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Codon-Optimized Gene Construct Design

Active

Federal

Response Deadline08/24/2026, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract, issued by the NIH NCI under the Department of Health and Human Services, involves the design and generation of a codon-optimized gene expression cassette. The project specifically focuses on encoding the mouse tumor antigen gp70 fused with the invariant chain (Ii), ensuring compatibility with MVA and ChAdOx-1 viral vector systems for expression in mouse cells. The opportunity was posted on August 17, 2026, with a response deadline of August 24, 2026. The work is designated under NAICS code 541715 and is set to be performed in Oxford, OX3 7DQ.

General Info

NIH NCI subcontract for codon-optimized gp70-Ii gene expression cassettes in Oxford, UK.

Agency

Department Of Health And Human Services → NIH NciView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Oxford, GB-OXF, OX3 7DQ, GBR

Set-Aside

NONE

Documents

This scope was carved out of 75N98026Q00996.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Sole Source - Production of ChAdOx-1 and MVA expressing mouse gp70

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Timeline

PostedAug 17

subcontract

Response DeadlineAug 24

Submission deadline

Response Deadline

08/24/2026, 06:00:00 PM UTCin 6 days

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → NIH Nci

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → NIH Nci

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

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Design and generate a codon-optimized gene expression cassette encoding mouse tumor antigen gp70 fused with invariant chain (Ii), compatible with ChAdOx-1 and MVA viral vector systems for mouse cell expression.

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