Biopharmaceutical Automated Fill Machine Isolator

Wilson Community College is soliciting proposals for the design, fabrication, and installation of an Automated Fill Machine Isolator unit for the Biomanufacturing Education and Skills Training (BEST) Center of Eastern North Carolina. The system will be integrated into simulated cleanrooms to provide a capstone training experience for students, focusing on manual aseptic processing and operator skill development rather than high-throughput production. The project encompasses multiple phases, including engineering and design, fabrication, Factory Acceptance Testing, onsite installation, commissioning, and final acceptance. While full GMP validation is not required, the equipment must meet OSHA standards and carry appropriate safety certifications from organizations such as ASME, UL, NEMA, or the American Gas Association. The contract is expected to be completed within one year of the effective date, with onsite installation anticipated after August 11, 2027. Payment is structured around milestone deliverables, with final payment contingent upon written acceptance by the BEST Center following successful inspection and training. Vendors must provide a comprehensive technical proposal, pricing, and certifications of financial condition, along with at least three customer references. The state also maintains an option for a maintenance agreement featuring two preventive safety inspections per year. Proposals are due by November 10, 2026, and will be evaluated based on a narrative consensus of strengths and weaknesses.