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AAV Vector Characterization and Quantification Services

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract opportunity is for AAV Vector Characterization and Quantification Services supporting biotechnology projects at the VA Harry S Truman Memorial Veterans Hospital under the Department of Veterans Affairs. The selected provider will deliver high-precision analytical testing to verify the purity and integrity of AAV vectors for prime contractors. Key technical requirements include performing fragment analysis of viral genomes and quantitative PCR for vector genome titration, utilizing Agilent Fragment Analyzers and qPCR platforms. The contractor is expected to adhere to GLP standards and provide formal Certificates of Analysis and quantification reports. The work will be performed in Columbia, Missouri, under NAICS code 541380. Interested parties must submit their responses by November 4, 2026.

General Info

AAV vector characterization and quantification services for VA hospital projects in Columbia, Missouri.

NAICS

541380 - Testing Laboratories and Services

Place of Performance

Columbia, PA, 65201, USA

Set-Aside

NONE

Documents

This scope was carved out of 36C24E27Q0009.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

AJ12--Development/Production - Kidney GEC-Specific AAV Vector

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Organization & Contact Information

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AgencyDepartment Of Veterans Affairs → Rpo East (36C24E)
ContactsNo contacts available
OfficeN/A
Office AddressN/A
ContactsNo contact information available

Full Description

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Provides high-precision analytical testing to verify AAV vector purity and integrity for prime contractors on VA Harry S Truman Memorial Veterans Hospital biotechnology projects. Performs fragment analysis of viral genomes and quantitative PCR (qPCR) for vector genome titration using Agilent Fragment Analyzers and qPCR platforms. GLP standards preferred. Delivers Certificates of Analysis (CoA) and quantification reports.

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More opportunities from Department Of Veterans Affairs → Rpo East (36C24E)

Same awarding agency

NAICS: 541714
New
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AJ12--Development/Production - Kidney GEC-Specific AAV Vector
Solicitation # 36C24E27Q0009
The Department of Veterans Affairs is issuing a Sources Sought notice to identify capable vendors for the development and production of a kidney glomerular endothelial cell specific adeno-associated virus AAV vector. This project, funded by a VA ORD Merit award, aims to create a homing peptide enabled vector platform to target the glomerular endothelium to treat kidney injury and disease while reducing off target transduction. The scope of work is divided into three primary tasks: the engineering and incorporation of targeting peptides into the AAV capsid, testing vector binding and internalization in kidney tissue slices, and evaluating the specificity and efficiency of the modified vector through bioluminescence imaging and in vivo biodistribution studies. Qualified contractors must possess extensive onsite resources, including BSL 2 laboratories, specialized DNA and RNA facilities, and advanced instrumentation such as the Agilent Fragment Analyzer and various qPCR platforms. Vendors must demonstrate proven success in animal and human cell vector delivery and maintain full compliance with AAALAC and FELASA health standards. The government requires quarterly reporting, weekly videoconferences, and biannual face to face meetings. All generated data will be subject to Government Purpose Rights, and contractors must adhere to strict federal records management and information security protocols. Interested parties must submit a capability statement, relevant literature, and socio economic status details under NAICS 541714 by November 4, 2026.
Research and Development in Biotechnology (except Nanobiotechnology)

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