This Government Contract opportunity from Department Of Defense was posted on April 14, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Antibacterial Nanoparticles Therapeutic (ANT) Study

Closed

PANDHA-26-P-0000_036893Federal

Submission Closed04/28/2026, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541713

Federal

Theoretical/Applied Research ScientistThis subcontract for a Theoretical/Applied Research Scientist supports the Defense Advanced Research Projects Agency within the Department of Defense. The role focuses on conducting high-risk, high-reward research to secure fundamental scientific breakthroughs for prime contractors. Key responsibilities include investigating innovative approaches to drive revolutionary advances through the use of specialized simulation software and high-performance computing. The contractor is required to deliver theoretical models, validated experimental data, and scientific papers while maintaining compliance with NIST SP 800-171 standards for the protection of controlled unclassified information. This opportunity falls under NAICS code 541713 and has a response deadline of June 1, 2027.

Defense Advanced Research Projects Agcy

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Scalable Platform for Enterprise Engineering and Deployment towards Mathematics for the Discovery of Algorithms and Architectures (SPEED DIAL)

Solicitation # DPA26TZ05-DV003

Defense Advanced Research Projects Agency

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Natural Language Processing for Aviation Audio CommunicationsThe NASA SBIR/STTR Program is seeking a subcontractor to design and demonstrate the feasibility of utilizing speech-to-text and natural language processing to identify errors within controller-pilot communications. The primary objective of this effort is to implement transcription validation and error classification to improve the safety and accuracy of aviation audio communications. This project is designated as a Total Small Business Set-Aside under NAICS code 541713 and is managed by the National Aeronautics and Space Administration. Performance for this contract is centered at Moffett Field, California, with the official posting date listed as August 20, 2026.

NASA SBIR/STTR Program

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USDA SBIR/STTR Topic 8.1 — Forests and Related Resources

Solicitation # USDA-NIFA-TOPIC-8.1

The USDA SBIR/STTR Topic 8.1 solicitation, managed by the National Institute of Food and Agriculture, seeks innovative technologies to enhance the health, productivity, and sustainability of national forests and grasslands. The program prioritizes the development of environmentally sound approaches to increase forest productivity, improve resource sustainability, and create value-added materials from woody resources. Specific areas of interest include sustainable bioenergy, biofuels derived from woody biomass, the impact of climate change on forest health, and the application of nanotechnology in wood-based products. Over a ten-year horizon, the program aims to increase the utilization of woody resources for high-value products and foster forest ecosystems that are more resilient to wildfires, pathogens, and climate-related disturbances. Key goals include improving the economic and environmental methods of sustainable harvesting and enhancing the growth and yield of forest species for more efficient land use. This opportunity is a total small business set-aside restricted to entities with fewer than 500 employees.

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DEADLINE

Nuclear Technologies Development and Integration SupportThe National Nuclear Security Administration within the Department of Energy has issued a forecast for Nuclear Technologies Development and Integration Support. This requirement falls under NAICS code 541713 and is slated for performance in Maryland. The opportunity was posted on August 10, 2026, and is categorized as a forecast with a set-aside description of other. Chelsea Murphy, the Small Business Program Manager, serves as the primary point of contact for this initiative.

