identify potential material solutions and investigate trade-space. USSOCOM intends to survey industry for mature, non-developmental, technology that may support rapid fielding of this capability. Background/Synopsis The SOPGM Program Office currently supports Special Operations Forces (SOF) aircrews with short range munitions that are employed directly to known targets, visually identified by the shooter aircraft before launch, and utilize Global Positioning System (GPS) or Semi-Active Laser (SAL) for terminal guidance. The dependencies for this employment method will place SOF Operators at an unacceptable risk during engagements in highly contested areas. New solutions are required to provide identification, tracking, and engagement of moving or mobile targets in a time compressed environment. SOF aircraft must be prepared to efficiently engage moving targets on the time scale it would face during any potential conflict with a well-resourced peer or near-peer adversary attempting an act of aggression. Traditional airborne moving target intelligence, surveillance, and reconnaissance (ISR) sensors currently employed by SOF will be inadequate for such a scenario due to deficiencies in survivability, speed, range, or sensor performance. Considering these capability gaps, USSOCOM is looking for ALMs to decrease the engagement time from minutes to seconds, improve targeting solutions, and increase the survivability of SOF. Objective 1) Explore potential ALM solutions with Industry, Academia, and Labs based upon an understanding of current SOCOM use cases and operational landscapes for future conflicts. Recent conflicts in Ukraine and elsewhere have demonstrated mature ground-launched loiter munition capabilities. This, combined with the emergence of Air Launched Effects (ALE), should provide a shorter path to viable and mature ALMs. 2) Investigate the trade-space, to include: a) Endurance, Range, Cruise and Max Airspeeds b) Payload Capacity c) Sensors/Seekers, Semi-Active Laser (SAL), Electro-Optical/Infrared (EO/IR), Radio Frequency (RF), Automatic Target Recognition (ATR), Automatic Target Detection (ATD) d) Command and Control (C2) Data-Link, Telemetry, Transponder, Flight Termination System e) Counter Detection f) Warhead and Fusing g) Employment from various SOCOM aircraft (ex: AC-130J, MQ-9, MQ-1, MH-60, and others) h) Aircraft Integration standards such as MIL-STD-1760/1553, Universal Armament Interface (UAI), Battle Management System (BMS), Common Launch Tube (CLT), and 14-inch lug racks. 3) Future proof the system for technology upgrades, with considerations for Model Based Systems Engineering (MBSE), Modular Open Systems Approach (MOSA), Weapons Open Systems Architecture (WOSA), and Weapons Government Reference Architecture (GRA), as well as producibility concerns. 4) Identify Risks, Issues, and Opportunities. Why You Should Participate USSOCOM seeks to enter into non-FAR or FAR-based agreements with Industry, Academic, and National Lab partners whose solutions are favorably evaluated by PEO-FW, AFSOC, and USASOC Subject Matter Experts (SMEs). As such, the follow-on Assessment Event (AE) is considered competitive and solutions will be evaluated independently of one another primarily for technical merit. This serves dually as notification of the intent to research the feasibility of an agreement under 10 U.S. Code, Section 4022 and/or Section 4022(f), and as notice of pre-solicitation activities IAW FAR 5.204. Event Timeline Phase 1 - 02 November 2023 Collaboration Event (CE): SOFWERX will host the Collaboration Event (CE) with Industry, Academic, and Laboratory partners focused on AFSOC and USASOC needs for Air-launched Loiter Munition (ALM) needs. During this event, Warfighters will interact with potential solution offerors and further communicate operational needs and desirements. Participation in this event is not mandatory, however, it is designed to provide insights to ensure potential offerors understand the problem set(s) fully and to increase the likelihood of matching their technologies with Warfighter needs. This CE is also an opportunity for attendees to meet and form partnerships that may provide a more comprehensive solution. If you do not wish to participate in the CE, you are free to submit your technology on/around 05 December for the AE. Request to attend the CE below, NLT 12 October. Tentative Agenda All times listed are in ET 8:00 - 8:20: Participants arrive at SOFWERX 8:20 - 8:25: SOFWERX Welcome 8:25 - 8:45: Stakeholder Overview & Problem Set 8:45 - 9:45: Current Limitations Breakout 9:45 - 10:00: Break 10:00 - 11:00: Ways to Overcome Limitations Breakout 11:00 - 12:00: Lunch (on your own) 12:00 - 2:30: Problem Statement Development 2:30 - 2:45: Break 2:45 - 3:45: Problem Statement Briefs 3:45 - 4:30: Voting 4:30 - 5:00: Path Forward Note: Agenda is subject to change This event will be held in person at SOFWERX. Phase 2 - 05 December 2023 to 05 January Submissions to the Assessment Event (AE) Open: Interested respondents who could potentially provide solutions that meet the needs of USSOCOM are encouraged to submit their capability for USSOCOM review. To submit your technology for potential Phase 4 attendance, please review the assessment criteria and follow the submission instructions that will be near the bottom of this webpage on/around 05 December. Phase 2a - 11 December 2023 Q&A Telecon: Interested offerors may participate in a virtual Q&A session to better understand the PM's specific technology objectives. The telecon will take place on 11 December 2023 2:00-3:00 PM ET. RSVP form will be available on/around 05 December. Phase 3 - 08 January 2023 to 18 January 2023 Downselect: USSOCOM will downselect those respondents/submissions they feel have the highest potential to satisfy their technology needs. Favorably evaluated submissions will receive an invitation to attend the AE on/around 19 January. Phase 4 - 06 February 2024 to 08 February 2024 Assessment Event (AE): During the AE, selected participants will be allotted a one-on-one session with the USSOCOM evaluation panel to pitch, demonstrate, and/or discuss their solutions. The forum will include a Q&A portion and discussions may continue outside of the event. Solution brief presentation guidelines will be outlined in the event invitation and solutions will be assessed according to the criteria in the link provided below. If the USSOCOM evaluation panel favorably evaluates a solution brief, negotiations for Phase 5 may immediately begin. Note: The event details are subject to change. This event will be held in person at SOFWERX. Phase 5 - Path Forward: Successfully negotiated awards may fall under any combination of these categories: Business to business research and development agreement as a sub-award through the SOFWERX Partnership Intermediary Agreement (PIA) (15 U.S. Code Section 3715) OTA for research or prototype projects (10 U.S. Code Sections 4021, 4022) An award under 10 U. S. Code, Section 4022 may result in the further award of a follow-on production agreement without additional competition based on successful prototype completion. The Government may make this follow-on production award based upon successful prototype criteria, which will be determined for each prototype project. Procurement for experimental purposes (10 U.S. Code Section 4023) Cooperative Research and Development Agreement (15 U.S. Code Section 3710a) Prizes for advanced technology achievements (10 U. S. Code Section 4025) and/or prize competitions (15 U.S. Code 3719) FAR-based procurement contract NOTE: Awardees may need to be compliant with NIST SP 800-171, Protecting Controlled Unclassified Information (CUI) in Non-Federal Systems and Organizations How You Can Participate Government, Industry, Academia, National Labs, and Non-Traditional Attendees Request to attend the 02 November Collaboration Event: Click Here to Request to Attend (NLT 12 October) Review Assessment Criteria: Will be Posted on/around 05 December Download the White Paper Template: Will be Posted on/around 05 December Complete the Submission Form: Will be Posted on/around 05 December Questions?? For event-related questions, please contact Bridget Stauffer, bridget.stauffer@sofwerx.org

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