Confocal Super Resolution Microscope

The contract seeks the procurement of a Confocal Super Resolution Microscope (SRM) for Brookhaven National Laboratory under solicitation number BSA477108, with a response deadline of July 20, 2026. The instrument must deliver true confocal point scanning with a tunable white light laser excitation source covering the visible spectrum, enabling simultaneous multi-line operation with independent intensity control and microsecond-scale switching between excitation regimes. It must support broadband spectral detection from approximately 400 to 850 nm with multiple independently configurable detection channels and include functional capabilities such as fluorescence lifetime imaging (FLIM) and fluorescence correlation spectroscopy (FCS), along with analytical tools for functional parameter mapping and Förster resonance energy transfer (FRET). Super-resolution performance must encompass both 2D and 3D STED nanoscopy across the visible spectrum, achieving approximately 30 nm lateral resolution. The system must operate within a unified software environment that supports automated calibration, lifetime fitting, super-resolution reconstruction, and compatibility with external analysis platforms. The contractor is responsible for the complete lifecycle of the instrument, including engineering, manufacturing, assembly, testing, delivery, installation, commissioning, and training, with a projected delivery date 36 weeks after contract award. Key milestones include submission of a Program Plan by the second week, Preliminary and Final Technical Designs by the fourth and fifth weeks, and Factory Acceptance Testing by the 30th week, followed by final acceptance testing and commissioning at BNL by the 36th week. The procurement is structured as a Firm Fixed Price contract under NAICS code 334516 with no set-aside provisions. All offerors must be registered in the System for Award Management (SAM) with a Unique Entity ID, and foreign vendors must complete AMS Form 050 instead. Required documentation includes a signed Quotation Pricing Sheet, completed representations and certifications, vendor ACH and W-9/W-8 forms, technical descriptions with illustrations, proof of ISO 9001 certification or equivalent quality system, references for at least three comparable electron microscope deliveries, and a summary of a U.S.-based service engineer network. The instrument and components must comply with ASTM D 3951 for packaging and marking, with prohibitions on peanut-type materials and asbestos-contaminated vermiculite. Packaging must ensure protection against environmental damage, shock, and contamination, including dry nitrogen backfilling for vacuum components and enhanced protection