National Nuclear Security Administration

POSTED

DEADLINE

STATE OF THE ART (SOTA) MICROELECTRONICS (ME) ADOPTION BROAD AGENCY ANNOUNCEMENT (BAA) FULL TEXT GENERAL ANNOUNCEMENT

Solicitation # 26S1358

The U.S. Department of the Air Force, through SAF/AQC, is issuing a Broad Agency Announcement (BAA) numbered 26-S-1358 to advance the adoption of state-of-the-art microelectronics across national security missions. This BAA does not solicit proposals directly but serves as an umbrella framework for future Topic Calls published on SAM.gov and the Classified IC-ARC, which will define specific technical requirements, submission deadlines, and evaluation criteria. The initiative focuses on accelerating the development and integration of trusted, assured microelectronics technologies, particularly those leveraging Intel 18A process nodes and advanced packaging via Secure Enclave, to ensure enduring technological superiority. Five key mission areas are highlighted: advanced secure microelectronics design and production; next-generation assembly, packaging, and test; novel microelectronics for disruptive capabilities; advanced test, validation, and mission qualification; and building an accessible, affordable, and sustainable domestic microelectronics ecosystem. Topics range from AI/ML architectures and radiation-hardened designs to chiplet-based systems, secure test methodologies, edge computing, RF electronics, PNT resilience, digital twins, and open-standard chiplet libraries. Proposals or White Papers may only be submitted in response to individual Topic Calls, which may be either closed (with fixed deadlines) or open (accepting submissions continuously during a defined window), and may follow one-step or two-step processes. Awards, if made, will take the form of procurement contracts or Other Transaction Agreements (OTAs) for prototyping, follow-on production, or experimental purposes, with eligibility open to small businesses, traditional and non-traditional defense contractors, and research institutions. OTA awards require resource-sharing commitments and participation by nontraditional contractors, small businesses, or third-party funding. Proposals must not include classified information unless explicitly directed by a classified Topic Call, which may require SECRET or higher clearances and approved secure facilities. Data rights are anticipated to include Government Purpose Rights for technical data and software, with specific terms negotiated per call. All submissions must reference the BAA number 26-S-1358 and be aligned with the specified Areas of Interest in each Topic Call. Interested parties must actively monitor SAM.gov and IC-ARC for updates, as Topic Calls may be issued throughout the BAA’s open period—initially one year, extendable annually—and any associated costs for proposal development are considered indirect, not chargeable to resulting contracts.

Department Of The Air Force

POSTED

DEADLINE

ERIS Shopping Notice: High Duty Cycle High Energy Lasers (HEL) for SWaP-Constrained Systems

Solicitation # DARPA-SN-26-82

The Defense Advanced Research Projects Agency Strategic Technologies Office is conducting an active search for innovative, awardable solutions for moderate power high energy lasers ranging from 100W to 20kW. These solutions must be designed for size, weight, and power constrained systems, such as Collaborative Combat Aircraft, unmanned aerial vehicles, and armored personnel carriers. The primary technical objective is to maximize the duty cycle to allow for successive firing over long durations, specifically by overcoming heat exhaust and cooling challenges to maintain beam coherence and steady state operation. Required deliverables include engineering designs for novel cooling approaches, scalable system architectures, and technical documentation regarding wavelength flexibility and phase control for beam tuning. This shopping notice, identified as DARPA-SN-26-82, is open from June 4, 2026, to November 30, 2026. Submissions are reviewed on a rolling basis, and the government may make awards prior to the closing date. Interested parties must submit video solutions through the DARPAConnect ERIS Portal during the designated monthly collection periods and provide email notification to the Marketplace Coordinator. Evaluation is based on the proposer's understanding of the current state of the art, the technical leap provided by the innovation, the team's combined expertise in laser technology, and the potential impact on both defense and commercial applications.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Non-Profit Research Institution Partner

National Science Foundation

POSTED

DEADLINE

NSF 26-510 | Augmented Virtual and Mixed Reality (AV/VR/MR) — Differentiated Hardware Technologies for AR/VR/MR

Solicitation # nsf-seedfund-AV-AV1_STTR

The National Science Foundation is seeking proposals under solicitation nsf-seedfund-AV-AV1_STTR for the development of innovative and differentiated hardware and software within the Augmented, Virtual, and Mixed Reality sectors. This initiative targets early-stage entrepreneurs and startups aiming to translate research-based insights into scalable, commercial applications. Key focus areas include the integration of AI for education, workforce development, health and wellbeing, and the creation of platforms for virtual collaboration and experiential learning. This opportunity is a total small business set-aside, specifically mandated for SBIR/STTR participants with fewer than 500 employees. The primary objective is to support the creation of novel technologies that enable shared experiences and provide tools for upskilling an aging workforce or improving general wellness. Interested parties can find further details through the National Science Foundation seed fund portal.

National Science Foundation

POSTED

DEADLINE

NSF 26-510 | Nanotechnology — Nanomanufacturing

Solicitation # nsf-seedfund-N-N1_STTR

The National Science Foundation has issued solicitation nsf-seedfund-N-N1_STTR for the Nanotechnology Nanomanufacturing subtopic, posted on May 22, 2026. This initiative focuses on the development and manipulation of functional materials, devices, and systems with novel properties achieved by controlling matter at a submicroscopic scale, ranging from a fraction of a nanometer up to 100 nanometers. The scope includes the creation of innovative hierarchical nanostructures, nanolayered structures, nanowires, nanotubes, quantum dots, nanoparticles, nanofibers, and various nanomaterials, biomaterials, and composite structures. This opportunity is designated as a total small business set-aside under the SBIR/STTR mandate, limiting eligibility to organizations with fewer than 500 employees. The program aims to advance the creation of advanced materials and systems through precise control of matter at the nanoscale to achieve unique functional properties.

