This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on August 1, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Amendment # 1 - Response to questions - Acquisition of Sequencing Services

Closed

75F40125Q00266Federal

Submission Closed08/07/2025, 07:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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Federal

Specialized Thermal Data Analysis Services

NASA Shared Services Center

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Earth Science Modeling and SimulationThe Earth Science Modeling and Simulation subcontract supports prime contractors on projects for the NASA Goddard Space Flight Center. The scope of work involves performing scientific modeling, simulation, and data assimilation across several disciplines, including geodetic, geophysical, cryospheric, hydrospheric, and biospheric sciences. Key responsibilities include the development of scientific models, the execution of experiment design, and the advancement of scientific mission development. The selected provider will be responsible for delivering research reports, simulation results, and functional scientific models. This opportunity is associated with NAICS code 541715 and is based in Greenbelt, Maryland. The response deadline for this requirement is December 4, 2026.

NASA Goddard Space Flight Center

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Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) Innovative Solutions Opening

Solicitation # ARPA-H-SOL-26-160

The Advanced Research Projects Agency for Health (ARPA-H) is seeking multiple awardees under Other Transaction Agreements for the Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) program. The objective is to develop a near real-time, non-destructive, AI-enabled system capable of screening pharmaceutical products and inputs through their packaging at ports of entry and other supply-chain nodes. By integrating multi-modal sensing, signal processing, and data fusion, the system aims to augment FDA oversight by detecting contamination, adulteration, and formulation variability without opening containers. The program is structured as a 54-month effort divided into three 18-month phases, culminating in a fieldable platform with integrated visual imaging and machine-readable code documentation. Eligible respondents include universities, non-profit organizations, small businesses, and other commercial entities, provided they maintain active registration in SAM.gov and are not entities of concern under the CHIPS and Science Act of 2022. The submission process requires a mandatory Solution Summary Presentation by September 21, 2026, followed by a full proposal due by November 10, 2026. Full proposals must include a technical and management plan, a task description document, a cost proposal narrative and workbook, and a milestone payment schedule. Selection will favor technologies capable of analyzing a broad range of products and packaging, while destructive testing methods and technologies requiring the opening of samples are explicitly excluded from the scope.

Advanced Research Projects Agency For Health (arpa-H)

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HYDROSPHERE, BIOSPHERE, & GEOPHYSICS (HBG) SUPPORT SERVICES II - FINAL REQUEST FOR PROPOSAL (FRFP)

Solicitation # 80GSFC27R0015

The National Aeronautics and Space Administration Goddard Space Flight Center is soliciting proposals for the Hydrosphere, Biosphere, and Geophysics (HBG) Support Services II contract, under solicitation number 80GSFC27R0015. This small business set-aside is a hybrid Indefinite Delivery Indefinite Quantity (IDIQ) contract with a five-year effective ordering period. The contract allows for the issuance of both Cost Plus Fixed Fee (CPFF) and Firm-Fixed Price (FFP) task orders to support science research and computing activities across various laboratories, including the Cryospheric Sciences, Ocean Ecology, Hydrological Sciences, Biospheric Sciences, Geodesy and Geophysics, and the Terrestrial Information Systems Laboratory. The primary objective is to develop and apply space, field-deployed, and laboratory-based technologies to address societal issues related to water resources, ecosystems, sea level change, and the Earth's magnetic and gravity fields. The scope of work encompasses scientific modeling, simulation, data assimilation, satellite instrument performance analysis, and the planning and execution of field campaigns. Performance will occur at the Goddard Space Flight Center and the contractor's facilities, with acceptance managed by the Contracting Officer or a designated representative. Award selection will be based on a tradeoff approach, prioritizing Mission Suitability as the most important factor, followed by Cost and Past Performance. Proposals must be submitted in four volumes, including a numerically scored Mission Suitability volume and a detailed Cost volume. Additionally, the contractor must adhere to strict security requirements, including the provision of a Cyber Supply Chain Risk Management plan and compliance with NDAA Section 889 regarding telecommunications and surveillance equipment.

NASA Goddard Space Flight Center

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Engineering Support for the Asymmetric Systems

Solicitation # N0017827R3106

The Contractor will deliver qualified personnel to integrate advanced automation capabilities into current and future naval weapon systems, providing end-to-end technical and engineering support throughout the entire acquisition lifecycle. This includes material solution analysis, design, testing, evaluation, and safe fielding of innovative weapon systems, ensuring technical excellence and operational readiness across all phases. The support spans a broad range of multi-disciplinary engineering domains such as systems, software, mechanical, embedded systems, firmware, cyber, signal, aerospace, autonomous, network, robotics, and biological/chemical systems, along with critical operational functions like information technology, intelligence surveillance and reconnaissance, cybersecurity, configuration management, information assurance, and system administration. The Contractor must also offer specialized services including rapid solution development, modeling, secure operational and financial support, software development and implementation, operational advisory, field support, mission rehearsal, training, management and analysis, and information operations. This effort supports specific programs under the Engineering Support for the Asymmetric Systems Task Order, with tasking tailored to the needs of individual projects across the mentioned technical and administrative disciplines. The solicitation, issued by the Naval Surface Warfare Center Dahlgren Division under the Department of Defense, is open through July 30, 2026, with primary point of contact Kathryn Pearce at the Dahlgren, Virginia location.

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Notice of Change in Application Due Date for NHLBI NOFOs PAR-25-025 and PAR-25-026

Solicitation # NOT-HL-27-002

This notice announces updates to the key dates for two National Heart, Lung, and Blood Institute funding opportunities, PAR-25-025 and PAR-25-026. These opportunities support early phase clinical trials for therapeutics and diagnostics related to heart, lung, and blood disorders. The primary purpose of the update is to add one additional receipt date for new applications as well as resubmission and revision applications. As a result of these changes, the expiration date for both notices of funding opportunity has been extended to February 4, 2027. A new application deadline has been established for February 3, 2027, with a corresponding earliest start date of December 2027. All other terms, conditions, and requirements of the original funding opportunities remain unchanged.

