This Combined Synopsis/Solicitation opportunity from Department Of Veterans Affairs was posted on July 28, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
AN11--Degenerative cervical myelopathy (DCM) multi-omics services
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
Active Opportunities Like This One
AI Contract Overview
This solicitation, numbered 36C24E26Q0072, is a 100% small business set-aside under FAR 19.5 for multi-omics services to support research on degenerative cervical myelopathy (DCM) at the VA Pittsburgh Healthcare System. The requirement is for comprehensive, end-to-end processing and analysis of blood samples across three omics platforms: transcriptomics from PAXgene-stabilized whole blood, DIA-based quantitative proteomics from BD P100 plasma samples, and untargeted metabolomics from heparin plasma samples. The contractor must perform all sample handling, extraction, library preparation, sequencing, data acquisition, and bioinformatics analysis under a single chain of custody to ensure data integrity and minimize batch effects. Integration of the three omics datasets through pairwise comparisons, PLS-DA modeling, and correlation heatmaps is mandatory, and the final deliverables must include normalized data and secure cloud-based access for the government to generate custom visualizations. The contract is firm-fixed price with a 12-month performance period, and the work must be conducted entirely at the contractor’s facility. The contractor is responsible for arranging overnight shipping with special containment for all sample transfers to and from VA, including sample receipt, inspection, and storage, for which separate handling and setup fees are included. A one-time setup fee covers initial optimization, and shipping is itemized as a single line item. Proposals must include a detailed price list in the specified format, along with technical capabilities demonstrating expertise across all three omics platforms and bioinformatics integration. Evaluation will be based primarily on technical capability, followed by past performance (with lack of government experience rated neutrally), and then price, using a trade-off approach under FAR 13 simplified procedures. All submissions must be emailed to millicent.covert@va.gov by July 31, 2024, with the solicitation number in the subject line. The contractor must be a small business certified under NAICS 541380, with no more than $19 million in average annual receipts, and must comply with all incorporated FAR clauses including representations, certifications, evaluation criteria, and protest procedures without requiring access to VA systems or security clearance.
General Info
Agency
NAICS
Place of Performance
PASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
AMENDMENT FOR SOLICITATION 36C24E26Q0072 This solicitation is being amended to provide Question and Answers to all offerers/bidders.
QUESTION and ANSWERS Q1: What sequencing depth (Gb) or number of reads per sample (M) is required for the RNA-seq component? If there is no specific target, may we recommend one? A1: 6Gb, 150 million reads
Q2: What volume of plasma and whole blood will be provided per sample type? Additionally, will 40 separate samples be aliquoted for each project (i.e., dedicated plasma tubes for proteomics and for metabolomics), or will the same plasma sample be sent for both and need to be split at the facility? A2: Blood will be collected in specialized tubes (one tube is specialized for proteomics and one for metabolomics) they cannot be collected as one, and then later separated. Each subject will be given three tubes each: PAXgene blood tube will be mailed intact (zero processing), metabolomics blood sample will be centrifuged to collect plasma and placed into its dedicated Eppendorf tube and metabolomics blood sample will be centrifuged to collect plasma and placed into its dedicated Eppendorf tube. There will be 40 subjects for a total of 120 tubes (40 intact blood tubes for RNA, 40 metabolomics plasma samples, and 40 proteomics samples).
Q3: The pricing table (Item 0002) specifies DIA-based LC-MS/MS proteomics, but the Scope/Task 2 narrative specifies "Olink proteomics analysis." These are different technologies (untargeted mass spec vs. targeted antibody-based panels) requiring different vendor capabilities and pricing. Please confirm which platform is required DIA-MS, Olink, or both. If Olink is required, please specify the panel (e.g., Olink Explore HT, Target 96 Inflammation, etc.). A3: Thank you for pointing out the discrepancy. DIA-base proteomics is the platform required.
Extension for offers is not granted. Submission deadline remains as no later than Friday, July 31, 2026, at 11:59AM Eastern Time.
IMPORTANT: complete all instructions as noted in Instructions to Offeror within original solicitation. Additionally, please complete Blocks 15A 15C AMENDMENT OF SOLICITATION document. Incomplete submissions will be considered non-responsive. All offeror quotes for this solicitation must be received electronically through email no later than Friday, July 31, 2026, at 11:59AM Eastern Time. Offers shall be sent by email to Millicent Covert at millicent.covert@va.gov. Reference solicitation number 36C24E26Q0072 within subject line of the email. Any quotes received after the prescribed date/time shall be considered non-responsive and will not be considered for award.
More opportunities from Department Of Veterans Affairs → Rpo East (36C24E)
Same awarding agency
Find Active Opportunities Like This
Get AI-powered intelligence on the opportunities still open
Every page of the solicitation package shredded into a compliance breakdown
AI-powered matching based on your capabilities and past performance
Competitor and incumbent history on the requirement
Automated alerts on amendments, Q&A deadlines, and award
Join 650+ contractors already using CLEATUS