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This Government Contract opportunity from Department Of Health And Human Services was posted on April 24, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Calcium Imaging and Functional Assay Services

Closed
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541612
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DEADLINE

in 12 days
NAICS: 541612
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Solicitation # 2027-RFP-394
The City of New Haven, Department of Human Resources, is seeking a professional consultant under solicitation 2027-RFP-394 to develop, validate, administer, and score promotional examinations for the New Haven Fire Department. The project focuses on identifying the most qualified candidates for the positions of Director of Training, Drillmaster, and Assistant Drillmaster, utilizing a rule of three ranks merit system. The selected consultant must ensure all processes adhere to Federal EEOC guidelines, the Federal Uniform Guidelines, and the Principles for the Validation and Use of Personnel Selection Procedures, while remaining cost-effective and legally defensible. Key deliverables include a job analysis to identify KSAOs within four weeks, the administration of a written exam within nine weeks, and a technical validation report provided three weeks after exam completion. Proposals must be submitted via the OpenGov portal by October 6, 2026, and must be divided into a technical proposal and a separate price proposal. The pricing must include a total lump-sum fee and an itemized breakdown of costs per position and per candidate. Evaluation will be based on a weighted scoring system, with a significant emphasis on legal defensibility, diversity of assessors, and commitment to the 80 percent rule for adverse impact analysis. The contract requires strict adherence to non-discrimination laws, including Executive Orders 11246 and 11375, and mandates that the contractor maintain specific insurance coverage, including a minimum AM Best rating of A-minus. Payment is processed through an e-invoice portal under a no purchase order, no payment policy.
Human Resources

POSTED

2 days ago

DEADLINE

in 24 days

AI Contract Overview

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The contract calls for the execution of calcium ion burst dynamics analysis using the FLIPR Tetra system to evaluate both acute and chronic impacts of a small molecule drug on three-dimensional brain organoids, focusing on real-time functional responses tied to neuronal activity. The work requires precise, high-throughput fluorescence imaging to capture dynamic calcium signaling patterns, enabling the assessment of how the compound alters cellular communication and network behavior over time in a physiologically relevant neural model. This effort is critical for understanding potential neurotoxic or neuromodulatory effects during early-stage drug development. The contract is classified as a subcontract under NAICS code 541612, issued by the FDA Office of Acquisition and Grant Services within the Department of Health and Human Services. It was posted on April 24, 2026, with a response deadline of May 4, 2026, at 6:00 PM. No set-aside provisions are specified, and no point of contact or detailed place of performance has been provided beyond the general agency affiliation. Interested parties must submit proposals prior to the deadline to be considered for this specialized service opportunity focused on advanced neuropharmacological screening.

General Info

Contract for calcium ion analysis in brain organoids using FLIPR Tetra to assess drug effects on neuronal activity.

Agency

Department Of Health And Human Services → FDA Office Of Acq Grant SvcsView Agency

NAICS

541612 - Human Resources Consulting ServicesView NAICS

Place of Performance

MD, USA

Set-Aside

NONE

Documents

This scope was carved out of NCTR-2026-134171.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

CNS Organoid Neuropharmacological Analysis

AI Contract Breakdown

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Timeline

PhaseClosed
Posted

subcontract

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → FDA Office Of Acq Grant Svcs
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → FDA Office Of Acq Grant Svcs
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

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Perform Ca²⁺ burst dynamics analysis using FLIPR Tetra® to assess acute and chronic effects of a small molecule drug on 3D brain organoids.

More opportunities from Department Of Health And Human Services → FDA Office Of Acq Grant Svcs

Same awarding agency

NAICS: 541714
New
Federal
Human Hindbrain Organoid Functional Assay Services.
Solicitation # RFQ_CDR-2026-135968
The U.S. Food and Drug Administration, through the Center for Drug Evaluation and Research, intends to award a sole-source, firm-fixed-price purchase order to OrganoTherapeutics SARL for human iPSC-derived hindbrain organoid functional assay services. This acquisition, conducted under FAR Part 12 as a commercial service, aims to support in vitro research on drug-induced effects on respiratory-relevant neural circuits. The scope of work includes the provision of human hindbrain organoids and associated culture materials, with twelve scheduled deliveries to the FDA White Oak Campus in Silver Spring, Maryland. The first delivery will consist of 96 organoids, followed by eleven subsequent deliveries of 48 organoids each. The contractor will perform functional characterization at its own laboratory using three-dimensional multi-electrode array technology to assess electrophysiological responses to FDA-identified drug and reversal-agent combinations. Key deliverables include the raw and analyzed data, analysis files, and comprehensive study reports. The anticipated period of performance is 18 months from the date of award. Award will be based on best value, with technical capability and past performance weighted more heavily than price. All invoicing must be processed electronically through the U.S. Department of Treasury's Invoice Processing Platform.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

1 day ago

DEADLINE

in 5 days
View Details

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