Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)

The National Human Genome Research Institute, under the National Institutes of Health, is soliciting applications for the Computational Modeling and Analysis of the Impact of Genomic Variation on Function initiative. This opportunity, identified by solicitation number RFA-HG-27-010, seeks to establish centers that will develop, apply, and test predictive models and perform integrative analyses to understand how genomic variation affects genome function. Clinical trials are not permitted under this specific funding opportunity. Selected centers will join the Impact of Genomic Variation on Function Consortium, where they will collaborate to ensure resources are accessible to a broad user base. Members are expected to work with other consortium components to optimize experimental design, provide specialized analytical expertise, and execute shared analysis strategies to achieve overall consortium goals. Applications must be submitted by the response deadline of December 15, 2026.