National Heart, Lung, And Blood Institute

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Notice of Change in Application Due Date for PAR-25-032 "NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)"

Solicitation # NOT-HL-27-003

The National Heart, Lung, and Blood Institute has issued a notice regarding changes to the Notice of Funding Opportunity PAR-25-032 for Clinical Trial Pilot Studies. The primary purpose of this update is to extend the availability of the funding opportunity by adding an additional receipt date for new applications as well as resubmission and revision applications. As a result of these changes, the expiration date for the NOFO has been moved to March 17, 2027. All other terms, conditions, and requirements of the original solicitation remain unchanged. Applicants are reminded that all submissions must be received by 5:00 PM local time of the applicant organization.

National Heart, Lung, And Blood Institute

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Notice of NHLBI Withdrawal from Participation in PA-25-305 "NIH Research Project Grant (Parent R01 Clinical Trial Required)"

Solicitation # NOT-HL-27-001

This notice announces that the National Heart, Lung, and Blood Institute (NHLBI) will withdraw its participation from the NIH Research Project Grant PA-25-305, which requires clinical trials. This withdrawal becomes effective for all application due dates occurring after July 5, 2026. While the NHLBI is exiting this specific funding opportunity, all other participating NIH organizations and institutes remain involved. No other terms or conditions of the original notice of funding opportunity have been changed.

National Heart, Lung, And Blood Institute

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Notice of NIDCR Participation in PA-25-302, NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

Solicitation # NOT-DE-27-001

The National Institute of Dental and Craniofacial Research (NIDCR) has announced its participation in the NIH Small Research Grant Program, specifically under the Notice of Funding Opportunity PA-25-302. This program, which does not allow clinical trials, is effective for application due dates on or after February 16, 2027. The NIDCR joins a wide array of other NIH institutes and centers, including the National Cancer Institute and the National Center for Advancing Translational Sciences, in offering this funding opportunity. All submitted applications must align with the specific missions of the participating Institutes or Centers. Additionally, the Office of Data Science Strategy may provide co-funding for assigned applications. While the list of participating organizations and associated assistance listing numbers has been updated to include the NIDCR, all other terms and conditions of the original funding opportunity remain unchanged.

National Institute Of Dental And Craniofacial Research

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Director's Fellowship Research SupportThe Director's Fellowship Research Support is a subcontract opportunity with the Defense Advanced Research Projects Agency under the Department of Defense. This initiative seeks high-level academic research expertise to support prime contractors on DARPA projects, specifically focusing on advanced research in plasma physics, thermomechanical resilience, and AI/ML. Work is to be conducted using institutional or university research facilities, with expected deliverables including technical contributions, academic publications, and fellowship research outputs. Qualified candidates must hold a PhD or an equivalent advanced degree and meet all established DARPA fellowship criteria. The solicitation was posted on October 20, 2026, and requires responses by January 13, 2027. This effort falls under NAICS code 541715, emphasizing the specialized nature of the scientific research required for these defense initiatives.

Defense Advanced Research Projects Agcy

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Scalable Thermomechanical Resilience ResearchThe Scalable Thermomechanical Resilience Research subcontract, issued by the Defense Advanced Research Projects Agency under the Department of Defense, focuses on investigating fundamental mechanisms to improve the thermomechanical resilience of materials and devices. The project involves analyzing material behavior under thermal and mechanical stress through the use of stress-testing rigs, thermal imaging, and SEM/TEM characterization. The primary goal is to provide prime contractors with critical material specifications, performance reports, and resilience models. Qualified candidates must possess specialized expertise in Thermodynamics, Mechanical Engineering, or Materials Science. This opportunity was posted on October 20, 2026, with a response deadline of January 13, 2027. The work falls under NAICS code 541715, emphasizing the research and development nature of the technical requirements.

Defense Advanced Research Projects Agcy

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Plasma Dynamic Heterostructure Layer ResearchThis subcontract, titled Plasma Dynamic Heterostructure Layer Research, supports prime contractors on DARPA research projects within the Department of Defense. The scope of work involves the research and development of plasma as a dynamic heterostructure layer for electron emission. The selected party will be responsible for designing and testing these layers and analyzing emission properties utilizing spectroscopy tools, plasma generation equipment, and vacuum chambers. The project requires specialized expertise in Quantum Electronics, Materials Science, or Plasma Physics. Key deliverables include prototype plasma layer configurations, technical reports, and comprehensive experimental data. This opportunity was posted on October 20, 2026, with a response deadline of January 13, 2027, falling under NAICS code 541715.

Defense Advanced Research Projects Agcy

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1 day ago

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in 3 months

AI Contract Overview

This contract pertains to Amendment #1 for the acquisition of sequencing services, issued under solicitation number 75F40125Q00266 by the FDA Office of Acquisition Grant Services, part of the Department of Health and Human Services. The solicitation was posted on August 1, 2025, with a response deadline set for August 7, 2025, at 7:00 PM. The contract is designated as a combined type and is set aside exclusively for small businesses under the SBA's Total Small Business Set-Aside program, in accordance with FAR 19.5. The NAICS code associated with this contract is 541715, which covers research and development in the physical, engineering, and life sciences. The contract's performance location is in Silver Spring, Maryland, while the office managing the contract is based in Beltsville, Maryland. The primary point of contact for inquiries is Hilda Aryeh, reachable via email at hilda.aryeh@fda.hhs.gov. Further details and updates regarding this contract can be accessed through the provided link on SAM.gov.