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CUSTOM INDUCIBLE KNOCKIN MOUSE

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PCA-NIDDK-02527 Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institutes of Health intends to award a firm-fixed-price purchase order to Ingenious Targeting Laboratory Inc. for the creation of a custom inducible knockin mouse. This specific requirement involves an endogenous Gcm2 genomic modification, which distinguishes it from generic CRISPR/Cas9 mouse generation or services using heterologous promoters in a transgene. Based on market research, Ingenious Targeting Laboratory Inc. has been identified as the only responsible source capable of meeting these precise technical specifications. While this notice is not a request for competitive quotes, the government allows small businesses to submit written capability statements to demonstrate their ability to perform the requirement. Responses must be submitted to the primary point of contact by 9:00 a.m. EDT on September 1, 2026. If no other capable vendors are identified, the award is expected to be issued approximately five days after the notice date.

General Info

NIH awards Ingenious Targeting Laboratory Inc. for custom Gcm2 inducible knockin mouse creation.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

Bethesda, MD, 20892, USA

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NONE

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
Contacts1 person available
OfficeBETHESDA, MD, 20892, USA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
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Office AddressBETHESDA, MD, 20892, USA
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Full Description

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Notice of Intent: CUSTOM INDUCIBLE KNOCKIN MOUSE


                           (PCA-NIDDK-02527)


The National Institutes of Health intends to award a Firm-Fixed-Price Purchase Order to  Ingenious Targeting Laboratory Inc.


In accordance with FAR Part 6.302-1, Ingenious Targeting Laboratory Inc is the only responsible source presently identified as capable of satisfying the complete technical requirements of this Custom Inducible Knockin Mouse.


The Government determined that CRISPR/Cas9 and custom mouse-model generation services are available from multiple sources. However, the Government's requirement is for a specific endogenous Gcm2 genomic modification, rather than generic CRISPR/Cas9 mouse generation.


Alternative services offering Gcm2 expression through a heterologous promoter in a transgene do not satisfy this requirement because they do not modify the endogenous Gcm2 gene.


Based on the market research conducted to date, Ingenious Targeting Laboratory Inc. is the only responsible source identified as capable of satisfying the Government's complete technical requirement.


This notice is not a request for competitive quotes.  Ingenious Targeting Laboratory Inc. is the provider of CRISPR/Cas9 precision genomic-editing services specifically suited to the generation of the required Gcm2 knock-in mouse line this service.  However, any available small businesses (e.g., 8(a), service-disabled veteran owned small business, HUBZone small business, small disadvantaged business, veteran-owned small business, and women-owned small business) as stated herein may submit a written capability statement that clearly supports and demonstrates their ability to perform the requirement. A determination by the Government to compete this proposed award based upon responses to this notice is solely within the discretion of the Government.


It is anticipated that an award will be issued approximately five (5) days after the date of this notice unless the Government determines that another vendor has the capability to meet this requirement.


Please email responses to vensonm@mail.nih.gov no later than 09:00 a.m.  EDT on September 01, 2026.

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