National Science Foundation

POSTED

DEADLINE

NSF 26-510 | Nanotechnology

Solicitation # nsf-seedfund-N_SBIR

The National Science Foundation has issued solicitation nsf-seedfund-N_SBIR for the Nanotechnology topic, focusing on the development and manipulation of functional materials, devices, and systems with novel properties controlled at a submicroscopic scale. This initiative supports research into hierarchical nanostructures, nanolayered structures, nanowires, nanotubes, quantum dots, nanoparticles, nanofibers, and various nanomaterials, biomaterials, and their composite structures. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricted to organizations with fewer than 500 employees. Posted on May 22, 2026, the solicitation is managed by the National Science Foundation and aims to foster innovation in materials and systems operating from a fraction of a nanometer up to approximately 100 nanometers.

National Science Foundation

POSTED

DEADLINE

NSF 26-510 | Nanotechnology — Nanomanufacturing

Solicitation # nsf-seedfund-N-N1_SBIR

The National Science Foundation is issuing solicitation nsf-seedfund-N-N1_SBIR under the Nanotechnology topic, specifically focusing on Nanomanufacturing. This initiative supports the development of functional materials, devices, and systems created through the precise control of matter at a submicroscopic scale, ranging from a fraction of a nanometer up to 100 nanometers. Eligible projects include the creation of innovative hierarchical nanostructures, nanowires, nanotubes, quantum dots, nanoparticles, nanofibers, and various nanomaterials or biomaterials and their composite structures. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to organizations with fewer than 500 employees. The solicitation was posted on May 22, 2026, and is managed by the National Science Foundation to foster innovation in the manipulation of matter for advanced technological applications.

National Science Foundation

POSTED

4 months ago

DEADLINE

N/A

General Info

Agency

Department Of Defense → Army Medical Resources Acq ActivityView Agency

NAICS

541713 - Research and Development in NanotechnologyView NAICS

Place of Performance

Silver Spring, MD, 20910, USA

Set-Aside

NONE

Documents

(2)

RFI Antibacterial Nanoparticles Therapeutic Study PANDHA-26-P-0000

PDF•rfi

B01.+Notice+of+Intent+to+Sole+Source+PANDHA-26-P-0000+036893.pdf

PDF

AI Contract Breakdown

Uniform Contract Format

Timeline

1 update

PhaseClosed

PostedMar 18

Sources Sought

Amendment 1Apr 14

Contract was updated

Response DeadlineApr 28

Deadline has passed

Submission Closed

04/28/2026, 06:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Defense → Army Medical Resources Acq Activity

Contacts2 people available

OfficeFORT DETRICK, MD, 21702, USA

Organization / Agency

Department Of Defense → Army Medical Resources Acq Activity

View Agency Profile

Office AddressFORT DETRICK, MD, 21702, USA

Contacts

Linda Hinson

contact@example.gov

Sharew Hailu

contact@example.gov

Full Description

The University of Notre Dame will conduct a study to test innovative antibacterial nanoparticles with phage-mimicking properties (PhANPs) against combat relevant multi-drug resistant (MDR) strains of Pseudomonas (P.) aeruginosa, bacterial pathogen to cause hard to treat and even deadly infections in service members after battlefield injuries. There is a need to bring novel therapeutics to the military health care to treat MDR P. aeruginosa. The collaborative partner of this study is the University of Notre Dame, the patent owner of a unique technology (phage-mimicking nanoparticles) that provides life-saving therapeutics for service members and civilians. This technology was awarded a patent in 2024 - US-12161725-B2. Government anticipates that the collaborative efforts will contribute to Food and Drug Administration (FDA) approval of this innovative therapy, leading to reduced morbidity and mortality rates, enhanced operational readiness, advanced combat medicine, and substantial contributions to broader biosecurity initiatives and civilian health improvements.